Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed By the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed By Surgery

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Status: Active

Description

This randomized phase II-R / III trial studies gemcitabine hydrochloride with or without erlotinib hydrochloride followed by the same chemotherapy regimen with or without radiation therapy and capecitabine or fluorouracil in treating patients with pancreatic cancer that was removed by surgery. Drugs used in chemotherapy, such as gemcitabine hydrochloride, capecitabine, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Erlotinib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells. Giving chemotherapy together with or without erlotinib hydrochloride and / or radiation therapy after surgery may kill any tumor cells that remain after surgery. It is not yet known whether chemotherapy is more effective when given with or without erlotinib hydrochloride and / or radiation therapy in treating pancreatic cancer.

Eligibility Criteria

Inclusion Criteria

  • Histologic proof of primary head of pancreas invasive adenocarcinoma managed with a potentially curative resection (i.e., removal of all gross tumor) involving a classic pancreaticoduodenectomy (Whipple) or a pylorus preserving pancreaticoduodenectomy; patients with invasive adenocarcinoma that also contains a component of intraductal papillary mucinous neoplasm (IPMN) are eligible * The operating surgeon must document in the operative note that a complete gross excision of the primary tumor was achieved; the pathology report must include documentation of the margin status and the size of the tumor; the pathology report must also include the status of the three major margins—bile duct, pancreatic parenchyma, and retroperitoneal (uncinate)
  • For patients who have not started their chemotherapy prior to registration, the interval between definitive tumor-related surgery and 1st step registration must be between 21-70 days; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, the interval between definitive tumor-related surgery and day one of adjuvant chemotherapy must be between 21-77 days
  • Patients will be staged according to the 6th edition American Joint Committee on Cancer (AJCC) staging system with pathologic stage T1-3, N0-1, M-0 being eligible
  • Zubrod performance status 0 or 1
  • Complete history and physical examination including weight and Zubrod status within 31 days of study entry (or within 31 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Before starting therapy the patient should be able to maintain adequate oral nutrition of >= 1500 calories estimated caloric intake per day and be free of significant nausea and vomiting
  • Complete blood count (CBC)/differential obtained within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Absolute neutrophil count (ANC) >= 1,500/mm^3
  • Platelets >= 100,000/mm^3
  • Hemoglobin (Hgb) >= 8.0 g/dL (transfusion or other intervention to achieve Hgb >= 8.0 g/dl is acceptable)
  • Post resection serum cancer antigen (CA)19-9 =< 180 units/mL AND prior to any systemic treatment
  • Serum total bilirubin =< twice the institutional upper limit of normal (ULN) within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Creatinine levels =< twice the institutional upper limit of normal within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Serum glutamic oxaloacetic transaminase (SGOT) must be =< 2.5 x institutional ULN within 21 days of registration on study (or within 21 days prior to day 1 of chemotherapy post-surgery for those patients having started chemotherapy prior to first step registration)
  • Negative serum pregnancy test for women of childbearing potential within 14 days of study registration
  • Abdominal/pelvic computed tomography (CT) scan with contrast is preferred; abdominal CT alone is acceptable only if insurance restrictions are experienced; chest CT/x-ray (CT of chest preferred) within 31 days of registration on study (or within 31 days prior to day 1 of chemo post-surgery for those patients having started chemotherapy prior to first step registration); patients allergic to intravenous (IV) contrast can have magnetic resonance imaging (MRI) of the abdomen/pelvis instead
  • Signed study-specific informed consent
  • Consultation, agreement, and documentation in the patient’s chart by a radiation oncologist that patient is suitable to receive radiotherapy per this protocol
  • Women of childbearing potential and male participants must practice adequate contraception
  • Patients with active human immunodeficiency virus (HIV) infection are eligible if their cluster of differentiation (CD)4 count is > 499/cu mm and their viral load is < 50 copies/ml; use of highly active antiretroviral treatment (HAART) is allowed

