Clinical Trials Using Glucarpidase

Clinical trials are research studies that involve people. The clinical trials on this list are studying Glucarpidase. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • Glucarpidase in Treating Patients with Central Nervous System B-Cell Non-Hodgkin Lymphoma

    This early phase I trial studies how well glucarpidase works in treating patients with central nervous system B-cell non-Hodgkin lymphoma. Glucarpidase is a type of bacterial enzyme that breaks down proteins and other substances. It may also help activate certain drugs to kill cancer. Giving glucarpidase may work better in treating patients with central nervous system B-cell non-Hodgkin lymphoma.
    Location: 8 locations

  • Glucarpidase after High-Dose Methotrexate in Patients with Osteosarcoma

    This early phase I trial studies how well glucarpidase works in reducing toxicity in patients with osteosarcoma receiving high dose methotrexate treatment. Glucarpidase may reduce the levels of methotrexate in patients’ blood and lead to shorter hospitalizations and a reduction in toxicities.
    Location: 3 locations