At-Home versus In-Clinic Helicobacter Pylori Screening among the At-Risk South Florida Community - Aim 2
This phase IV trial compares at-home versus in-clinic Helicobacter (H.) pylori screening among the at-risk South Florida community. Nearly half the people across the world are infected with a bacteria called H. pylori, which is found in their stomachs. In most people, it does not cause any health problems. But in some, it can cause stomach inflammation and, in rare cases, even stomach cancer. Not all persons with H. pylori infection are aware they have it. Healthcare providers do not routinely test for it, unless someone has symptoms of an infection. In this trial, all participants undergo testing for H. pylori called PYTEST® 14C-Urea breath test, even without symptoms. It is recommended that people with H. pylori infection undergo treatment. People with H. pylori receive a multi-medication treatment regimen called VOQUEZNA® Triple Pak® that consists of vonoprazan, amoxicillin, and clarithromycin. After testing and treatment (if someone has the bacterium), guidelines recommend retesting to ensure the bacterium is gone. This is a step that is often missed. This trial may help researchers determine whether at-home PYTEST® 14C-Urea breath testing works better than in-person clinic PYTEST® 14C-Urea breath testing in improving rates of H. pylori retesting among the at-risk South Florida community.