Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed By the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed By Surgery

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Status: Active

Description

This randomized phase II-R/III trial studies gemcitabine hydrochloride with or without erlotinib hydrochloride followed by the same chemotherapy regimen with or without radiation therapy and capecitabine or fluorouracil in treating patients with pancreatic cancer that was removed by surgery. Drugs used in chemotherapy, such as gemcitabine hydrochloride, capecitabine, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells. Giving chemotherapy together with or without erlotinib hydrochloride and/or radiation therapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether chemotherapy is more effective when given with or without erlotinib hydrochloride and/or radiation therapy in treating pancreatic cancer.

Eligibility Criteria

Inclusion Criteria

  • Histologic proof of primary head of pancreas invasive adenocarcinoma managed with a potentially curative resection (i.e., removal of all gross tumor) involving a classic pancreaticoduodenectomy (Whipple) or a pylorus preserving pancreaticoduodenectomy; patients with invasive adenocarcinoma that also contains a component of intraductal papillary mucinous neoplasm (IPMN) are eligible * The operating surgeon must document in the operative note that a complete gross excision of the primary tumor was achieved; the pathology report must include documentation of the margin status and the size of the tumor; the pathology report must also include the status of the three major margins—bile duct, pancreatic parenchyma, and retroperitoneal (uncinate)
  • For patients who have not started their chemotherapy prior to registration, the interval between definitive tumor-related surgery and 1st step registration must be between 21-70 days; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, the interval between definitive tumor-related surgery and day one of adjuvant chemotherapy must be between 21-77 days
  • Patients will be staged according to the 6th edition American Joint Committee on Cancer (AJCC) staging system with pathologic stage T1-3, N0-1, M-0 being eligible
  • Zubrod performance status 0 or 1
  • Complete history and physical examination including weight and Zubrod status within 31 days of study entry (or within 31 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Before starting therapy the patient should be able to maintain adequate oral nutrition of >= 1500 calories estimated caloric intake per day and be free of significant nausea and vomiting
  • Complete blood count (CBC)/differential obtained within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Absolute neutrophil count (ANC) >= 1,500/mm^3
  • Platelets >= 100,000/mm^3
  • Hemoglobin (Hgb) >= 8.0 g/dL (transfusion or other intervention to achieve Hgb >= 8.0 g/dl is acceptable)
  • Post resection serum cancer antigen (CA)19-9 =< 180 units/mL AND prior to any systemic treatment
  • Serum total bilirubin =< twice the institutional upper limit of normal (ULN) within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Creatinine levels =< twice the institutional upper limit of normal within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Serum glutamic oxaloacetic transaminase (SGOT) must be =< 2.5 x institutional ULN within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Negative serum pregnancy test for women of childbearing potential within 14 days of study registration
  • Abdominal/pelvic computed tomography (CT) scan with contrast is preferred; abdominal CT alone is acceptable only if insurance restrictions are experienced; chest CT/x-ray (CT of chest preferred) within 31 days of registration on study (or within 31 days prior to day 1 of chemo post-surgery for those patients having started chemotherapy prior to first step registration); patients allergic to intravenous (IV) contrast can have magnetic resonance imaging (MRI) of the abdomen/pelvis instead
  • Signed study-specific informed consent
  • Consultation, agreement, and documentation in the patient’s chart by a radiation oncologist that patient is suitable to receive radiotherapy per this protocol
  • Women of childbearing potential and male participants must practice adequate contraception
  • Patients with active human immunodeficiency virus (HIV) infection are eligible if their cluster of differentiation (CD)4 count is > 499/cu mm and their viral load is < 50 copies/ml; use of highly active antiretroviral treatment (HAART) is allowed

Exclusion Criteria

  • Patients with non-adenocarcinomas, adenosquamous carcinomas, islet cell (neuroendocrine) tumors, cystadenomas, cystadenocarcinomas, carcinoid tumors, duodenal carcinomas, distal bile duct, and ampullary carcinomas; patients with tumors that are largely IPMN with a minimal or minor component of invasive carcinoma are not eligible; patients with acinar carcinomas are not eligible; patients with IPMN’s that contain some secondary (minor) foci of adenocarcinoma are also not eligible
  • Patients managed with a total pancreatectomy, a distal pancreatectomy, or central pancreatectomy
  • Patients entering on the study after pancreaticoduodenectomy, who have not already started chemotherapy must not have had prior systemic chemotherapy for pancreas cancer; note that prior chemotherapy for a different cancer is allowable; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, patients must not have received adjuvant chemotherapy with agents other than gemcitabine, nab-paclitaxel, oxaliplatin, fluoropyrimidine, or irinotecan for the current pancreatic cancer; prior chemotherapy for a different cancer is allowable
  • Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields
  • Previous history of invasive malignancy (except non-melanoma skin cancer) unless the patient has been disease free for at least 2 years prior to study entry (or first day of chemotherapy for patients having started chemotherapy prior to first step registration); patients with a previous history of carcinoma in situ are eligible
  • Severe, active co-morbidity, defined as follows per time points indicated below (or per time points indicated below prior to the first day of chemotherapy for patients having started chemotherapy prior to first step registration): * Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months * Transmural myocardial infarction within the 3 months of study registration * Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration * Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
  • Pregnant or lactating women
  • Women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception
  • If surgical margin status cannot be determined after consultation with the operating surgeon and the institutional pathologist, the patient will be ineligible

Locations & Contacts

Alabama

Providence Hospital
Status: Temporarily closed to accrual
Mobile, Alabama
Contact: Thaddeus A. Beeker
Phone: 251-445-9870 Email: pfrancisco@usouthal.edu

Alaska

Alaska Breast Care and Surgery LLC
Status: Temporarily closed to accrual
Anchorage, Alaska
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Alaska Women's Cancer Care
Status: Temporarily closed to accrual
Anchorage, Alaska
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Katmai Oncology Group
Status: Temporarily closed to accrual
Anchorage, Alaska
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Alaska Medical Center
Status: Temporarily closed to accrual
Anchorage, Alaska
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org

Arizona

Mayo Clinic in Arizona
Status: Temporarily closed to accrual
Scottsdale, Arizona
Contact: Michael G. Haddock
Phone: 855-776-0015

California

Alta Bates Summit Medical Center - Summit Campus
Status: Active
Oakland, California
Contact: James Henry Feusner
Phone: 510-450-7600
Bay Area Tumor Institute
Status: Active
Oakland, California
Contact: James Henry Feusner
Phone: 510-450-7600
California Cancer Center - North Fresno
Status: Active
Fresno, California
Contact: Uma G. Swamy
Phone: 559-447-4050
California Pacific Medical Center-Pacific Campus
Status: Active
San Francisco, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Cedars Sinai Medical Center
Status: Temporarily closed to accrual
Los Angeles, California
Contact: Nicholas Naumann Nissen
Phone: 310-423-8965
Doctors Medical Center- JC Robinson Regional Cancer Center
Status: Temporarily closed to accrual
San Pablo, California
Contact: Jon M. Greif
Phone: 510-465-2242 Email: lradke@bati.org
East Bay Radiation Oncology Center
Status: Temporarily closed to accrual
Castro Valley, California
Contact: Jon M. Greif
Phone: 510-465-2242 Email: lradke@bati.org
Epic Care-Dublin
Status: Temporarily closed to accrual
Dublin, California
Contact: Jon M. Greif
Phone: 510-465-2242 Email: lradke@bati.org
Fresno Cancer Center
Status: Active
Fresno, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Highland General Hospital
Status: Temporarily closed to accrual
Oakland, California
Contact: Jon M. Greif
Phone: 510-465-2242 Email: lradke@bati.org
Kaiser Permanente - Sacramento
Status: Temporarily closed to accrual
Sacramento, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente Cancer Treatment Center
Status: Active
South San Francisco, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente Los Angeles Medical Center
Status: Active
Los Angeles, California
Contact: Michael Raymond Girvigian
Phone: 626-564-3455
Kaiser Permanente Medical Center - Santa Clara
Status: Active
Santa Clara, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente Oakland-Broadway
Status: Active
Oakland, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente San Leandro
Status: Temporarily closed to accrual
San Leandro, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Fremont
Status: Temporarily closed to accrual
Fremont, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Oakland
Status: Temporarily closed to accrual
Oakland, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Rancho Cordova Cancer Center
Status: Active
Rancho Cordova, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Redwood City
Status: Temporarily closed to accrual
Redwood City, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Richmond
Status: Temporarily closed to accrual
Richmond, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Roseville
Status: Temporarily closed to accrual
Roseville, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-San Francisco
Status: Temporarily closed to accrual
San Francisco, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-San Rafael
Status: Temporarily closed to accrual
San Rafael, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Santa Rosa
Status: Temporarily closed to accrual
Santa Rosa, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Santa Teresa-San Jose
Status: Temporarily closed to accrual
San Jose, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-South Sacramento
Status: Temporarily closed to accrual
Sacramento, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-South San Francisco
Status: Temporarily closed to accrual
South San Francisco, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Stockton
Status: Temporarily closed to accrual
Stockton, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Vallejo
Status: Temporarily closed to accrual
Vallejo, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Walnut Creek
Status: Temporarily closed to accrual
Walnut Creek, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Los Angeles County-USC Medical Center
Status: Active
Los Angeles, California
Contact: Syma Iqbal
Phone: 323-865-0451
Marin General Hospital
Status: Active
Greenbrae, California
Contact: Lloyd T. Miyawaki
Phone: 415-925-7325
Memorial Medical Center
Status: Active
Modesto, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Mills - Peninsula Hospitals
Status: Active
Burlingame, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Palo Alto Medical Foundation Health Care
Status: Active
Palo Alto, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Palo Alto Medical Foundation-Sunnyvale
Status: Active
Sunnyvale, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Providence Saint Joseph Medical Center / Disney Family Cancer Center
Status: Active
Burbank, California
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Rohnert Park Cancer Center
Status: Active
Rohnert Park, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Saint Helena Hospital
Status: Active
Saint Helena, California
Contact: David John Tate
Phone: 707-967-3698
Sharp Memorial Hospital
Status: Active
San Diego, California
Contact: Robert M. Barone
Phone: 858-939-5062 Email: cathy.wood@sharp.com
South Sacramento Cancer Center
Status: Active
Sacramento, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: Active
Auburn, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Status: Active
Cameron Park, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: Active
Roseville, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: Active
Vacaville, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter General Hospital
Status: Active
Sacramento, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Solano Medical Center / Cancer Center
Status: Active
Vallejo, California
Contact: Christopher Uwe Jones
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
The Permanente Medical Group-Roseville Radiation Oncology
Status: Active
Roseville, California
Contact: Louis Fehrenbacher
Phone: 626-564-3455
UC Irvine Health / Chao Family Comprehensive Cancer Center
Status: Active
Orange, California
Contact: Tara Elisabeth Seery
Phone: 877-827-8839 Email: ucstudy@uci.edu
UC San Diego Moores Cancer Center
Status: Temporarily closed to accrual
La Jolla, California
Contact: Loren K. Mell
Phone: 858-822-5354 Email: cancercto@ucsd.edu
USC / Norris Comprehensive Cancer Center
Status: Active
Los Angeles, California
Contact: Syma Iqbal
Phone: 323-865-0451

