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Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Treatment Clinical Trials for Anal Cancer

Review the anal cancer treatment clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 1-18 of 18

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Status: Active
Location: 16 locations
Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer
Status: Active
Location: 13 locations
Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Patients with Early-Stage Anal Cancer
Status: Active
Location: 4 locations
SMP-3124LP in Adults With Advanced Solid Tumors
Status: Active
Location: 3 locations
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
Status: Active
Location: 3 locations
Curcumin for the Treatment of Precancerous Anal Lesions in Patients with HIV
Status: Active
Location: 2 locations
Comparing Length of Treatment with Immunotherapy in Patients with Advanced Solid Tumors
Status: Active
Location: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
REDEL Trial: Reduced Elective Nodal Dose for Anal Cancer Toxicity Mitigation
Status: Active
Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Lenvatinib and Pembrolizumab for the Treatment of Unresectable, Locally Advanced, or Metastatic Anorectal Squamous Cell Cancer
Status: Active
Location: University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Combined Immunotherapy with Ipilimumab and Nivolumab or Nivolumab and Relatlimab and Radiation Therapy before Surgery for the Treatment of Sinonasal and Anorectal Melanoma
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers
Status: Active
Location: University of California San Francisco, San Francisco, California
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
Status: Active
Location: Hackensack University Medical Center, Hackensack, New Jersey
E7 TCR-T Cell Induction Therapy for the Treatment of Locoregionally Advanced HPV-Associated Cancers
Status: Active
Location: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey
Papaverine Hydrochloride and Stereotactic Body Radiation Therapy in Treating Patients with Non-small Cell Lung Cancer or Lung Metastases
Status: Active
Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Physical Therapy and Coping Skills Training for Improving Women's Sexual Function after Pelvic Radiation
Status: Active
Location: Duke University Medical Center, Durham, North Carolina
Adaptive Radiotherapy for the Treatment of Patients with Locally Advanced Anal Cancer
Status: Active
Location: NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Pomalidomide and Nivolumab for the Treatment of Virus-Associated Malignancies with or without HIV
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland