Cancer Care Delivery in Adolescent and Young Adult Patients with Acute Lymphoblastic Leukemia
Inclusion Criteria
- Newly diagnosed with either Ph- or Ph+ ALL between January 1st, 2012 and December 31st, 2016
- Both diagnosed and initially treated at the participating National Cancer Institute Community Oncology Research Program (NCORP) institution during induction and post-induction therapy (PIT)
- Aim 3: Healthcare professional currently employed at a participating NCORP institution * Eligible healthcare providers include but are not limited to: physicians, registered nurses (RNs), nurse practitioners, physician assistants, patient advocates, social workers, pharmacists and clinical research associates (CRAs)
- Aim 3: Direct involvement in the care of AYA ALL patients
Exclusion Criteria
- Diagnosis of secondary ALL
- Diagnosis of mixed lineage acute leukemia
- Diagnosis of acute leukemia of ambiguous lineage (ALAL)
- Diagnosis of Burkitt’s leukemia
- Transfer of care to another institution during induction or post-induction therapy (PIT)
- Aim 3: Trainee
Alaska
Anchorage
Fairbanks
Arkansas
Ft. Smith
Hot Springs
Jonesboro
California
Anaheim
Antioch
Arroyo Grande
Baldwin Park
Bellflower
Burbank
Dublin
Fontana
Fremont
Fresno
Harbor City
Irvine
Los Angeles
Modesto
Oakland
Ontario
Panorama City
Rancho Cordova
Redwood City
Richmond
Riverside
Rohnert Park
Roseville
Sacramento
San Diego
San Francisco
San Jose
San Marcos
San Rafael
Santa Clara
Santa Rosa
South San Francisco
Stockton
Vacaville
Vallejo
Walnut Creek
Woodland Hills
Colorado
Aurora
Boulder
Colorado Springs
Denver
Durango
Englewood
Golden
Grand Junction
Greeley
Lafayette
Lakewood
Littleton
Lone Tree
Longmont
Loveland
Parker
Pueblo
Thornton
Wheat Ridge
Delaware
Lewes
Newark
Rehoboth Beach
Seaford
Wilmington
Florida
Fort Lauderdale
Fort Myers
Hollywood
Jacksonville
Orlando
Tampa
Georgia
Atlanta
Augusta
Hawaii
Aiea
Honolulu
Lihue
Idaho
Boise
Caldwell
Emmett
Fruitland
Meridian
Nampa
Twin Falls
Illinois
Bloomington
Canton
Carbondale
Carterville
Carthage
Centralia
Chicago
Decatur
Dixon
Effingham
Eureka
Galesburg
Kewanee
Macomb
O'Fallon
Ottawa
Pekin
Peoria
Peru
Princeton
Springfield
Swansea
Iowa
Clive
Council Bluffs
Creston
Des Moines
West Des Moines
Kentucky
Bardstown
Corbin
Lexington
London
Louisville
Shepherdsville
Louisiana
New Orleans
Massachusetts
Springfield
Michigan
Ann Arbor
Battle Creek
Brighton
Canton
Caro
Chelsea
Clarkston
Detroit
East China
Escanaba
Flint
Grand Rapids
Grosse Pointe Woods
Kalamazoo
Lansing
Livonia
Macomb Township
Marlette
Muskegon
Niles
Pontiac
Port Huron
Reed City
Rochester Hills
Saginaw
Saint Joseph
Sterling Heights
Tawas City
Traverse City
Warren
West Branch
Wyoming
Ypsilanti
Minnesota
Brainerd
Burnsville
Cambridge
Coon Rapids
Deer River
Detroit Lakes
Duluth
Edina
Fergus Falls
Fosston
Fridley
Hibbing
Maple Grove
Maplewood
Minneapolis
Monticello
New Ulm
Park Rapids
Princeton
Robbinsdale
Saint Louis Park
Saint Paul
Sandstone
Shakopee
Stillwater
Virginia
Waconia
Willmar
Woodbury
Wyoming
Mississippi
Columbus
Grenada
New Albany
Oxford
Southhaven
Missouri
Bonne Terre
Cape Girardeau
Farmington
Jefferson City
Saint Louis
Sainte Genevieve
Springfield
Sullivan
Sunset Hills
Montana
Billings
Butte
Missoula
Nebraska
Grand Island
Kearney
Lincoln
Omaha
Papillion
Nevada
Carson City
Henderson
Las Vegas
Pahrump
Reno
New Mexico