Colorado

Boulder Community Hospital
Status: Temporarily closed to accrual
Boulder, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Colorado Blood Cancer Institute
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Comprehensive Cancer Care and Research Institute of Colorado LLC
Status: Temporarily closed to accrual
Englewood, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Littleton Adventist Hospital
Status: Active
Littleton, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Longmont United Hospital
Status: Active
Longmont, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
McKee Medical Center
Status: Active
Loveland, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Memorial Hospital-Center
Status: Active
Colorado Springs, Colorado
Contact: Karyn Aalami Goodman
Phone: 720-848-0650
Mercy Medical Center
Status: Temporarily closed to accrual
Durango, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mountain Blue Cancer Care Center
Status: Temporarily closed to accrual
Golden, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
North Colorado Medical Center
Status: Active
Greeley, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Parker Adventist Hospital
Status: Active
Parker, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Penrose-Saint Francis Healthcare
Status: Active
Colorado Springs, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Porter Adventist Hospital
Status: Active
Denver, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Poudre Valley Hospital
Status: Active
Fort Collins, Colorado
Contact: Karyn Aalami Goodman
Phone: 720-848-0650
Presbyterian - Saint Lukes Medical Center - Health One
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers - Pueblo
Status: Temporarily closed to accrual
Pueblo, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rocky Mountain Cancer Centers-Aurora
Status: Active
Aurora, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Boulder
Status: Active
Boulder, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Greenwood Village
Status: Temporarily closed to accrual
Greenwood Village, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Lakewood
Status: Temporarily closed to accrual
Lakewood, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rocky Mountain Cancer Centers-Littleton
Status: Active
Littleton, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Longmont
Status: Temporarily closed to accrual
Longmont, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rocky Mountain Cancer Centers-Midtown
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Parker
Status: Temporarily closed to accrual
Parker, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rocky Mountain Cancer Centers-Penrose
Status: Active
Colorado Springs, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rocky Mountain Cancer Centers-Rose
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Sky Ridge
Status: Temporarily closed to accrual
Lone Tree, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Thornton
Status: Active
Thornton, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Rose Medical Center
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Saint Anthony Hospital
Status: Temporarily closed to accrual
Lakewood, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Saint Mary Corwin Medical Center
Status: Temporarily closed to accrual
Pueblo, Colorado
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
SCL Health Lutheran Medical Center
Status: Active
Wheat Ridge, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
SCL Health Saint Joseph Hospital
Status: Temporarily closed to accrual
Denver, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Sky Ridge Medical Center
Status: Temporarily closed to accrual
Lone Tree, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Swedish Medical Center
Status: Active
Englewood, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
The Medical Center of Aurora
Status: Temporarily closed to accrual
Aurora, Colorado
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
University of Colorado Cancer Center - Anschutz Cancer Pavilion
Status: Active
Aurora, Colorado
Contact: Karyn Aalami Goodman
Phone: 720-848-0650

Connecticut

Hartford Hospital
Status: Temporarily closed to accrual
Hartford, Connecticut
Contact: Andrew L. Salner
Phone: 860-545-5363
Midstate Medical Center
Status: Temporarily closed to accrual
Meriden, Connecticut
Contact: Neal B. Goldberg
Phone: 860-224-5660
Saint Vincent's Medical Center
Status: Active
Bridgeport, Connecticut
Contact: Christine Van Cott
Phone: 203-576-6329 Email: twhite@stvincents.org
The Hospital of Central Connecticut
Status: Temporarily closed to accrual
New Britain, Connecticut
Contact: Neal B. Goldberg
Phone: 860-224-5660

Delaware

Beebe Health Campus
Status: Temporarily closed to accrual
Rehoboth Beach, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Beebe Medical Center
Status: Temporarily closed to accrual
Lewes, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Christiana Care Health System-Christiana Hospital
Status: Active
Newark, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Delaware Clinical and Laboratory Physicians PA
Status: Temporarily closed to accrual
Newark, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Helen F Graham Cancer Center
Status: Active
Newark, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Medical Oncology Hematology Consultants PA
Status: Temporarily closed to accrual
Newark, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Nanticoke Memorial Hospital
Status: Temporarily closed to accrual
Seaford, Delaware
Contact: Adam Raben
Phone: 302-733-6227
Regional Hematology and Oncology PA
Status: Temporarily closed to accrual
Newark, Delaware
Contact: Adam Raben
Phone: 302-733-6227

District of Columbia

MedStar Georgetown University Hospital
Status: Temporarily closed to accrual
Washington, District of Columbia
Contact: Keith R. Unger
Phone: 202-444-2223

Florida

Florida Cancer Affiliates
Status: Temporarily closed to accrual
Trinity, Florida
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Florida Hospital Orlando
Status: Temporarily closed to accrual
Orlando, Florida
Contact: Robert James Sollaccio
Phone: 407-303-2090 Email: FH.Cancer.Research@flhosp.org
Holy Cross Hospital
Status: Temporarily closed to accrual
Fort Lauderdale, Florida
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
Jackson Memorial Hospital-Holtz Children's Hospital
Status: Active
Miami, Florida
Contact: Lorraine Portelance
Phone: 305-243-2647
Jupiter Medical Center
Status: Temporarily closed to accrual
Jupiter, Florida
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
Mayo Clinic in Florida
Status: Temporarily closed to accrual
Jacksonville, Florida
Contact: Michael G. Haddock
Phone: 855-776-0015
Mount Sinai Medical Center
Status: Temporarily closed to accrual
Miami Beach, Florida
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
UF Cancer Center at Orlando Health
Status: Active
Orlando, Florida
Contact: Daniel Joseph Buchholz
Phone: 321-841-7246 Email: CancerClinicalTrials@orlandohealth.com
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Status: Active
Deerfield Beach, Florida
Contact: Lorraine Portelance
Phone: 305-243-2647
University of Florida
Status: Active
Gainesville, Florida
Contact: Thomas J. George
Phone: 352-273-8675 Email: trials@cancer.ufl.edu
University of Miami Miller School of Medicine-Sylvester Cancer Center
Status: Active
Miami, Florida
Contact: Lorraine Portelance
Phone: 305-243-2647

Georgia

Emory University / Winship Cancer Institute
Status: Active
Atlanta, Georgia
Contact: Bassel F. El-Rayes
Phone: 404-778-1868
Emory University Hospital Midtown
Status: Active
Atlanta, Georgia
Contact: Bassel F. El-Rayes
Phone: 404-778-1868
Grady Health System
Status: Temporarily closed to accrual
Atlanta, Georgia
Contact: Jerome Carl Landry
Phone: 404-489-9164
John B Amos Cancer Center
Status: Temporarily closed to accrual
Columbus, Georgia
Contact: Andrew W. Pippas
Phone: 706-660-6404
Lewis Cancer and Research Pavilion at Saint Joseph's / Candler
Status: Active
Savannah, Georgia
Contact: John A. Pablo
Phone: 912-819-5704
Memorial University Medical Center
Status: Active
Savannah, Georgia
Contact: Aaron Watson Pederson
Phone: 912-350-8568
Northeast Georgia Medical Center-Gainesville
Status: Active
Gainesville, Georgia
Contact: Frank Greer Lake
Phone: 770-219-8800 Email: cancerpatient.navigator@nghs.com
Saint Joseph's Hospital of Atlanta
Status: Active
Atlanta, Georgia
Contact: Bassel F. El-Rayes
Phone: 404-778-1868

