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Drug:  omacetaxine mepesuccinate
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A Study to Evaluate the Pharmacokinetics, Safety,and Efficacy of Omacetaxine Given Subcutaneously as a Fixed Dose in Patients With Chronic Phase (CP) or Accelerated Phase (AP) Chronic Myeloid Leukemia (CML) (Referred to as the SYNSINCT Study)
Status: Active
Phase: Phase II, Phase I
Type: Biomarker/Laboratory analysis, Treatment
Age: 18 and over
Trial IDs: C41443/2057, NCI-2014-01456, 2013-005320-42, NCT02078960
Omacetaxine Mepesuccinate and Decitabine in Treating Older Patients with Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Status: Active
Phase: Phase II, Phase I
Type: Treatment
Age: 70 and over
Trial IDs: 2013-0812, NCI-2014-02157, NCT02141477
Omacetaxine Mepesuccinate in Treating Patients with Intermediate-1 Risk or Higher Risk Myelodysplastic Syndrome That Has Not Responded to Chemotherapy Agents
Status: Active
Phase: Phase II
Type: Treatment
Age: 18 and over
Trial IDs: 2013-0870, NCI-2014-01483, NCT02159872
Omacetaxine Mepesuccinate after Cytarabine and Daunorubicin Hydrochloride, Idarubicin, or Mitoxantrone Hydrochloride in Treating Older Patients with Acute Myeloid Leukemia in First Remission
Status: Active
Phase: No phase specified
Type: Treatment
Age: 60 and over
Trial IDs: Winship2176-11, NCI-2013-01131, IRB00057844, NCT01873495
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