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Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Clinical Trials Using Irinotecan Hydrochloride

Review the clinical trials studying irinotecan hydrochloride on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 1-16 of 16

Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers
Status: Active
Location: 448 locations
Testing the Use of the Usual Chemotherapy before and after Surgery for Removable Pancreatic Cancer
Status: Active
Location: 338 locations
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Status: Active
Location: 171 locations
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Status: Active
Location: 34 locations
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Status: Active
Location: 8 locations
Chemoradiation with Combination Chemotherapy for the Treatment of Rectal Cancer
Status: Active
Location: 5 locations
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Status: Active
Location: 4 locations
Early Identification and Treatment of Occult Metastatic Disease in Stage III Colon Cancer
Status: Active
Location: 3 locations
Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer
Status: Active
Location: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of gFOLFIRINOX in Treating Patients with Locally Advanced Gastroesophageal or Stomach Cancer
Status: Active
Location: 2 locations
Erlotinib, Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Basal-Like Pancreatic Cancer, PANGEA Trial
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
A Study of Repotrectinib in Combination with Chemotherapy in Children and Young Adults with Solid Tumor Cancer
Status: Active
Location: Memorial Sloan Kettering Cancer Center, New York, New York
TAS-102 and Irinotecan after Surgery for the Treatment of ctDNA Positive, Stage II-III Colorectal Cancer
Status: Active
Location: UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
Status: Active
Location: See ClinicalTrials.gov
Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed with Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
Status: Active
Location: See ClinicalTrials.gov
Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients with Metastatic Colorectal Cancer
Status: Temporarily Closed to Accrual
Location: M D Anderson Cancer Center, Houston, Texas