Hawaii

Hawaii Cancer Care Inc-Liliha
Status: Active
Honolulu, Hawaii
Contact: Richard Y. Lee
Phone: 808-547-6011
Queen's Medical Center
Status: Active
Honolulu, Hawaii
Contact: Richard Y. Lee
Phone: 808-547-6011
The Cancer Center of Hawaii-Leeward
Status: Temporarily closed to accrual
Ewa Beach, Hawaii
Contact: Richard Y. Lee
Phone: 808-547-6011
The Cancer Center of Hawaii-Liliha
Status: Active
Honolulu, Hawaii
Contact: Richard Y. Lee
Phone: 808-547-6011
University of Hawaii Cancer Center
Status: Active
Honolulu, Hawaii
Contact: Richard Y. Lee
Phone: 808-547-6011

Idaho

Saint Joseph Regional Medical Center
Status: Temporarily closed to accrual
Lewiston, Idaho
Contact: John A. Keech
Phone: 253-403-2394
Saint Luke's Mountain States Tumor Institute
Status: Active
Boise, Idaho
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Luke's Mountain States Tumor Institute - Fruitland
Status: Active
Fruitland, Idaho
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Luke's Mountain States Tumor Institute - Meridian
Status: Active
Meridian, Idaho
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Luke's Mountain States Tumor Institute - Nampa
Status: Active
Nampa, Idaho
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Luke's Mountain States Tumor Institute-Twin Falls
Status: Active
Twin Falls, Idaho
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org

Illinois

Carle Cancer Center
Status: Active
Urbana, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Carle on Vermilion
Status: Temporarily closed to accrual
Danville, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Carle Physician Group-Effingham
Status: Temporarily closed to accrual
Effingham, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Carle Physician Group-Mattoon / Charleston
Status: Temporarily closed to accrual
Mattoon, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Community Cancer Center Foundation
Status: Temporarily closed to accrual
Normal, Illinois
Contact: Nguyet Anh Le-Lindqwister
Phone: 800-793-2262
Decatur Memorial Hospital
Status: Active
Decatur, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Edward Hospital / Cancer Center
Status: Active
Naperville, Illinois
Contact: Alexander Hantel
Phone: 630-646-6075
Edward Hospital / Cancer Center?Plainfield
Status: Active
Plainfield, Illinois
Contact: Alexander Hantel
Phone: 630-646-6075
Good Samaritan Regional Health Center
Status: Temporarily closed to accrual
Mount Vernon, Illinois
Contact: Jay W. Carlson
Phone: 800-821-7532
Illinois CancerCare-Bloomington
Status: Temporarily closed to accrual
Bloomington, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Canton
Status: Temporarily closed to accrual
Canton, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Carthage
Status: Temporarily closed to accrual
Carthage, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Eureka
Status: Temporarily closed to accrual
Eureka, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Galesburg
Status: Temporarily closed to accrual
Galesburg, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Kewanee Clinic
Status: Temporarily closed to accrual
Kewanee, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Macomb
Status: Temporarily closed to accrual
Macomb, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Ottawa Clinic
Status: Temporarily closed to accrual
Ottawa, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Pekin
Status: Temporarily closed to accrual
Pekin, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Peoria
Status: Temporarily closed to accrual
Peoria, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Peru
Status: Temporarily closed to accrual
Peru, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Illinois CancerCare-Princeton
Status: Temporarily closed to accrual
Princeton, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Ingalls Memorial Hospital
Status: Active
Harvey, Illinois
Contact: Sulochana D. Yalavarthi
Phone: 708-915-4673 Email: clinicaltrials@ingalls.org
John H Stroger Jr Hospital of Cook County
Status: Active
Chicago, Illinois
Contact: Thomas E. Lad
Phone: 312-864-6000
Loyola University Medical Center
Status: Active
Maywood, Illinois
Contact: William Small
Phone: 708-226-4357
Memorial Medical Center
Status: Active
Springfield, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Methodist Medical Center of Illinois
Status: Active
Peoria, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Northwest Community Hospital
Status: Active
Arlington Heights, Illinois
Contact: Stephen Schaeffer Nigh
Phone: 847-618-4968
Northwestern Medicine Cancer Center Delnor
Status: Active
Geneva, Illinois
Contact: Christopher M. George
Phone: 630-315-1918 Email: Claudine.Gamster@CadenceHealth.org
Northwestern Medicine Cancer Center Warrenville
Status: Active
Warrenville, Illinois
Contact: Christopher M. George
Phone: 630-315-1918 Email: Claudine.Gamster@CadenceHealth.org
Northwestern University
Status: Active
Chicago, Illinois
Contact: John Patrick Hayes
Phone: 312-695-1301 Email: cancer@northwestern.edu
OSF Saint Francis Medical Center
Status: Active
Peoria, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Status: Active
Pekin, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Status: Active
Peoria, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Presence Resurrection Medical Center
Status: Temporarily closed to accrual
Chicago, Illinois
Contact: Christopher G. Rose
Phone: 773-792-5116
Presence Saint Mary's Hospital
Status: Temporarily closed to accrual
Kankakee, Illinois
Contact: Sylvia V. Velinova Falls
Phone: 815-937-8780
Radiation Oncology of Northern Illinois
Status: Temporarily closed to accrual
Ottawa, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Rush - Copley Medical Center
Status: Temporarily closed to accrual
Aurora, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Rush University Medical Center
Status: Active
Chicago, Illinois
Contact: Ross Allen Abrams
Phone: 312-942-5498 Email: clinical_trials@rush.edu
Rush-Copley Healthcare Center
Status: Temporarily closed to accrual
Yorkville, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
Saint John's Hospital
Status: Active
Springfield, Illinois
Contact: Laurent Brard
Phone: 217-525-5666 Email: diana.weyhenmeyer@st-johns.org
Saint Joseph Medical Center
Status: Temporarily closed to accrual
Bloomington, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
The Carle Foundation Hospital
Status: Temporarily closed to accrual
Urbana, Illinois
Contact: Kalika Prasad Sarma
Phone: 800-446-5532
University of Chicago Comprehensive Cancer Center
Status: Temporarily closed to accrual
Chicago, Illinois
Contact: Stanley Lawrence Liauw
Phone: 773-834-7424
University of Illinois
Status: Active
Chicago, Illinois
Contact: Neeta Kiran Venepalli
Phone: 312-355-3046
Valley Radiation Oncology
Status: Active
Peru, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Western Illinois Cancer Treatment Center
Status: Temporarily closed to accrual
Galesburg, Illinois
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org

Indiana

Community Howard Regional Health
Status: Temporarily closed to accrual
Kokomo, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Elkhart Clinic
Status: Temporarily closed to accrual
Elkhart, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Elkhart General Hospital
Status: Temporarily closed to accrual
Elkhart, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Franciscan Saint Francis Health-Beech Grove
Status: Temporarily closed to accrual
Beech Grove, Indiana
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Goshen Center for Cancer Care
Status: Active
Goshen, Indiana
Contact: James A. Wheeler
Phone: 574-364-2973 Email: cccois@goshenhealth.com
IU Health La Porte Hospital
Status: Temporarily closed to accrual
La Porte, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Memorial Hospital of South Bend
Status: Active
South Bend, Indiana
Contact: David Alan Hornback
Phone: 800-284-7370
Memorial Regional Cancer Center Day Road
Status: Active
Mishawaka, Indiana
Contact: David Alan Hornback
Phone: 800-284-7370
Michiana Hematology Oncology PC-Elkhart
Status: Temporarily closed to accrual
Elkhart, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Michiana Hematology Oncology PC-Mishawaka
Status: Temporarily closed to accrual
Mishawaka, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Michiana Hematology Oncology PC-Plymouth
Status: Temporarily closed to accrual
Plymouth, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Michiana Hematology Oncology PC-South Bend
Status: Temporarily closed to accrual
South Bend, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Michiana Hematology Oncology PC-Westville
Status: Temporarily closed to accrual
Westville, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Northern Indiana Cancer Research Consortium
Status: Active
South Bend, Indiana
Contact: Robin T. Zon
Phone: 574-234-5123
Parkview Hospital Randallia
Status: Active
Fort Wayne, Indiana
Contact: Brian K. Chang
Phone: 260-373-8888 Email: parkviewresearch@parkview.com
Radiation Oncology Associates PC
Status: Active
Fort Wayne, Indiana
Contact: Brian K. Chang
Phone: 260-373-8888 Email: parkviewresearch@parkview.com
Reid Health
Status: Temporarily closed to accrual
Richmond, Indiana
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Saint Joseph Regional Medical Center-Mishawaka
Status: Temporarily closed to accrual
Mishawaka, Indiana
Contact: Robin T. Zon
Phone: 574-237-1328
Woodland Cancer Care Center
Status: Temporarily closed to accrual
Michigan City, Indiana
Contact: Kalika Prasad Sarma
Phone: 800-446-5532

