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Thyroid Cancer Clinical Trials

Review the thyroid cancer clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 1-25 of 28

Study of Targeted Therapy vs. Chemotherapy in Patients with Thyroid Cancer
Status: Active
Location: 281 locations
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Status: Active
Location: 16 locations
A Study of EP0031 in Patients With Advanced RET-altered Malignancies
Status: Active
Location: 12 locations
SLV-154 Treatment of Metastatic Solid Tumors
Status: Active
Location: 4 locations
Cyclophosphamide and Sirolimus and in Treating Patients with Metastatic, Radioiodine-Refractory Thyroid Cancer
Status: Active
Location: University of Michigan Rogel Cancer Center, Ann Arbor, Michigan
Treatment of Pembrolizumab in Metastatic or Unresectable Anaplastic/Undifferentiated Thyroid Cancer
Status: Active
Location: Stanford Cancer Institute Palo Alto, Palo Alto, California
Vudalimab for the Treatment of Locally Advanced or Metastatic Anaplastic Thyroid Cancer or Hurthle Cell Thyroid Cancer
Status: Active
Location: Northwestern University, Chicago, Illinois
Lower Dose Versus Standard Dose Lenvatinib for the Treatment of Symptomatic or Progressive Radioactive Iodine Resistant Differentiated Thyroid Cancer
Status: Active
Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri
Selpercatinib Prior to Radioiodine Therapy for the Treatment of Children, Adolescents, and Young Adults with Metastatic Differentiated Thyroid Cancers that Harbor a RET Fusion, RAISE Trial
Status: Active
Location: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
XL092 for the Treatment of Locally Advanced or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer
Status: Active
Location: Northwestern University, Chicago, Illinois
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Radiation Therapy and Radioactive Iodine for the Treatment of Recurrent Papillary or Follicular Thyroid Cancer
Status: Active
Location: Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
XL092 and Cemiplimab for the Treatment of BRAF V600E-Wild Type Anaplastic Thyroid Cancer, NEO-COMBAT XL Trial
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
The Efficacy of CASAD in Patients With Diarrhea Related to Medullary Thyroid Cancer
Status: Active
Location: See ClinicalTrials.gov
Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer
Status: Temporarily Closed to Accrual
Location: 4 locations
Atezolizumab with Chemotherapy in Treating Patients with Anaplastic or Poorly Differentiated Thyroid Cancer
Status: Temporarily Closed to Accrual
Location: M D Anderson Cancer Center, Houston, Texas
JSI-1187-01 Monotherapy and in Combination With Dabrafenib for Advanced Solid Tumors With MAPK Pathway Mutations
Status: Temporarily Closed to Accrual
Location: See ClinicalTrials.gov
Patient Decision Aid in Supporting Decision-Making about When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients with Medullary Thyroid Cancer and Their Caregivers
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
An Investigational Scan (I-124 PET/CT) for Diagnosing Metastasis in Patients with Thyroid Cancer
Status: Active
Location: University of California San Francisco, San Francisco, California
New PET Scan (68Ga-FAPI-46) for People with Cancers
Status: Active
Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
Evaluating the Role of Environmental Factors in Thyroid Cancer
Status: Active
Location: 3 locations
Thyroid and Neck Ultrasound in Identifying Genomic Predictors of Tumor Progression in Patients with Thyroid Cancer
Status: Active
Location: 2 locations
Cultural Adaptation of an Educational Tool in Medullary Thyroid Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Natural History Study of Children and Adults With Medullary Thyroid Cancer
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Clinical and Genetic Studies in Familial Non-medullary Thyroid Cancer
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland