Clinical Trials Using Combretastatin A1 Diphosphate

Clinical trials are research studies that involve people. The clinical trials on this list are studying Combretastatin A1 Diphosphate. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w / Subsequent Ph 2 Cohorts for AML and MDS

    Phase 1 will investigate maximum tolerated dose of OXi4503 as a single agent and in combination with intermediate-dose cytarabine in subjects with relapsed / refractory AML or MDS. Phase 2 will investigate overall response rate of OXi4503 in combination with intermediate-dose cytarabine in 1) subjects with MDS after failure of 1 prior hypomethylating agent (Arm A) and 2) subjects with relapsed and refractory AML after treatment failure of up to 1 prior chemotherapy regimen (Arm B).
    Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California