Clinical Trials Using Fluorine F 18 Sodium Fluoride

Clinical trials are research studies that involve people. The clinical trials on this list are studying Fluorine F 18 Sodium Fluoride. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer

    Background: Prostate cancer is the second leading cause of cancer deaths in American men. Few options exist to create images of this type of cancer. Researchers think an experimental radiotracer called 18F-DCFPyL could find sites of cancer in the body. Objective: To see if 18F-DCFPyL can identify sites of prostate cancer in people with the disease. Eligibility: People ages 18 and older who have metastatic prostate cancer Design: Participants will be screened with: - Blood tests - Physical exam - Medical history Participants will be assigned to 1 of 2 groups based on their PSA. Participants will have 18F-DCFPyL injected into a vein. About 2 hours later they will have a whole-body Positron Emission Tomography / Computed Tomography (PET / CT). For the scan, they will lie on their back on the scanner table while it takes pictures of the body. This lasts about 50 minutes. On another day, participants will have 18F -NaF injected into a vein. About 1 hour later, they will have a whole-body PET / CT. Participants will be contacted 1 3 days later for follow-up. They may undergo PET / Magnetic Resonance Imaging (MRI) either after having a 18F-DCFPyL PET / CT, or in place of PET / CT imaging. A tube may be placed in the rectum. More coils may be wrapped around the outside of the pelvis. If the 18F-DCFPyL PET / CT is positive participants will be encouraged to undergo a biopsy of one of the tumors. The biopsy will be taken through a needle put through the skin into the tumor. Participants will be followed for 1 year. During this time researchers will collect information about their prostate cancer, such as PSA levels and biopsy results. About 4-6 months after scanning is completed, participants may have a tumor biopsy. The biopsy will be taken through a needle put through the skin into the tumor. ...
    Location: National Institutes of Health Clinical Center, Bethesda, Maryland

  • F18PET / CT Versus TC-MDP Scanning to Detect Bone Mets

    The primary objective is to compare the diagnostic performance of 18F- Fluoride PET / CT scanning to that of conventional bone scanning for detecting cancer that has spread to the bone (bone metastasis). The intent of the study is to determine whether 18F-Fluoride PET / CT will lead to improved treatment and patient outcomes.
    Location: See Clinical

  • Fluorine F 18 Sodium Fluoride and Fludeoxyglucose F 18 Combined Positron Emission Tomography / Computed Tomography Scan in Diagnosing Patients with Malignant Neoplasms

    This pilot research trial studies fluorine F 18 sodium fluoride (F-18 NaF) and fludeoxyglucose F 18 (F-18 FDG) combined positron emission tomography (PET) / computed tomography (CT) scan in diagnosing patients with malignant neoplasms. Diagnostic procedures, such as combined F-18 NaF / F-18 FDG PET / CT scan, may help find and diagnose cancer. It is not yet known whether F-18 NaF / F-18 FDG combined PET / CT scan is more effective than F-18 NaF or F-18 FDG PET / CT scans performed separately in diagnosing cancer.
    Location: Stanford Cancer Institute Palo Alto, Palo Alto, California