Albuquerque
New York
Bronx
Lake Success
New York
North Dakota
Fargo
Jamestown
Ohio
Cincinnati
Oregon
Baker City
Bend
Clackamas
Coos Bay
Newberg
Ontario
Portland
Pennsylvania
Allentown
Bethlehem
Bryn Mawr
Chadds Ford
Danville
East Stroudsburg
Hazleton
Lewisburg
Lewistown
Media
Paoli
Pottsville
Scranton
Selinsgrove
State College
Wilkes-Barre
Wynnewood
Puerto Rico
San Juan
South Carolina
Boiling Springs
Easley
Gaffney
Greenville
Greer
Seneca
Spartanburg
Union
South Dakota
Sioux Falls
Tennessee
Chattanooga
Collierville
Hixson
Memphis
Ooltewah
Texas
Austin
Bryan
Corpus Christi
San Antonio
Utah
American Fork
Cedar City
Logan
Murray
Ogden
Provo
Riverton
Saint George
Salt Lake City
Washington
Aberdeen
Auburn
Bellingham
Bremerton
Burien
Centralia
Edmonds
Enumclaw
Everett
Federal Way
Gig Harbor
Issaquah
Kennewick
Lacey
Lakewood
Longview
Port Townsend
Poulsbo
Puyallup
Seattle
Shelton
Spokane
Spokane Valley
Tacoma
Vancouver
Walla Walla
Yelm
Wisconsin
Ashland
Green Bay
La Crosse
Manitowoc
Marinette
New Richmond
Oconto Falls
Sheboygan
Sturgeon Bay
Wyoming
Cheyenne
PRIMARY OBJECTIVES:
I. To evaluate the proportion of adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL) patients with a documented treatment plan consistent with NCCN guidelines for AYAs with ALL.
II. To evaluate the proportion of AYA ALL patients whose delivered treatment during induction and post-induction therapy (PIT) is consistent with NCCN guidelines for AYAs with ALL.
III. To determine the impact of treating physician specialty and facility type on likelihood of AYA ALL patients having a documented treatment plan concordant with NCCN guidelines when stratified by age group (15-17year[y], 18-21y, and 22-39y).
IV. To determine the impact of treating physician specialty and facility type on the likelihood of AYA ALL patients receiving induction and post-induction therapy (PIT) concordant with NCCN guidelines when stratified by age group (15-17y, 18-21y, and 22-39y).
V. To identify for AYAs with ALL, targetable structure- and process-level barriers and facilitators which will increase the proportion of patients having a documented treatment plan and receiving treatment according to NCCN guidelines.
EXPLORATORY OBJECTIVE:
I. To explore potential correlations with clinical and social demographic variables to the presence of a documented treatment plan and delivered treatment consistent with NCCN guidelines in AYAs with ALL.
OUTLINE:
CHART REVIEW: Patient medical record data is abstracted and treatment plans are reviewed for consistency to NCCN guidelines. For each patient, induction and post-induction care is recorded as either concordant with NCCN guidelines or non-concordant with NCCN guidelines.
SITE QUESTIONNAIRE: Participating sites complete a questionnaire which is designed to capture facility-oriented data.
FOCUS GROUPS: Healthcare providers participate in focus groups over 2-3 hours to discuss facilitators and barriers to AYA ALL guideline concordance. Participants provide responses which will be recorded on a flip-chart or white board, followed by discussion of the ideas for clarification.
Trial Phase Phase NA
Trial Type Health services research
Lead Organization
Children's Oncology Group
Principal Investigator
Julie Anna Wolfson
- Primary ID ACCL16N1CD
- Secondary IDs NCI-2017-01053, COG-ACCL16N1CD
- Clinicaltrials.gov ID NCT03204916