2015 - CCG Updates & Insights
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The Cancer Genome Atlas: More Than a Large Collection of DataThough TCGA will wrap up in 2016 with a concluding symposium, cancer genomics projects built upon the success of TCGA will continue to play a major part in the NCI’s mission to better understand and treat cancer in the years to come.
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Cancer Informatics: Expanding Access to Cancer Genomics DataDrs. Staudt and Kibbe discuss the NCI’s major initiatives to improve both the accessibility and usability of cancer genomics data. Top among the NCI’s priorities are the Genomic Data Commons, a service that will bring together and harmonize cancer genomic data sets from NCI programs and non-NCI data submitters, and the Cancer Genomics Cloud Pilots.
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Researcher Interview: Matthew MeyersonIn this interview, Matthew Meyerson, M.D., Ph.D., Professor of Pathology at Dana-Farber Cancer Institute and Harvard Medical School, talks about the clinical impact of his research on lung cancer and discusses developing technologies and ongoing challenges in the field of cancer genomics.
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Funding Opportunity: Genomic Data Analysis Network CentersThe National Cancer Institute (NCI) has published three companion Funding Opportunity Announcements (FOAs) for Genomic Data Analysis Network Centers to support programs of the Center for Cancer Genomics (CCG). The FOAs are managed by CCG and solicit applications for a Processing Genomic Data Center, a Visualization Genomic Data Center, and a Specialized Genomic Data Center.
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Study Identifies Biomarker that Detects Early Pancreatic CancerResearchers from the University of Texas MD Anderson Cancer Center have identified a protein marker that is found at much higher levels in exosomes that derive from cancer cells compared to healthy cells, a discovery that may improve the detection and treatment of pancreatic cancer.
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Researcher Interview: Tom HudsonTom Hudson, M.D., President and Scientific Director of the Ontario Institute for Cancer Research, describes the International Cancer Genome Consortium (ICGC), which brings together cancer genomic data and research from across the world.
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Divide and Conquer: The Molecular Diagnosis of CancerCCG promotes the transformation of cancer diagnosis and treatment through genomics. Using a “team science” approach, CCG supports research in structural, functional, and computational genomics that provide data and resources to the cancer research community.
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Researchers use Modified CRISPR Systems to Modulate Gene Expression on a Genomic ScaleCancer Target Discovery and Development Network (CTD2) researchers at the University of California, San Francisco, developed a CRISPR system that can regulate both gene repression and activation with fewer off-target effects.
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American Society of Clinical Oncology (ASCO) Recognizes TCGA’s Importance in the Past Decade and in Tumor BiologyThe American Society of Clinical Oncology (ASCO) highlighted TCGA’s role in advancing knowledge about cancer genes, pathways, and subtypes, in its 2015 Annual Report on Progress Against Cancer.
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Researcher Interview: Elaine MardisElaine Mardis Ph.D., Professor of Medicine at Washington University School of Medicine, discusses her translational research applying genomics techniques to clinical trials, and forecasts the future of team science and cancer genomics.