Clinical Trials Using Omacetaxine Mepesuccinate

Clinical trials are research studies that involve people. The clinical trials on this list are studying Omacetaxine Mepesuccinate. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Omacetaxine and Azacitidine in Treating Participants with High Grade Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

    This phase I / II trial studies the side effects and best dose of omacetaxine mepesuccinate (omacetaxine) and how well it works when given together with azacitidine in treating participants with high grade myelodysplastic syndrome or chronic myelomonocytic leukemia. Drugs used in chemotherapy, such as omacetaxine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Azacitidine may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving omacetaxine and azacitidine may work better at treating participants with myelodysplastic syndrome or chronic myelomonocytic leukemia.
    Location: University of Colorado Hospital, Aurora, Colorado