Clinical Trials Using Flutamide
Clinical trials are research studies that involve people. The clinical trials on this list are studying Flutamide. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Antiandrogen Therapy and Radiation Therapy with or without Docetaxel in Treating Patients with Prostate Cancer That Has Been Removed by Surgery
This randomized phase II / III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy alone in treating patients with prostate cancer that has been removed by surgery. Androgen can cause the growth of prostate cells. Antihormone therapy may lessen the amount of androgen made by the body. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving antiandrogen therapy and radiation therapy with or without docetaxel after surgery may kill any remaining tumor cells.
Location: 237 locations
Standard Systemic Therapy with or without Definitive Treatment in Treating Participants with Metastatic Prostate Cancer
This phase III trial studies whether the addition of definitive treatment (radiation or surgical removal) of the primary tumor to standard systemic therapy for patients with prostate cancer, may help prevent the cancer from the spreading to other parts of their body. Removing the prostate by either surgery or radiation therapy in addition to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.
Location: 174 locations
Flutamide in Treating Patients with Prostate Cancer on Androgen Suppression Undergoing Brachytherapy
This phase II trial studies how well flutamide works in treating patients with prostate cancer on androgen suppression undergoing brachytherapy. Flutamide blocks the effects of testosterone and slows the growth and spread of tumor cells. Giving flutamide before brachytherapy may work better in patients with prostate cancer on androgen suppression.
Location: Johns Hopkins University / Sidney Kimmel Cancer Center, Baltimore, Maryland