Iowa

Iowa Lutheran Hospital
Status: Temporarily closed to accrual
Des Moines, Iowa
Contact: Robert J. Behrens
Phone: 515-282-2921
Iowa Methodist Medical Center
Status: Active
Des Moines, Iowa
Contact: Robert J. Behrens
Phone: 515-282-2921
Medical Oncology and Hematology Associates-Des Moines
Status: Temporarily closed to accrual
Des Moines, Iowa
Contact: Robert J. Behrens
Phone: 515-282-2921
Medical Oncology and Hematology Associates-Laurel
Status: Active
Des Moines, Iowa
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Medical Oncology and Hematology Associates-West Des Moines
Status: Temporarily closed to accrual
Clive, Iowa
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mercy Cancer Center-West Lakes
Status: Active
Clive, Iowa
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mercy Medical Center - Des Moines
Status: Active
Des Moines, Iowa
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Mercy Medical Center-West Lakes
Status: Temporarily closed to accrual
West Des Moines, Iowa
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Methodist West Hospital
Status: Temporarily closed to accrual
West Des Moines, Iowa
Contact: Robert J. Behrens
Phone: 515-282-2921
Siouxland Regional Cancer Center
Status: Active
Sioux City, Iowa
Contact: Donald B. Wender
Phone: 712-252-0088

Kansas

Associates In Womens Health
Status: Temporarily closed to accrual
Wichita, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Chanute
Status: Temporarily closed to accrual
Chanute, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Dodge City
Status: Temporarily closed to accrual
Dodge City, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - El Dorado
Status: Temporarily closed to accrual
El Dorado, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Fort Scott
Status: Temporarily closed to accrual
Fort Scott, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - McPherson
Status: Temporarily closed to accrual
McPherson, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Newton
Status: Temporarily closed to accrual
Newton, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Parsons
Status: Temporarily closed to accrual
Parsons, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Pratt
Status: Temporarily closed to accrual
Pratt, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Salina
Status: Temporarily closed to accrual
Salina, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Wellington
Status: Temporarily closed to accrual
Wellington, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Wichita
Status: Temporarily closed to accrual
Wichita, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Winfield
Status: Temporarily closed to accrual
Winfield, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Independence
Status: Temporarily closed to accrual
Independence, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Kingman
Status: Temporarily closed to accrual
Kingman, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Liberal
Status: Temporarily closed to accrual
Liberal, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Manhattan
Status: Temporarily closed to accrual
Manhattan, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Wichita Medical Arts Tower
Status: Temporarily closed to accrual
Wichita, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cotton O'Neil Cancer Center / Stormont Vail Health
Status: Temporarily closed to accrual
Topeka, Kansas
Contact: David E. Einspahr
Phone: 785-270-4963
Lawrence Memorial Hospital
Status: Temporarily closed to accrual
Lawrence, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Menorah Medical Center
Status: Temporarily closed to accrual
Overland Park, Kansas
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Luke's South Hospital
Status: Temporarily closed to accrual
Overland Park, Kansas
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Via Christi Regional Medical Center
Status: Active
Wichita, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Wesley Medical Center
Status: Active
Wichita, Kansas
Contact: Shaker R. Dakhil
Phone: 316-268-5374

Kentucky

Baptist Health Lexington
Status: Active
Lexington, Kentucky
Contact: Firas B. Badin
Phone: 859-260-6425
University of Kentucky / Markey Cancer Center
Status: Active
Lexington, Kentucky
Contact: Mahesh Ravindra Kudrimoti
Phone: 859-257-3379

Louisiana

Ochsner Medical Center Jefferson
Status: Active
New Orleans, Louisiana
Contact: Roland B. Hawkins
Phone: 888-562-4763
Tulane University Health Sciences Center
Status: Active
New Orleans, Louisiana
Contact: William Russell Robinson
Phone: 504-988-6121

Maryland

Peninsula Regional Medical Center
Status: Temporarily closed to accrual
Salisbury, Maryland
Contact: John Romeo Mansueti
Phone: 866-922-6237
Saint Agnes Hospital
Status: Active
Baltimore, Maryland
Contact: Richard S. Hudes
Phone: 410-368-2910
Sinai Hospital of Baltimore
Status: Active
Baltimore, Maryland
Contact: Mayer Gorbaty
Phone: 410-601-4673 Email: cancerinstitute@lifebridgehealth.org
University of Maryland / Greenebaum Cancer Center
Status: Active
Baltimore, Maryland
Contact: William Frank Regine
Phone: 800-888-8823

Massachusetts

Baystate Medical Center
Status: Active
Springfield, Massachusetts
Contact: Seth A. Kaufman
Phone: 413-794-9338
Berkshire Hematology Oncology PC
Status: Temporarily closed to accrual
Pittsfield, Massachusetts
Contact: Harvey Zimbler
Phone: 413-496-8205 Email: ggero@bhs1.org
Boston Medical Center
Status: Active
Boston, Massachusetts
Contact: Minh Tam Truong
Phone: 617-638-8265
Lahey Hospital and Medical Center
Status: Active
Burlington, Massachusetts
Contact: Keith Ellis Stuart
Phone: 781-744-8027
Saint Anne's Hospital
Status: Active
Fall River, Massachusetts
Contact: Raymond L. Dugal
Phone: 508-674-5600ext2515

Michigan

Borgess Medical Center
Status: Temporarily closed to accrual
Kalamazoo, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Bronson Methodist Hospital
Status: Temporarily closed to accrual
Kalamazoo, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Green Bay Oncology - Escanaba
Status: Temporarily closed to accrual
Escanaba, Michigan
Contact: Eva N. Christensen
Phone: 920-433-8889
Green Bay Oncology - Iron Mountain
Status: Temporarily closed to accrual
Iron Mountain, Michigan
Contact: Eva N. Christensen
Phone: 920-433-8889
Henry Ford Cancer Institute¿Downriver
Status: Active
Brownstown, Michigan
Contact: Eleanor M. Walker
Phone: 313-916-1784 Email: ewalker1@hfhs.org
Henry Ford Hospital
Status: Active
Detroit, Michigan
Contact: Eleanor M. Walker
Phone: 313-916-1784 Email: ewalker1@hfhs.org
Henry Ford Macomb Hospital-Clinton Township
Status: Active
Clinton Township, Michigan
Contact: Eleanor M. Walker
Phone: 313-916-1784 Email: ewalker1@hfhs.org
Henry Ford West Bloomfield Hospital
Status: Active
West Bloomfield, Michigan
Contact: Eleanor M. Walker
Phone: 313-916-1784 Email: ewalker1@hfhs.org
Hickman Cancer Center
Status: Active
Adrian, Michigan
Contact: Rex B. Mowat
Phone: 800-444-3561
Huron Valley-Sinai Hospital
Status: Temporarily closed to accrual
Commerce, Michigan
Contact: Michael Matthew Dominello
Phone: 313-576-9363
Lakeland Hospital
Status: Temporarily closed to accrual
Saint Joseph, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Marie Yeager Cancer Center
Status: Temporarily closed to accrual
Saint Joseph, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Mercy Health Mercy Campus
Status: Active
Muskegon, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Mercy Health Saint Mary's
Status: Active
Grand Rapids, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Saint John Hospital and Medical Center
Status: Active
Detroit, Michigan
Contact: Samir Narayan
Phone: 734-712-4673
Saint John Macomb-Oakland Hospital
Status: Active
Warren, Michigan
Contact: Samir Narayan
Phone: 734-712-4673
Saint Joseph Mercy Hospital
Status: Active
Ann Arbor, Michigan
Contact: Samir Narayan
Phone: 734-712-4673
Saint Joseph Mercy Oakland
Status: Active
Pontiac, Michigan
Contact: Samir Narayan
Phone: 734-712-4673
Saint Mary Mercy Hospital
Status: Active
Livonia, Michigan
Contact: Samir Narayan
Phone: 734-712-4673
Spectrum Health at Butterworth Campus
Status: Active
Grand Rapids, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Toledo Clinic Cancer Centers-Monroe
Status: Temporarily closed to accrual
Monroe, Michigan
Contact: Rex B. Mowat
Phone: 800-444-3561
University of Michigan Comprehensive Cancer Center
Status: Temporarily closed to accrual
Ann Arbor, Michigan
Contact: Mary U. Feng
Phone: 877-827-3222
Wayne State University / Karmanos Cancer Institute
Status: Active
Detroit, Michigan
Contact: Michael Matthew Dominello
Phone: 313-576-9363
Weisberg Cancer Treatment Center
Status: Active
Farmington Hills, Michigan
Contact: Michael Matthew Dominello
Phone: 313-576-9363
West Michigan Cancer Center
Status: Active
Kalamazoo, Michigan
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
William Beaumont Hospital - Troy
Status: Active
Troy, Michigan
Contact: Laura M. Nadeau
Phone: 248-551-7695
William Beaumont Hospital-Royal Oak
Status: Active
Royal Oak, Michigan
Contact: Laura M. Nadeau
Phone: 248-551-7695