Exclusion Criteria

  • Patients with non-adenocarcinomas, adenosquamous carcinomas, islet cell (neuroendocrine) tumors, cystadenomas, cystadenocarcinomas, carcinoid tumors, duodenal carcinomas, distal bile duct, and ampullary carcinomas; patients with tumors that are largely IPMN with a minimal or minor component of invasive carcinoma are not eligible; patients with acinar carcinomas are not eligible; patients with IPMN’s that contain some secondary (minor) foci of adenocarcinoma are also not eligible
  • Patients managed with a total pancreatectomy, a distal pancreatectomy, or central pancreatectomy
  • Patients entering on the study after pancreaticoduodenectomy, who have not already started chemotherapy must not have had prior systemic chemotherapy for pancreas cancer; note that prior chemotherapy for a different cancer is allowable; for patients entering on the study who have already received up to 3 months of adjuvant chemotherapy as per the treating institution, patients must not have received adjuvant chemotherapy with agents other than gemcitabine, nab-paclitaxel, oxaliplatin, fluoropyrimidine, or irinotecan for the current pancreatic cancer; prior chemotherapy for a different cancer is allowable
  • Prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields
  • Previous history of invasive malignancy (except non-melanoma skin cancer) unless the patient has been disease free for at least 2 years prior to study entry (or first day of chemotherapy for patients having started chemotherapy prior to first step registration); patients with a previous history of carcinoma in situ are eligible
  • Severe, active co-morbidity, defined as follows per time points indicated below (or per time points indicated below prior to the first day of chemotherapy for patients having started chemotherapy prior to first step registration): * Unstable angina and/or congestive heart failure requiring hospitalization within the last 6 months * Transmural myocardial infarction within the 3 months of study registration * Acute bacterial or fungal infection requiring intravenous antibiotics at the time of registration * Chronic obstructive pulmonary disease exacerbation or other respiratory illness requiring hospitalization or precluding study therapy at the time of registration
  • Pregnant or lactating women
  • Women of childbearing potential and men who are sexually active and not willing/able to use medically acceptable forms of contraception
  • If surgical margin status cannot be determined after consultation with the operating surgeon and the institutional pathologist, the patient will be ineligible

Locations & Contacts

Alabama

Mobile
Providence Hospital
Status: Temporarily closed to accrual
Contact: Thaddeus A. Beeker
Phone: 251-445-9870 Email: pfrancisco@usouthal.edu

Alaska

Anchorage
Alaska Breast Care and Surgery LLC
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Alaska Women's Cancer Care
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Katmai Oncology Group
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Providence Alaska Medical Center
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org

Arizona

Scottsdale
Mayo Clinic in Arizona
Status: Temporarily closed to accrual
Contact: Michael G. Haddock
Phone: 855-776-0015

