This proposal directly addresses the ability to safely scale-up a Screen-Triage-Treat
approach to cervical cancer screening. The investigators propose to capitalize on a pool
of screen-eligible women accessing routine care within targeted human immunodeficiency
virus (HIV) care and treatment services. The primary outcome of interest is the number of
women screened and the proportion of screen-positive women undergoing treatment.
Secondary outcomes will focus on other implementation outcomes, and if successful, will
be utilized to inform future research to take this approach to scale across Mozambique.
Study sponsor and potential other locations can be found on ClinicalTrials.gov for NCT06810739.
Locations matching your search criteria
United States
Louisiana
New Orleans
Tulane University School of MedicineStatus: Active
Contact: Troy Moon
This study will use a hybrid type III effectiveness-implementation design. In a hybrid
type III design, the primary focus is on testing of an implementation strategy, while
simultaneously continuing to observe and gather information on the effectiveness of a
clinical intervention, under real world conditions, for which effectiveness data has
already largely been determined. Best practices for deploying the Screen-Triage-Treat
approach to cervical cancer screening utilizing self-collected human papilloma virus
(HPV) deoxyribonucleic acid (DNA) testing within Mozambique´s HIV care and treatment
services will be evaluated. The study will employ a mixed-methods approach, collecting
both quantitative and qualitative data. The primary outcome of interest is the number of
women screened and the proportion of HPV screen-positive women undergoing treatment,
while secondary outcomes will focus on other implementation outcomes, and if successful,
will be utilized to inform future research to take this approach to scale across
Mozambique.
Trial PhaseNo phase specified
Trial Typescreening
Lead OrganizationTulane University School of Medicine
Principal InvestigatorTroy Moon
