Clinical Trials Using Tamoxifen Citrate
Clinical trials are research studies that involve people. The clinical trials on this list are studying Tamoxifen Citrate. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Tamoxifen Citrate, Anastrozole, or Fulvestrant in Treating Patients with Stage I-III Invasive Lobular Breast Cancer
This phase II trial studies how well tamoxifen citrate, anastrozole, or fulvestrant work in treating patients with stage I-III invasive lobular breast cancer. Tamoxifen citrate and anastrozole may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as fulvestrant, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving tamoxifen citrate, anastrozole, or fulvestrant will work better in treating patients with invasive lobular breast cancer.
Location: 12 locations
Tamoxifen for the Treatment of Hormone Receptor Positive, Well Differentiated Neuroendocrine Tumors, the HORMONET Study
This phase II trial studies how well tamoxifen works in treating patients with hormone receptor positive, well differentiated neuroendocrine tumors. Hormones, like estrogen and progesterone, can encourage tumors to grow. Tamoxifen is a drug that may block / suppress the production of estrogen and progesterone, and therefore lower the amount of hormone in the body.
Location: Moffitt Cancer Center, Tampa, Florida
Fulvestrant and Tamoxifen Citrate in Treating Patients with Estrogen Receptor Positive Metastatic Breast Cancer
This randomized phase II trial studies how well fulvestrant and tamoxifen citrate work in treating patients with estrogen receptor positive breast cancer that has spread to other parts of the body. Estrogen can cause the growth of breast tumor cells. Hormone therapy using fulvestrant and tamoxifen citrate may fight estrogen receptor positive metastatic breast cancer by blocking the use of estrogen by the tumor cells.
Location: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Tamoxifen Citrate or Aromatase Inhibitor in Treating Elderly Patients with Estrogen Receptor Positive Breast Cancer That Can Be Removed by Surgery
This phase II trial studies how well tamoxifen citrate or aromatase inhibitor works in treating elderly patients with estrogen receptor positive breast cancer that can be removed by surgery. Hormone therapy using tamoxifen citrate or aromatase inhibitor may fight estrogen receptor positive breast cancer by lowering the amount of estrogen the body makes and by blocking the use of estrogen by the tumor cells.
Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri
Ovarian Simulation and Tamoxifen or Letrozole in Fertility Preservation in Patients with Breast Cancer, TALES Study
This randomized phase IV trial studies how well ovarian stimulation and tamoxifen or letrozole work in fertility preservation in patients with breast cancer. Ovarian stimulation uses medicines such as gonadotrophins to stimulate the ovaries to mature more eggs. Tamoxifen may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and blocks the effects of estrogen. Letrozole may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and lower the body's estrogen levels. It is now yet know whether giving ovarian stimulation with tamoxifen or letrozole may work better in amount of mature eggs being retrieved.
Location: 2 locations