Clinical Trials Using Abatacept
Clinical trials are research studies that involve people. The clinical trials on this list are studying Abatacept. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Abatacept in Treating Patients with Steroid Refractory Chronic Graft-Versus-Host Disease
This phase I / II trial studies the side effects and best dose of abatacept and to see how well it works in treating patients with chronic graft-versus-host disease that does not respond to steroid treatment. Abatacept is being studied as a treatment for graft-versus-host disease caused by a donor bone marrow or stem cell transplant.
Location: 3 locations
Abatacept, Ixazomib Citrate, and Dexamethasone in Treating Patients with Multiple Myeloma Resistant to Chemotherapy
This phase II trial studies how well abatacept, ixazomib citrate, and dexamethasone work in treating patients with multiple myeloma that is resistant to chemotherapy. Abatacept may block certain proteins that are present on multiple myeloma cells that have been shown to protect against chemotherapy. Drugs used in chemotherapy, such as ixazomib citrate and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving abatacept, ixazomib citrate, and dexamethasone may work better at treating patients with multiple myeloma resistant to chemotherapy.
Location: Roswell Park Cancer Institute, Buffalo, New York