Minnesota

Abbott-Northwestern Hospital
Status: Active
Minneapolis, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Fairview Ridges Hospital
Status: Temporarily closed to accrual
Burnsville, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Fairview-Southdale Hospital
Status: Temporarily closed to accrual
Edina, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Hennepin County Medical Center
Status: Temporarily closed to accrual
Minneapolis, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Mayo Clinic
Status: Active
Rochester, Minnesota
Contact: Michael G. Haddock
Phone: 855-776-0015
Mercy Hospital
Status: Temporarily closed to accrual
Coon Rapids, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Minnesota Oncology Hematology PA-Maplewood
Status: Active
Maplewood, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
North Memorial Medical Health Center
Status: Active
Robbinsdale, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Park Nicollet Clinic - Saint Louis Park
Status: Active
Saint Louis Park, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Regions Hospital
Status: Active
Saint Paul, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Rice Memorial Hospital
Status: Active
Willmar, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Ridgeview Medical Center
Status: Temporarily closed to accrual
Waconia, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Saint John's Hospital - Healtheast
Status: Temporarily closed to accrual
Maplewood, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
United Hospital
Status: Active
Saint Paul, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Unity Hospital
Status: Active
Fridley, Minnesota
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com

Missouri

Barnes-Jewish West County Hospital
Status: Active
Creve Coeur, Missouri
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@ccadmin.wustl.edu
Capital Region Medical Center-Goldschmidt Cancer Center
Status: Temporarily closed to accrual
Jefferson City, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Centerpoint Medical Center LLC
Status: Temporarily closed to accrual
Independence, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Central Care Cancer Center-Carrie J Babb Cancer Center
Status: Temporarily closed to accrual
Bolivar, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
CoxHealth Cancer Center
Status: Temporarily closed to accrual
Branson, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
CoxHealth South Hospital
Status: Active
Springfield, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Delbert Day Cancer Institute at PCRMC
Status: Active
Rolla, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Freeman Health System
Status: Temporarily closed to accrual
Joplin, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Heartland Hematology and Oncology Associates Incorporated
Status: Temporarily closed to accrual
Kansas City, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Heartland Regional Medical Center
Status: Temporarily closed to accrual
Saint Joseph, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Liberty Radiation Oncology Center
Status: Temporarily closed to accrual
Liberty, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Mercy Hospital Saint Louis
Status: Temporarily closed to accrual
Saint Louis, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Mercy Hospital Springfield
Status: Active
Springfield, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Mercy Hospital-Joplin
Status: Temporarily closed to accrual
Joplin, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Missouri Baptist Medical Center
Status: Active
Saint Louis, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Missouri Baptist Outpatient Center-Sunset Hills
Status: Temporarily closed to accrual
Sunset Hills, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Missouri Baptist Sullivan Hospital
Status: Temporarily closed to accrual
Sullivan, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Parkland Health Center-Bonne Terre
Status: Temporarily closed to accrual
Bonne Terre, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Research Medical Center
Status: Active
Kansas City, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Francis Medical Center
Status: Temporarily closed to accrual
Cape Girardeau, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Saint John's Clinic-Rolla-Cancer and Hematology
Status: Temporarily closed to accrual
Rolla, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Saint Louis Cancer and Breast Institute-South City
Status: Temporarily closed to accrual
Saint Louis, Missouri
Contact: Jay W. Carlson
Phone: 800-821-7532
Saint Luke's East - Lee's Summit
Status: Temporarily closed to accrual
Lee's Summit, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Luke's Hospital of Kansas City
Status: Active
Kansas City, Missouri
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Sainte Genevieve County Memorial Hospital
Status: Temporarily closed to accrual
Sainte Genevieve, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Siteman Cancer Center - Saint Peters
Status: Active
Saint Peters, Missouri
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@ccadmin.wustl.edu
Siteman Cancer Center-South County
Status: Temporarily closed to accrual
Saint Louis, Missouri
Contact: Jeffrey Robert Olsen
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Southeast Cancer Center
Status: Active
Cape Girardeau, Missouri
Contact: James Lloyd Wade
Phone: 217-876-4740 Email: kcheek@dmhhs.org
Washington University School of Medicine
Status: Active
Saint Louis, Missouri
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@ccadmin.wustl.edu

Montana

Billings Clinic Cancer Center
Status: Active
Billings, Montana
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Kalispell Regional Medical Center
Status: Active
Kalispell, Montana
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Saint James Community Hospital and Cancer Treatment Center
Status: Temporarily closed to accrual
Butte, Montana
Contact: Benjamin T. Marchello
Phone: 800-648-6274
Saint Patrick Hospital - Community Hospital
Status: Temporarily closed to accrual
Missoula, Montana
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Vincent Healthcare
Status: Temporarily closed to accrual
Billings, Montana
Contact: Benjamin T. Marchello
Phone: 800-648-6274

Nebraska

Alegent Health Bergan Mercy Medical Center
Status: Active
Omaha, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Alegent Health Immanuel Medical Center
Status: Temporarily closed to accrual
Omaha, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Alegent Health Lakeside Hospital
Status: Active
Omaha, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
CHI Health Good Samaritan
Status: Active
Kearney, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
CHI Health Saint Francis
Status: Active
Grand Island, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Creighton University Medical Center
Status: Temporarily closed to accrual
Omaha, Nebraska
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Nebraska Cancer Research Center
Status: Temporarily closed to accrual
Lincoln, Nebraska
Contact: Gamini S. Soori
Phone: 402-393-3110
Nebraska Methodist Hospital
Status: Active
Omaha, Nebraska
Contact: Tien-Shew William Huang
Phone: 402-354-5144
University of Nebraska Medical Center
Status: Active
Omaha, Nebraska
Contact: Chi Lin
Phone: 402-559-8555 Email: llarson@unmc.edu

Nevada

21st Century Oncology
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
21st Century Oncology - Fort Apache
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
21st Century Oncology - Henderson
Status: Temporarily closed to accrual
Henderson, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
21st Century Oncology - Vegas Tenaya
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Henderson
Status: Temporarily closed to accrual
Henderson, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Shadow
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer and Blood Specialists-Tenaya
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Cancer Therapy and Integrative Medicine
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Central Valley
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Henderson
Status: Active
Henderson, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada - Northwest
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: Temporarily closed to accrual
Henderson, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Comprehensive Cancer Centers of Nevada-Summerlin
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Las Vegas Cancer Center-Henderson
Status: Temporarily closed to accrual
Henderson, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Las Vegas Cancer Center-Medical Center
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Nevada Cancer Research Foundation CCOP
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Nevada Cancer Specialists-Fort Apache
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Radiation Oncology Centers of Nevada Central
Status: Active
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Radiation Oncology Centers of Nevada Southeast
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
Renown Regional Medical Center
Status: Active
Reno, Nevada
Contact: Michael Chandler Hardacre
Phone: 775-982-4400
Summerlin Hospital Medical Center
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013
University Medical Center of Southern Nevada
Status: Temporarily closed to accrual
Las Vegas, Nevada
Contact: John Allan Ellerton
Phone: 702-384-0013

New Hampshire

Elliot Hospital
Status: Active
Manchester, New Hampshire
Contact: Brian Robert Knab
Phone: 603-663-1800

New Jersey

Cooper Hospital University Medical Center
Status: Temporarily closed to accrual
Camden, New Jersey
Contact: Ashish Bharat Patel
Phone: 856-325-6757
MD Anderson Cancer Center at Cooper-Voorhees
Status: Temporarily closed to accrual
Voorhees, New Jersey
Contact: Ashish Bharat Patel
Phone: 856-325-6757
Memorial Sloan Kettering Cancer Center at Basking Ridge
Status: Active
Basking Ridge, New Jersey
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Memorial Sloan Kettering Monmouth Monmouth
Status: Active
Middletown, New Jersey
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Newark Beth Israel Medical Center
Status: Active
Newark, New Jersey
Contact: Charles S. Cathcart
Phone: 973-926-7230
Rutgers New Jersey Medical School
Status: Temporarily closed to accrual
Newark, New Jersey
Contact: Sabin Bhagwan Motwani
Phone: 732-235-8675
Saint Barnabas Medical Center
Status: Active
Livingston, New Jersey
Contact: Delia Radovich
Phone: 973-322-2470
Sparta Cancer Treatment Center
Status: Active
Sparta, New Jersey
Contact: Adam Craig Berger
Phone: 215-955-6084
The Valley Hospital-Luckow Pavilion
Status: Active
Paramus, New Jersey
Contact: Thomas J. Rakowski
Phone: 201-634-5792
Valley Health System-Hematology / Oncology
Status: Active
Westwood, New Jersey
Contact: Thomas J. Rakowski
Phone: 201-634-5792
Valley Hospital
Status: Active
Ridgewood, New Jersey
Contact: Thomas J. Rakowski
Phone: 201-634-5792
Virtua Memorial
Status: Temporarily closed to accrual
Mount Holly, New Jersey
Contact: Lemuel S. Ariaratnam
Phone: 609-914-6762
Virtua Voorhees
Status: Temporarily closed to accrual
Voorhees, New Jersey
Contact: Lemuel S. Ariaratnam
Phone: 609-914-6762

New York

Glens Falls Hospital
Status: Active
Glens Falls, New York
Contact: John Patrick Stoutenburg
Phone: 518-926-6700
Highland Hospital
Status: Active
Rochester, New York
Contact: Yuhchyau Chen
Phone: 585-275-5830
Laura and Isaac Perlmutter Cancer Center at NYU Langone
Status: Active
New York, New York
Contact: Kevin Lee Du
Phone: 212-263-4434 Email: prmc.coordinator@nyumc.org
Long Island Jewish Medical Center
Status: Temporarily closed to accrual
New Hyde Park, New York
Contact: Beatrice F. Bloom
Phone: 516-734-8954
Maimonides Medical Center
Status: Active
Brooklyn, New York
Contact: Bernadine Donahue
Phone: 718-765-2500
Memorial Sloan Kettering Commack
Status: Active
Commack, New York
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Memorial Sloan Kettering Rockville Centre
Status: Active
Rockville Centre, New York
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Memorial Sloan Kettering Sleepy Hollow
Status: Temporarily closed to accrual
Sleepy Hollow, New York
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Memorial Sloan Kettering Westchester
Status: Active
West Harrison, New York
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Memorial Sloan-Kettering Cancer Center
Status: Temporarily closed to accrual
New York, New York
Contact: Karyn Aalami Goodman
Phone: 720-848-0650
New York Oncology Hematology PC - Albany
Status: Temporarily closed to accrual
Albany, New York
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Sands Cancer Center
Status: Temporarily closed to accrual
Canandiaqua, New York
Contact: Yuhchyau Chen
Phone: 585-275-5830
University of Rochester
Status: Active
Rochester, New York
Contact: Yuhchyau Chen
Phone: 585-275-5830

North Carolina

Carolinas HealthCare System NorthEast
Status: Temporarily closed to accrual
Concord, North Carolina
Contact: John Stuart Salmon
Phone: 800-804-9376
Carolinas Medical Center / Levine Cancer Institute
Status: Temporarily closed to accrual
Charlotte, North Carolina
Contact: John Stuart Salmon
Phone: 800-804-9376
East Carolina University
Status: Active
Greenville, North Carolina
Contact: Pamela Ann Lepera
Phone: 252-744-2161
Kinston Medical Specialists PA
Status: Active
Kinston, North Carolina
Contact: Peter Robins Watson
Phone: 252-559-2200
Matthews Radiation Oncology Center
Status: Active
Matthews, North Carolina
Contact: Nasfat Shehadeh
Phone: 704-384-5369
Novant Health Presbyterian Medical Center
Status: Temporarily closed to accrual
Charlotte, North Carolina
Contact: Nasfat Shehadeh
Phone: 704-384-5369
Park Ridge Hospital Breast Health Center
Status: Temporarily closed to accrual
Hendersonville, North Carolina
Contact: Raymond Thertulien
Phone: 855-774-5433
Rex Cancer Center
Status: Active
Raleigh, North Carolina
Contact: Justin Ja-Li Wu
Phone: 919-784-7209

Ohio

Adena Regional Medical Center
Status: Temporarily closed to accrual
Chillicothe, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Akron General Medical Center
Status: Active
Akron, Ohio
Contact: Mitchel L. Fromm
Phone: 330-344-6348
Atrium Medical Center-Middletown Regional Hospital
Status: Temporarily closed to accrual
Franklin, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Bethesda North Hospital
Status: Active
Cincinnati, Ohio
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Blanchard Valley Hospital
Status: Temporarily closed to accrual
Findlay, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Cleveland Clinic Cancer Center / Fairview Hospital
Status: Active
Cleveland, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Cleveland Clinic Cancer Center Independence
Status: Active
Independence, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Cleveland Clinic Cancer Center Strongsville
Status: Active
Strongsville, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Cleveland Clinic Foundation
Status: Active
Cleveland, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Cleveland Clinic Wooster Family Health and Surgery Center
Status: Active
Wooster, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Columbus Oncology and Hematology Associates Inc
Status: Temporarily closed to accrual
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Delaware Health Center-Grady Cancer Center
Status: Temporarily closed to accrual
Delaware, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Delaware Radiation Oncology
Status: Temporarily closed to accrual
Delaware, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Doctors Hospital
Status: Temporarily closed to accrual
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Fairfield Medical Center
Status: Temporarily closed to accrual
Lancaster, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Flower Hospital
Status: Active
Sylvania, Ohio
Contact: Jeffrey Henry Muler
Phone: 419-824-1842
Genesis Healthcare System Cancer Care Center
Status: Temporarily closed to accrual
Zanesville, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Good Samaritan Hospital - Cincinnati
Status: Active
Cincinnati, Ohio
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Good Samaritan Hospital - Dayton
Status: Temporarily closed to accrual
Dayton, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Grady Memorial Hospital
Status: Temporarily closed to accrual
Delaware, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Grandview Hospital
Status: Temporarily closed to accrual
Dayton, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Grant Medical Center
Status: Active
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Greene Memorial Hospital
Status: Temporarily closed to accrual
Xenia, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Hillcrest Hospital Cancer Center
Status: Active
Mayfield Heights, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Kettering Medical Center
Status: Temporarily closed to accrual
Kettering, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Knox Community Hospital
Status: Temporarily closed to accrual
Mount Vernon, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Lancaster Radiation Oncology
Status: Temporarily closed to accrual
Lancaster, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Licking Memorial Hospital
Status: Temporarily closed to accrual
Newark, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Marietta Memorial Hospital
Status: Temporarily closed to accrual
Marietta, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Mercy Saint Anne Hospital
Status: Temporarily closed to accrual
Toledo, Ohio
Contact: Rex B. Mowat
Phone: 800-444-3561
MetroHealth Medical Center
Status: Active
Cleveland, Ohio
Contact: Bruce J. Averbook
Phone: 216-778-8526 Email: kbauchens@metrohealth.org
Miami Valley Hospital
Status: Temporarily closed to accrual
Dayton, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Mount Carmel Health Center West
Status: Temporarily closed to accrual
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Newark Radiation Oncology
Status: Temporarily closed to accrual
Newark, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
North Coast Cancer Care
Status: Active
Sandusky, Ohio
Contact: Andrew D. Vassil
Phone: 866-223-8100
Riverside Methodist Hospital
Status: Active
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Saint Ann's Hospital
Status: Temporarily closed to accrual
Westerville, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Saint Charles Hospital
Status: Temporarily closed to accrual
Oregon, Ohio
Contact: Rex B. Mowat
Phone: 800-444-3561
Samaritan North Health Center
Status: Temporarily closed to accrual
Dayton, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Southern Ohio Medical Center
Status: Temporarily closed to accrual
Portsmouth, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Springfield Regional Medical Center
Status: Temporarily closed to accrual
Springfield, Ohio
Contact: John Philip Kuebler
Phone: 614-488-2745 Email: sheree@columbusccop.org
Strecker Cancer Center-Belpre
Status: Temporarily closed to accrual
Belpre, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Summa Akron City Hospital / Cooper Cancer Center
Status: Active
Akron, Ohio
Contact: Desiree E. Doncals
Phone: 330-375-6101
Summa Barberton Hospital
Status: Active
Barberton, Ohio
Contact: Desiree E. Doncals
Phone: 330-375-6101
Summa Health Center at Lake Medina
Status: Active
Medina, Ohio
Contact: Desiree E. Doncals
Phone: 330-375-6101
The Mark H Zangmeister Center
Status: Active
Columbus, Ohio
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Toledo Clinic Cancer Centers-Maumee
Status: Active
Maumee, Ohio
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Clinic Cancer Centers-Toledo
Status: Temporarily closed to accrual
Toledo, Ohio
Contact: Rex B. Mowat
Phone: 800-444-3561
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Status: Temporarily closed to accrual
Maumee, Ohio
Contact: Rex B. Mowat
Phone: 800-444-3561
University of Cincinnati / Barrett Cancer Center
Status: Temporarily closed to accrual
Cincinnati, Ohio
Contact: Kevin Patrick Redmond
Phone: 513-558-4553 Email: uchealthnews@uc.edu
University of Toledo
Status: Active
Toledo, Ohio
Contact: Krishna Reddy
Phone: 419-383-6583
University Pointe
Status: Temporarily closed to accrual
West Chester, Ohio
Contact: Kevin Patrick Redmond
Phone: 513-558-4553 Email: uchealthnews@uc.edu
Upper Valley Medical Center
Status: Temporarily closed to accrual
Troy, Ohio
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu

Oklahoma

University of Oklahoma Health Sciences Center
Status: Active
Oklahoma City, Oklahoma
Contact: Terence S. Herman
Phone: 405-271-8777 Email: ou-clinical-trials@ouhsc.edu

Oregon

Clackamas Radiation Oncology Center
Status: Active
Clackamas, Oregon
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Legacy Good Samaritan Hospital and Medical Center
Status: Active
Portland, Oregon
Contact: Andrew Y. Kee
Phone: 800-220-4937 Email: cancer@lhs.org
Legacy Mount Hood Medical Center
Status: Active
Gresham, Oregon
Contact: Andrew Y. Kee
Phone: 800-220-4937 Email: cancer@lhs.org
Mid-Columbia Medical Center / Celilo Cancer Center
Status: Temporarily closed to accrual
The Dalles, Oregon
Contact: Keith J. Stelzer
Phone: 541-296-7585
Providence Milwaukie Hospital
Status: Temporarily closed to accrual
Milwaukie, Oregon
Contact: Matthew C. Solhjem
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Providence Newberg Medical Center
Status: Temporarily closed to accrual
Newberg, Oregon
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Portland Medical Center
Status: Active
Portland, Oregon
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Saint Vincent Medical Center
Status: Active
Portland, Oregon
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Willamette Falls Medical Center
Status: Temporarily closed to accrual
Oregon City, Oregon
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org

Pennsylvania

Abington Memorial Hospital
Status: Active
Abington, Pennsylvania
Contact: Wayne H. Pinover
Phone: 215-481-2402
Adams Cancer Center
Status: Temporarily closed to accrual
Gettysburg, Pennsylvania
Contact: Amit B. Shah
Phone: 877-441-7957
Aria Health-Torresdale Campus
Status: Active
Philadelphia, Pennsylvania
Contact: Adam Craig Berger
Phone: 215-955-6084
Bryn Mawr Hospital
Status: Active
Bryn Mawr, Pennsylvania
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Cherry Tree Cancer Center
Status: Temporarily closed to accrual
Hanover, Pennsylvania
Contact: Amit B. Shah
Phone: 877-441-7957
Crozer-Chester Medical Center
Status: Temporarily closed to accrual
Upland, Pennsylvania
Contact: Rachelle M. Lanciano
Phone: 610-284-8237 Email: jolene.garney@crozer.org
Delaware County Memorial Hospital
Status: Temporarily closed to accrual
Drexel Hill, Pennsylvania
Contact: Rachelle M. Lanciano
Phone: 610-284-8237 Email: jolene.garney@crozer.org
Easton Hospital
Status: Active
Easton, Pennsylvania
Contact: Rajen P. Oza
Phone: 973-729-7001
Geisinger Medical Center
Status: Active
Danville, Pennsylvania
Contact: Thomas James Gergel
Phone: 570-271-5251
Geisinger Wyoming Valley / Henry Cancer Center
Status: Active
Wilkes-Barre, Pennsylvania
Contact: Thomas James Gergel
Phone: 570-271-5251
Guthrie Medical Group PC-Robert Packer Hospital
Status: Active
Sayre, Pennsylvania
Contact: Philip Andrew Lowry
Phone: 508-856-3216 Email: cancer.research@umassmed.edu
Lankenau Medical Center
Status: Active
Wynnewood, Pennsylvania
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Lehigh Valley Hospital-Cedar Crest
Status: Active
Allentown, Pennsylvania
Contact: Samir Narayan
Phone: 734-712-4673
Mercy Fitzgerald Hospital
Status: Temporarily closed to accrual
Darby, Pennsylvania
Contact: Adam Craig Berger
Phone: 215-955-6084
Northeast Radiation Oncology Center
Status: Active
Dunmore, Pennsylvania
Contact: Adam Craig Berger
Phone: 215-955-6084
Paoli Memorial Hospital
Status: Active
Paoli, Pennsylvania
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Reading Hospital
Status: Active
West Reading, Pennsylvania
Contact: Albert Yuen
Phone: 610-988-9323
Riddle Memorial Hospital
Status: Active
Media, Pennsylvania
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Thomas Jefferson University Hospital
Status: Active
Philadelphia, Pennsylvania
Contact: Adam Craig Berger
Phone: 215-955-6084
WellSpan Health-York Hospital
Status: Temporarily closed to accrual
York, Pennsylvania
Contact: Amit B. Shah
Phone: 877-441-7957

Rhode Island

Rhode Island Hospital
Status: Active
Providence, Rhode Island
Contact: Howard Safran
Phone: 401-444-1488

South Carolina

AnMed Health Cancer Center
Status: Active
Anderson, South Carolina
Contact: John Eric Doster
Phone: 864-512-1000
Carolina Blood and Cancer Care Associates PA
Status: Temporarily closed to accrual
Rock Hill, South Carolina
Contact: Patricia C. Griffin
Phone: 800-486-5941
Carolina Blood and Cancer Care Associates PA-Lancaster
Status: Temporarily closed to accrual
Lancaster, South Carolina
Contact: Patricia C. Griffin
Phone: 800-486-5941
Gibbs Cancer Center-Pelham
Status: Active
Greer, South Carolina
Contact: Patricia C. Griffin
Phone: 800-486-5941
Greenville Health System Cancer Institute-Andrews
Status: Temporarily closed to accrual
Greenville, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Greenville Health System Cancer Institute-Eastside
Status: Active
Greenville, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Greenville Health System Cancer Institute-Faris
Status: Active
Greenville, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Greenville Health System Cancer Institute-Greer
Status: Active
Greer, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Greenville Health System Cancer Institute-Seneca
Status: Active
Seneca, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Greenville Health System Cancer Institute-Spartanburg
Status: Active
Spartanburg, South Carolina
Contact: David Lawrence Grisell
Phone: 864-241-6251
Medical University of South Carolina
Status: Active
Charleston, South Carolina
Contact: David T. Marshall
Phone: 843-792-9321
Spartanburg Medical Center
Status: Active
Spartanburg, South Carolina
Contact: Patricia C. Griffin
Phone: 800-486-5941

South Dakota

Avera Cancer Institute
Status: Temporarily closed to accrual
Sioux Falls, South Dakota
Contact: Amy K. Krie
Phone: 888-634-7268 Email: oncregulatory@avera.org
Rapid City Regional Hospital
Status: Temporarily closed to accrual
Rapid City, South Dakota
Contact: Michael J. Swartz
Phone: 605-716-3982 Email: research@rcrh.org

Tennessee

Vanderbilt University / Ingram Cancer Center
Status: Active
Nashville, Tennessee
Contact: Anuradha Bapsi Chakravarthy
Phone: 800-811-8480

Texas

Deke Slayton Cancer Center
Status: Active
Webster, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
M D Anderson Cancer Center
Status: Temporarily closed to accrual
Houston, Texas
Contact: Christopher Haydon Crane
Phone: 212-639-7202
Memorial Hermann Memorial City Medical Center
Status: Active
Houston, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Cancer Center-Sherman
Status: Active
Sherman, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology - Central Austin Cancer Center
Status: Active
Austin, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology - Round Rock Cancer Center
Status: Active
Round Rock, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology - South Austin Cancer Center
Status: Active
Austin, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology Bedford
Status: Active
Bedford, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology Cancer Center Sugar Land
Status: Active
Sugar Land, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology-Arlington South
Status: Temporarily closed to accrual
Arlington, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology-Austin Midtown
Status: Active
Austin, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology-Flower Mound
Status: Active
Flower Mound, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology-Longview Cancer Center
Status: Active
Longview, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Texas Oncology-Seton Williamson
Status: Active
Round Rock, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
The Don and Sybil Harrington Cancer Center
Status: Temporarily closed to accrual
Amarillo, Texas
Contact: Stewart Allen Sharp
Phone: 806-212-1985 Email: gcravey@harringtoncc.org
The Klabzuba Cancer Center
Status: Temporarily closed to accrual
Fort Worth, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Tyler Cancer Center
Status: Active
Tyler, Texas
Contact: Vivek S. Kavadi
Phone: 281-277-5200

Utah

American Fork Hospital / Huntsman Intermountain Cancer Center
Status: Active
American Fork, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Dixie Medical Center Regional Cancer Center
Status: Active
Saint George, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Huntsman Cancer Institute / University of Utah
Status: Temporarily closed to accrual
Salt Lake City, Utah
Contact: Shane Lloyd
Phone: 801-581-4477 Email: clinical.trials@hci.utah.edu
Intermountain Medical Center
Status: Active
Murray, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
LDS Hospital
Status: Temporarily closed to accrual
Salt Lake City, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Logan Regional Hospital
Status: Active
Logan, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
McKay-Dee Hospital Center
Status: Active
Ogden, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Sandra L Maxwell Cancer Center
Status: Temporarily closed to accrual
Cedar City, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Utah Cancer Specialists-Salt Lake City
Status: Active
Salt Lake City, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950
Utah Valley Regional Medical Center
Status: Active
Provo, Utah
Contact: R. Jeffrey Lee
Phone: 801-507-3950

Virginia

Sentara Cancer Institute at Sentara CarePlex Hospital
Status: Active
Hampton, Virginia
Contact: Scott S. Williams
Phone: 757-388-2406
Sentara Norfolk General Hospital
Status: Active
Norfolk, Virginia
Contact: Scott S. Williams
Phone: 757-388-2406
Sentara Virginia Beach General Hospital
Status: Active
Virginia Beach, Virginia
Contact: Scott S. Williams
Phone: 757-388-2406

Washington

Cancer Care Northwest-North Spokane
Status: Temporarily closed to accrual
Spokane, Washington
Contact: Vivek S. Kavadi
Phone: 281-277-5200
Capital Medical Center
Status: Temporarily closed to accrual
Olympia, Washington
Contact: John A. Keech
Phone: 253-403-2394
Compass Oncology Vancouver
Status: Temporarily closed to accrual
Vancouver, Washington
Contact: Matthew C. Solhjem
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Legacy Salmon Creek Hospital
Status: Temporarily closed to accrual
Vancouver, Washington
Contact: Andrew Y. Kee
Phone: 800-220-4937 Email: cancer@lhs.org
MultiCare Allenmore Hospital
Status: Temporarily closed to accrual
Tacoma, Washington
Contact: John A. Keech
Phone: 253-403-2394
MultiCare Auburn Medical Center
Status: Temporarily closed to accrual
Auburn, Washington
Contact: John A. Keech
Phone: 253-403-2394
MultiCare Good Samaritan Hospital
Status: Temporarily closed to accrual
Puyallup, Washington
Contact: John A. Keech
Phone: 253-403-2394
MultiCare Tacoma General Hospital
Status: Active
Tacoma, Washington
Contact: John A. Keech
Phone: 253-403-2394
Northwest Medical Specialties PLLC
Status: Active
Tacoma, Washington
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Northwest NCI Community Oncology Research Program
Status: Active
Tacoma, Washington
Contact: John A. Keech
Phone: 253-403-2394
Overlake Hospital Medical Center
Status: Temporarily closed to accrual
Bellevue, Washington
Contact: John A. Keech
Phone: 253-403-2394
PeaceHealth Saint John Medical Center
Status: Active
Longview, Washington
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
PeaceHealth Southwest Medical Center
Status: Active
Vancouver, Washington
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence - Saint Peter Hospital
Status: Temporarily closed to accrual
Olympia, Washington
Contact: John A. Keech
Phone: 253-403-2394
Providence Regional Cancer Partnership
Status: Temporarily closed to accrual
Everett, Washington
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Regional Cancer System-Centralia
Status: Temporarily closed to accrual
Centralia, Washington
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Providence Regional Cancer System-Lacey
Status: Temporarily closed to accrual
Lacey, Washington
Contact: Benjamin Buckner Bridges
Phone: 208-381-3376 Email: mcdonagd@slhs.org
Saint Clare Hospital
Status: Temporarily closed to accrual
Lakewood, Washington
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Saint Francis Hospital
Status: Temporarily closed to accrual
Federal Way, Washington
Contact: Mehmet Sitki Copur
Phone: 800-998-2119
Saint Joseph Medical Center
Status: Temporarily closed to accrual
Tacoma, Washington
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Gig Harbor
Status: Active
Gig Harbor, Washington
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Puyallup
Status: Active
Puyallup, Washington
Contact: John A. Keech
Phone: 253-403-2394
Tacoma / Valley Radiation Oncology Centers-Saint Joe's
Status: Active
Tacoma, Washington
Contact: John A. Keech
Phone: 253-403-2394

West Virginia

West Virginia University Charleston
Status: Active
Charleston, West Virginia
Contact: Steven James Jubelirer
Phone: 304-344-3457
West Virginia University Healthcare
Status: Active
Morgantown, West Virginia
Contact: Malcolm David Mattes
Phone: 304-293-7374 Email: cancertrialsinfo@hsc.wvu.edu
Wheeling Hospital / Schiffler Cancer Center
Status: Active
Wheeling, West Virginia
Contact: Jondavid Pollock
Phone: 304-243-6442

Wisconsin

Bay Area Medical Center
Status: Active
Marinette, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Bellin Memorial Hospital
Status: Temporarily closed to accrual
Green Bay, Wisconsin
Contact: Charlie C. Pan
Phone: 920-435-8326
Cancer Center of Western Wisconsin
Status: Active
New Richmond, Wisconsin
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@parknicollet.com
Froedtert and the Medical College of Wisconsin
Status: Temporarily closed to accrual
Milwaukee, Wisconsin
Contact: Beth A. Erickson
Phone: 414-805-4380
Green Bay Oncology - Oconto Falls
Status: Temporarily closed to accrual
Oconto Falls, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Green Bay Oncology - Sturgeon Bay
Status: Temporarily closed to accrual
Sturgeon Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Green Bay Oncology at Saint Vincent Hospital
Status: Temporarily closed to accrual
Green Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Green Bay Oncology Limited at Saint Mary's Hospital
Status: Temporarily closed to accrual
Green Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Gundersen Lutheran Medical Center
Status: Active
La Crosse, Wisconsin
Contact: Kurt Oettel
Phone: 608-775-2385 Email: cancerctr@gundersenhealth.org
Saint Mary's Hospital
Status: Temporarily closed to accrual
Rhinelander, Wisconsin
Contact: Arlene A. Gayle
Phone: 715-389-4457
Saint Michael's Hospital
Status: Temporarily closed to accrual
Stevens Point, Wisconsin
Contact: Arlene A. Gayle
Phone: 715-389-4457
Saint Vincent Hospital Cancer Center at Saint Mary's
Status: Active
Green Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Status: Active
Sturgeon Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889
Saint Vincent Hospital Cancer Center Green Bay
Status: Active
Green Bay, Wisconsin
Contact: Eva N. Christensen
Phone: 920-433-8889

Ontario

London Regional Cancer Program
Status: Temporarily closed to accrual
London, Ontario
Contact: Barbara J. Fisher
Phone: 519-685-8600
Ottawa Hospital and Cancer Center-General Campus
Status: Active
Ottawa, Ontario
Contact: Jason Rene Pantarotto
Phone: 613-761-4395 Email: info@ohri.ca

Quebec

CHUM - Hopital Notre-Dame
Status: Temporarily closed to accrual
Montreal, Quebec
Contact: Marie-Pierre Campeau
Phone: 514-890-8000extn23611 Email: sylvie.beaudoin.chum@ssss.gouv.qc.ca

Israel

Rabin Medical Center
Status: Temporarily closed to accrual
Petach Tikva
Contact: Salomon M. Stemmer
Phone: +03-9378116 X 8120
Tel Aviv Sourasky Medical Center
Status: Temporarily closed to accrual
Tel Aviv
Contact: Ravit Geva
Phone: 011-972-3-6974761 Email: mop@tasmc.health.gov.il

Trial Objectives and Outline

PRIMARY OBJECTIVES:

I. To determine whether the addition of erlotinib (erlotinib hydrochloride) to gemcitabine (gemcitabine hydrochloride) adjuvant chemotherapy shows a signal for improved survival as compared to gemcitabine alone following R0 or R1 resection of head of pancreas adenocarcinoma (including adenocarcinoma of the head, neck, and uncinate process). (Phase II-R)

II. To determine whether the use of concurrent fluoropyrimidine and radiotherapy following adjuvant gemcitabine based chemotherapy or non-gemcitabine based chemotherapy such as modified fluorouracil-leucovorin-irinotecan-oxaliplatin regimen (FOLFIRINOX) further enhances survival for such patients who are without evidence of progressive disease after 5 months of adjuvant chemotherapy. (Phase III)

SECONDARY OBJECTIVES:

I. To evaluate disease-free survival of adjuvant chemotherapy followed by radiotherapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after 5 months of adjuvant chemotherapy.

II. To evaluate disease-free survival of standard adjuvant gemcitabine chemotherapy with and without erlotinib for patients with resected head of pancreas adenocarcinoma.

III. To evaluate adverse events with and without erlotinib for patients with resected head of pancreas adenocarcinoma.

IV. To evaluate adverse events of adjuvant chemotherapy with or without radiation therapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after adjuvant chemotherapy.

V. To evaluate preoperative cross-sectional imaging of the primary head of pancreas adenocarcinoma in order to determine the frequency with which objective criteria of resectability are present.

VI. To determine if patients reporting low baseline fatigue, as measured by the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue, predicts survival and to explore correlations between baseline fatigue, as measured by Patient-Reported Outcomes Measurement Information System (PROMIS), and survival.

OUTLINE: Patients without disease progression after treatment in arm I or II are randomized to 1 of 2 additional treatment arms (arm III or IV).

ARM I: Patients receive either gemcitabine hydrochloride or allowable combination chemotherapy per standard of care for 5 months.

ARM II (closed to accrual 4/2/14): Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1, 8, and 15 and erlotinib hydrochloride orally (PO) once daily on days 1-28. Treatment repeats every 28 days for up to 5 courses in the absence of disease progression or unacceptable toxicity.

ARM III: Patients receive the same treatment as in arm I for 1 month.

ARM IV: Patients receive the same treatment as in arm I for 1 month. Beginning within 7-21 days after completion of chemotherapy, patients undergo radiotherapy (3-dimensional conformal radiotherapy or intensity-modulated radiotherapy) 5 days per week for 5.5 weeks (28 fractions). During radiotherapy, patients receive either capecitabine PO twice daily (BID) 5 days per week or fluorouracil IV continuously for 5.5 weeks or until radiotherapy is completed.

After completion of study treatment, patients are followed up periodically.

Trial Phase & Type

Trial Phase

Phase III

Trial Type

Treatment

Lead Organization

Lead Organization
NRG Oncology

Principal Investigator
Ross Allen Abrams

Trial IDs

Primary ID RTOG-0848
Secondary IDs NCI-2011-01987, CDR0000659092, RTOG 0848
Clinicaltrials.gov ID NCT01013649

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