A Study of Multiparametric Ultrasound Imaging (mpUS) to Check Vaginal Tissue Health in Patients With Endometrial Cancer who are Undergoing Intravaginal Brachytherapy
This clinical trial studies whether transvaginal multiparametric ultrasound imaging (mpUS) can be used to check vaginal tissue (the tissue that makes up the lining of the vagina) health before and after intravaginal brachytherapy (IVRT) in endometrial cancer patients. IVRT is routinely used to treat endometrial cancer but can cause damage to the vaginal tissue and checking the health of vaginal tissue is important in these patients. Traditional ultrasound imaging uses high-energy sound waves to look at tissues and organs inside the body. Transvaginal mpUS imaging uses a small wand-like device that is inserted into the vagina (transducer) to produce the ultrasound images. It combines different ultrasound methods to create a more detailed and accurate assessment of tissue. Standard ultrasound provides a basic image of tissue structure, but mpUS imaging can also show blood vessels, blood flow, detailed tissue structure (microstructure), and tissue elasticity (stretchiness). Researchers believe the more detailed imaging produced by transvaginal mpUS may be sensitive to vaginal tissue changes, which may be a more effective way to check vaginal tissue health before and after IVRT in endometrial cancer patients.