California

Auburn
Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Burbank
Providence Saint Joseph Medical Center / Disney Family Cancer Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Burlingame
Mills-Peninsula Medical Center
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Carmichael
Mercy San Juan Medical Center
Status: Temporarily closed to accrual
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Castro Valley
East Bay Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Jon M. Greif
Phone: 888-823-5923 Email: ctsucontact@westat.com
Duarte
City of Hope Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Nayana L. Vora
Phone: 800-826-4673 Email: becomingapatient@coh.org
Dublin
Epic Care-Dublin
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Emeryville
Bay Area Breast Surgeons Inc
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Epic Care Partners in Cancer Care
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Fremont
Kaiser Permanente-Fremont
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Fresno
California Cancer Center - North Fresno
Status: Active
Contact: William R. Silveira
Phone: 559-447-4050
Fresno Cancer Center
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Saint Agnes Medical Center
Status: Temporarily closed to accrual
Contact: Jedidiah Mercer Monson
Phone: 559-450-7790 Email: medresearch@samc.com
Greenbrae
Marin General Hospital
Status: Active
Contact: Lloyd T. Miyawaki
Phone: 415-925-7325
La Jolla
UC San Diego Moores Cancer Center
Status: Temporarily closed to accrual
Contact: Loren K. Mell
Phone: 858-552-8585ext7015
Los Angeles
Cedars Sinai Medical Center
Status: Temporarily closed to accrual
Contact: Nicholas Naumann Nissen
Phone: 310-423-8965
Kaiser Permanente Los Angeles Medical Center
Status: Active
Contact: Michael Raymond Girvigian
Phone: 626-564-3455
Los Angeles County-USC Medical Center
Status: Active
Contact: Syma Iqbal
Phone: 323-865-0451
USC / Norris Comprehensive Cancer Center
Status: Active
Contact: Syma Iqbal
Phone: 323-865-0451
Martinez
Contra Costa Regional Medical Center
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Modesto
Kaiser Permanente-Modesto
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Memorial Medical Center
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Mountain View
El Camino Hospital
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 888-823-5923 Email: ctsucontact@westat.com
Oakland
Alta Bates Summit Medical Center - Summit Campus
Status: Active
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Bay Area Tumor Institute
Status: Active
Contact: James Henry Feusner
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Hematology and Oncology Associates-Oakland
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 888-823-5923 Email: ctsucontact@westat.com
Highland General Hospital
Status: Temporarily closed to accrual
Contact: Jon M. Greif
Phone: 888-823-5923 Email: ctsucontact@westat.com
Kaiser Permanente Oakland-Broadway
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-Oakland
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Orange
UC Irvine Health / Chao Family Comprehensive Cancer Center
Status: Active
Contact: Jason Adam Zell
Phone: 877-827-8839 Email: ucstudy@uci.edu
Palo Alto
Palo Alto Medical Foundation Health Care
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Pleasanton
Valley Medical Oncology Consultants
Status: Temporarily closed to accrual
Contact: James Henry Feusner
Phone: 888-823-5923 Email: ctsucontact@westat.com
Rancho Cordova
Kaiser Permanente-Rancho Cordova Cancer Center
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Redwood City
Kaiser Permanente-Redwood City
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Richmond
Kaiser Permanente-Richmond
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Rohnert Park
Rohnert Park Cancer Center
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Roseville
Kaiser Permanente-Roseville
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
The Permanente Medical Group-Roseville Radiation Oncology
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sacramento
Kaiser Permanente - Sacramento
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-South Sacramento
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Mercy General Hospital Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Christopher Uwe Jones
Phone: 916-537-5237
South Sacramento Cancer Center
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sutter Medical Center Sacramento
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Saint Helena
Saint Helena Hospital
Status: Active
Contact: David John Tate
Phone: 707-967-3698
San Diego
Sharp Memorial Hospital
Status: Active
Contact: Robert M. Barone
Phone: 858-939-5062 Email: cathy.wood@sharp.com
San Francisco
California Pacific Medical Center-Pacific Campus
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Kaiser Permanente-San Francisco
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
San Jose
Kaiser Permanente-Santa Teresa-San Jose
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
San Leandro
Kaiser Permanente San Leandro
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
San Pablo
Doctors Medical Center- JC Robinson Regional Cancer Center
Status: Temporarily closed to accrual
Contact: Jon M. Greif
Phone: 888-823-5923 Email: ctsucontact@westat.com
San Rafael
Kaiser Permanente-San Rafael
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Santa Rosa
Kaiser Permanente-Santa Rosa
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
South San Francisco
Kaiser Permanente Cancer Treatment Center
Status: Active
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Kaiser Permanente-South San Francisco
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Stockton
Kaiser Permanente-Stockton
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Vacaville
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Vallejo
Kaiser Permanente-Vallejo
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Sutter Solano Medical Center / Cancer Center
Status: Active
Contact: Christopher Uwe Jones
Phone: 916-537-5237
Walnut Creek
Kaiser Permanente-Walnut Creek
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455

Colorado

Aurora
Rocky Mountain Cancer Centers-Aurora
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
The Medical Center of Aurora
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
University of Colorado Hospital
Status: Active
Contact: Karyn Aalami Goodman
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Boulder
Boulder Community Hospital
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Boulder
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Colorado Springs
Memorial Hospital Central
Status: Active
Contact: Karyn Aalami Goodman
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Penrose-Saint Francis Healthcare
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Rocky Mountain Cancer Centers-Penrose
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Denver
Colorado Blood Cancer Institute
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Porter Adventist Hospital
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Presbyterian - Saint Lukes Medical Center - Health One
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Midtown
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Rose
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rose Medical Center
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
SCL Health Saint Joseph Hospital
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Durango
Mercy Medical Center
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Englewood
Comprehensive Cancer Care and Research Institute of Colorado LLC
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Swedish Medical Center
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Fort Collins
Poudre Valley Hospital
Status: Active
Contact: Karyn Aalami Goodman
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Golden
Mountain Blue Cancer Care Center
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Grand Junction
Saint Mary's Hospital and Regional Medical Center
Status: Temporarily closed to accrual
Contact: Eduardo R. Pajon
Phone: 888-336-8262
Greeley
North Colorado Medical Center
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Greenwood Village
Rocky Mountain Cancer Centers-Greenwood Village
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Lakewood
Rocky Mountain Cancer Centers-Lakewood
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Saint Anthony Hospital
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Littleton
Littleton Adventist Hospital
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Rocky Mountain Cancer Centers-Littleton
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Sky Ridge Medical Center
Status: Temporarily closed to accrual
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Longmont
Longmont United Hospital
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Longmont
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Loveland
McKee Medical Center
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Parker
Parker Adventist Hospital
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Rocky Mountain Cancer Centers-Parker
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Pueblo
Rocky Mountain Cancer Centers - Pueblo
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Saint Mary Corwin Medical Center
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Thornton
North Suburban Medical Center
Status: Temporarily closed to accrual
Contact: Eduardo R. Pajon
Phone: 888-336-8262
Rocky Mountain Cancer Centers-Thornton
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Wheat Ridge
SCL Health Lutheran Medical Center
Status: Active
Contact: Keren Sturtz
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org

