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azaribine

The triacetate salt of azauridine, a synthetic triazine nucleoside derivative possessing antineoplastic and anti-psoriatic activity. After metabolism to 6-azauridine-5-prime monophosphate, 6-Azauridine inhibits de novo pyrimidine biosynthesis and its 5-prime triphosphate metabolite gets incorporated into RNA, thereby preventing RNA synthesis.
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Synonym:6-azauridine triacetate
azauridine triacetate
triazure
Chemical structure:1,2,4-triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl-
2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-as-triazine-3,5(2H,4H)-dione
2',3',4'-azauridine triacetate
triacetyl 6-azuridine
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