Clinical Trials Using Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes
Clinical trials are research studies that involve people. The clinical trials on this list are studying Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Donor CMV Specific CTLs in Treating CMV Reactivation or Infection in Patients who have Undergone Stem Cell Transplant or Solid Organ Transplant
This phase I trial studies the side effects and how well allogeneic cytomegalovirus-specific cytotoxic T lymphocytes (donor cytomegalovirus [CMV] specific cytotoxic T-lymphocytes [CTLs]) work in treating CMV reactivation or infection in patients who have undergone stem cell transplant or solid organ transplant. White blood cells from donors may be able to kill viral cells in patients with cytomegalovirus that has come back after a stem cell or solid organ transplant.
Location: 2 locations
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)
CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT) or with primary immunodeficiencies (PID).
Location: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Donor Cytomegalovirus-Specific Cytotoxic T-Lymphocytes in Treating Patients with a Persistent Cytomegalovirus Infection
This phase II trial studies how well donor cytomegalovirus-specific cytotoxic T-lymphocytes work in treating patients with a cytomegalovirus infection that has come back or has not gotten better despite standard therapy. White blood cells from donors who have been exposed to cytomegalovirus may be effective in treating patients with a cytomegalovirus infection.
Location: M D Anderson Cancer Center, Houston, Texas