Clinical Trials Using Bupivacaine Hydrochloride
Clinical trials are research studies that involve people. The clinical trials on this list are studying Bupivacaine Hydrochloride. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Ultrasound-Guided Serratus Anterior Plane Block for Additional Pain Relief after Lung Surgery
This trial studies how well serratus anterior plane block works in relieving pain in patients who are undergoing lung surgery. Serratus anterior plane block involves injection of a local anesthetic called bupivacaine under the serratus anterior muscle (located on the first 8 ribs on the side of the chest). Two other medications, clonidine and dexamethasone, are added to the local anesthetic to make the numbing effect of bupivacaine last longer. Giving serratus anterior plane block during lung surgery may help to minimize the use of opioids after surgery.
Location: 6 locations
Epidural-General Anesthesia or General Anesthesia in Reducing Complications and Improving Survival in Patients Undergoing Pancreaticoduodenectomy
This phase III trial studies epidural-general anesthesia to see how well it works compared to general anesthesia in reducing complications in patients undergoing pancreaticoduodenectomy. An epidural that consists of bupivacaine hydrochloride and fentanyl during and after surgery may work better in reducing complications and improving survival compared to after surgery only.
Location: 3 locations
Four Quadrants Transverse Abdominus Plane Block with Bupivacaine Hydrochloride and Liposomal Bupivacaine in Treating Participants Undergoing Cytoreductive Surgery
This phase III trial studies how well four quadrants transverse abdominus plane block with bupivacaine hydrochloride and liposomal bupivacaine work in treating participants undergoing specialized abdominal surgery for cancer. Four quadrants transverse abdominus plane block is a procedure that delivers anesthesia such as bupivacaine hydrochloride and liposomal bupivacaine to help relieve pain after surgery. Four quadrants transverse abdominus plane block may work better in relieving pain after cytoreductive surgery.
Location: M D Anderson Cancer Center, Houston, Texas
Stellate Ganglion Blockade with Bupivacaine Hydrochloride in Reducing Hot Flashes in Hispanic Patients with Breast Cancer
This phase II trial studies how well a stellate ganglion blockade with bupivacaine hydrochloride works in reducing hot flashes in Hispanic patients with breast cancer. A stellate ganglion blockade using bupivacaine hydrochloride (a local anesthetic used to block signals at nerve endings) may help to reduce the number and severity of hot flashes in Hispanic patients with breast cancer.
Location: Northwestern University, Chicago, Illinois
Bupivacaine Hydrochloride in Controlling Pain in Patients with Breast Cancer after Surgery
This randomized phase III trial studies how well bupivacaine hydrochloride works in controlling pain in patients with breast cancer after surgery. Bupivacaine hydrochloride may help relieve moderate or severe pain caused by surgery.
Location: 7 locations
Image Guided Cryosurgery in Managing Post Mastectomy Pain Syndrome in Patients That Have Undergone Mastectomy, Partial Mastectomy, Lumpectomy, or Breast Reconstruction
This randomized pilot phase II trial studies how well image guided cryosurgery works in managing post mastectomy pain syndrome in patients that have undergone mastectomy, partial mastectomy, lumpectomy, or breast reconstruction. Image guided cryosurgery involves using a computed tomography (CT) scan to help guide a needle inserted through the skin into the targeted nerve, and uses a freezing effect that may work better in reducing the pain felt from the mastectomy, partial mastectomy, lumpectomy, or breast reconstruction.
Location: 4 locations
Abdominal Nerve Catheter Blocks Using the Nimbus Ambulatory Infusion System in Reducing Pain in Patients with Breast Cancer Undergoing Breast Reconstruction Surgery
This randomized phase III trial compares blocking the abdominal nerves using an infusion of local anesthetic (using the Nimbus Ambulatory Infusion System) or a placebo (inactive treatment) before surgery in reducing pain in patients with breast cancer undergoing breast reconstruction surgery. The transversus abdominis (abdominal nerves) plane block is a procedure that targets the nerves near the surgical area and when given before surgery may improve patient comfort and reduce pain medication use after surgery.
Location: Stanford Cancer Institute Palo Alto, Palo Alto, California
Scalp Block in Controlling Vital Signs and Pain in Patients with Brain Tumors Undergoing Surgery
This randomized phase I trial studies how well scalp block works in controlling vital signs and pain in patients with brain tumors undergoing surgery. Administering a local anesthetic, a mixture of two medications called lidocaine and bupivacaine, to numb the scalp may provide better control of heart rate, blood pressure, and pain relief during and after the surgery.
Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri