Clinical Trials Using Topical Fluorouracil

Clinical trials are research studies that involve people. The clinical trials on this list are studying Topical Fluorouracil. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Topical Fluorouracil and Imiquimod in Treating Patients with High-Grade Cervical Intraepithelial Neoplasia

    This early phase I clinical trial studies the side effects of topical fluorouracil and imiquimod ointment in treating patients with high-grade cervical intraepithelial neoplasia. Topical fluorouracil may kill precancerous cells. Imiquimod ointment may stimulate the immune system. Applying topical fluorouracil and imiquimod ointment may cause fewer side effects and may be a better way to treat patients with precancerous cervical lesions.
    Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina