Clinical Trials Using Floxuridine

Clinical trials are research studies that involve people. The clinical trials on this list are studying Floxuridine. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • Medtronic Pump and Codman Catheter in Delivering Chemotherapy Directly to the Liver in Patients with Metastatic Colorectal Cancer or Cholangiocarcinoma

    This phase II trial studies the side effects of a Medtronic pump and Codman catheter when used to deliver chemotherapy directly to the liver in patients with cholangiocarcinoma or colorectal cancer that has spread to other places in the body (metastatic). The Medtronic pump and Codman catheter are devices that are surgically placed in the liver and used to deliver treatment directly to tumor cells which may help to shrink the tumor. Drugs used in chemotherapy, such as floxuridine and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Using the Medtronic pump and Codman catheter to deliver chemotherapy may work better in treating patients with colorectal cancer or cholangiocarcinoma.
    Location: 7 locations

  • Mitomycin C or Floxuridine and Leucovorin Calcium during or after Surgery in Treating Patients with Appendiceal, Colon, or Rectal Cancer

    This randomized phase II trial studies how well mitomycin C or floxuridine and leucovorin calcium during or after surgery works in treating patients with appendiceal, colon, or rectal cancer. Drugs used in chemotherapy, such as mitomycin C, floxuridine, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether heating a chemotherapy solution and infusing it directly into the abdomen during surgery kills more tumor cells than infusing a chemotherapy solution directly into the abdomen after surgery.
    Location: 10 locations