Connecticut

Bridgeport
Saint Vincent's Medical Center
Status: Active
Contact: Christine Van Cott
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Hartford
Hartford Hospital
Status: Temporarily closed to accrual
Contact: Andrew L. Salner
Phone: 860-545-5363
Meriden
Midstate Medical Center
Status: Temporarily closed to accrual
Contact: Neal B. Goldberg
Phone: 860-224-5660
New Britain
The Hospital of Central Connecticut
Status: Temporarily closed to accrual
Contact: Neal B. Goldberg
Phone: 860-224-5660
Norwich
Eastern Connecticut Hematology and Oncology Associates
Status: Temporarily closed to accrual
Contact: Dennis E. Slater
Phone: 860-886-8362
William Backus Hospital
Status: Temporarily closed to accrual
Contact: Dennis E. Slater
Phone: 860-886-8362

Delaware

Lewes
Beebe Medical Center
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Newark
Christiana Care Health System-Christiana Hospital
Status: Active
Contact: Adam Raben
Phone: 302-733-6227
Delaware Clinical and Laboratory Physicians PA
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Helen F Graham Cancer Center
Status: Active
Contact: Adam Raben
Phone: 302-733-6227
Medical Oncology Hematology Consultants PA
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Regional Hematology and Oncology PA
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Rehoboth Beach
Beebe Health Campus
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Seaford
Nanticoke Memorial Hospital
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227
Wilmington
Christiana Care Health System-Wilmington Hospital
Status: Temporarily closed to accrual
Contact: Adam Raben
Phone: 302-733-6227

District of Columbia

Washington
MedStar Georgetown University Hospital
Status: Temporarily closed to accrual
Contact: Keith R. Unger
Phone: 202-444-2223
MedStar Washington Hospital Center
Status: Temporarily closed to accrual
Contact: Pamela D. Randolph-Jackson
Phone: 202-877-8839

Florida

Coral Gables
UM Sylvester Comprehensive Cancer Center at Coral Gables
Status: Active
Contact: Lorraine Portelance
Phone: 305-243-2647
Deerfield Beach
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Status: Active
Contact: Lorraine Portelance
Phone: 305-243-2647
Fort Lauderdale
Holy Cross Hospital
Status: Temporarily closed to accrual
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
Gainesville
University of Florida Health Science Center �� Gainesville
Status: Active
Contact: Thomas J. George
Phone: 352-273-8675 Email: trials@cancer.ufl.edu
Jacksonville
Mayo Clinic in Florida
Status: Temporarily closed to accrual
Contact: Michael G. Haddock
Phone: 855-776-0015
Jupiter
Jupiter Medical Center
Status: Temporarily closed to accrual
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
Miami
Jackson Memorial Hospital-Holtz Children's Hospital
Status: Active
Contact: Lorraine Portelance
Phone: 305-243-2647
University of Miami Miller School of Medicine-Sylvester Cancer Center
Status: Active
Contact: Lorraine Portelance
Phone: 305-243-2647
Miami Beach
Mount Sinai Medical Center
Status: Temporarily closed to accrual
Contact: Michael A. Schwartz
Phone: 305-674-2625 Email: info@msccop.com
Orlando
Florida Hospital Orlando
Status: Temporarily closed to accrual
Contact: Robert James Sollaccio
Phone: 412-339-5294 Email: Roster@nrgoncology.org
UF Cancer Center at Orlando Health
Status: Active
Contact: Daniel Joseph Buchholz
Phone: 321-841-7246 Email: CancerClinicalTrials@orlandohealth.com
Trinity
Florida Cancer Affiliates
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu

Georgia

Atlanta
Emory University / Winship Cancer Institute
Status: Active
Contact: Bassel F. El-Rayes
Phone: 404-489-9164
Emory University Hospital Midtown
Status: Active
Contact: Bassel F. El-Rayes
Phone: 404-489-9164
Grady Health System
Status: Temporarily closed to accrual
Contact: Jerome Carl Landry
Phone: 404-489-9164
Saint Joseph's Hospital of Atlanta
Status: Active
Contact: Bassel F. El-Rayes
Phone: 404-489-9164
Columbus
John B Amos Cancer Center
Status: Temporarily closed to accrual
Contact: Andrew W. Pippas
Phone: 706-660-6404
Gainesville
Northeast Georgia Medical Center-Gainesville
Status: Active
Contact: Frank Greer Lake
Phone: 770-219-8800 Email: cancerpatient.navigator@nghs.com
Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's / Candler
Status: Active
Contact: John A. Pablo
Phone: 912-819-5704
Memorial University Medical Center
Status: Active
Contact: Aaron Watson Pederson
Phone: 912-350-8568

Hawaii

Ewa Beach
The Cancer Center of Hawaii-Leeward
Status: Temporarily closed to accrual
Contact: Richard Y. Lee
Phone: 808-586-2979
Honolulu
Hawaii Cancer Care Inc-Liliha
Status: Active
Contact: Richard Y. Lee
Phone: 808-586-2979
Kaiser Permanente Moanalua Medical Center
Status: Temporarily closed to accrual
Contact: Louis Fehrenbacher
Phone: 626-564-3455
Queen's Medical Center
Status: Active
Contact: Richard Y. Lee
Phone: 808-586-2979
The Cancer Center of Hawaii-Liliha
Status: Active
Contact: Richard Y. Lee
Phone: 808-586-2979
University of Hawaii Cancer Center
Status: Active
Contact: Richard Y. Lee
Phone: 808-586-2979

Idaho

Boise
Saint Luke's Mountain States Tumor Institute
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Fruitland
Saint Luke's Mountain States Tumor Institute - Fruitland
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Lewiston
Saint Joseph Regional Medical Center
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Meridian
Saint Luke's Mountain States Tumor Institute - Meridian
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Nampa
Saint Luke's Mountain States Tumor Institute - Nampa
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Post Falls
Kootenai Cancer Center
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Twin Falls
Saint Luke's Mountain States Tumor Institute-Twin Falls
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org

Illinois

Alton
Saint Anthony's Health
Status: Temporarily closed to accrual
Contact: Bethany Graham Sleckman
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Arlington Heights
Northwest Community Hospital
Status: Active
Contact: Stephen Schaeffer Nigh
Phone: 847-618-4968
Aurora
Rush - Copley Medical Center
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Bloomington
Illinois CancerCare-Bloomington
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Saint Joseph Medical Center
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Canton
Illinois CancerCare-Canton
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Carthage
Illinois CancerCare-Carthage
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Chicago
Advocate Illinois Masonic Medical Center
Status: Temporarily closed to accrual
Contact: Deepti A. Singh
Phone: 773-834-7424
John H Stroger Jr Hospital of Cook County
Status: Active
Contact: Thomas E. Lad
Phone: 312-864-6000
Northwestern University
Status: Active
Contact: John Patrick Hayes
Phone: 312-695-1301 Email: cancer@northwestern.edu
Presence Resurrection Medical Center
Status: Temporarily closed to accrual
Contact: Christopher G. Rose
Phone: 773-792-5116
Rush University Medical Center
Status: Active
Contact: Ross Allen Abrams
Phone: 312-942-5498 Email: clinical_trials@rush.edu
University of Chicago Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Stanley Lawrence Liauw
Phone: 773-834-7424
University of Illinois
Status: Active
Contact: Neeta Kiran Venepalli
Phone: 312-355-3046
Danville
Carle on Vermilion
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Decatur
Decatur Memorial Hospital
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Effingham
Carle Physician Group-Effingham
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Elmhurst
Elmhurst Memorial Hospital
Status: Active
Contact: Alexander Hantel
Phone: 708-226-4357
Eureka
Illinois CancerCare-Eureka
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Galesburg
Illinois CancerCare-Galesburg
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Western Illinois Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Geneva
Northwestern Medicine Cancer Center Delnor
Status: Active
Contact: Christopher M. George
Phone: 630-315-1918 Email: Claudine.Gamster@CadenceHealth.org
Harvey
Ingalls Memorial Hospital
Status: Active
Contact: Sulochana D. Yalavarthi
Phone: 708-915-4673 Email: clinicaltrials@ingalls.org
Kankakee
Presence Saint Mary's Hospital
Status: Temporarily closed to accrual
Contact: Sylvia V. Velinova Falls
Phone: 888-823-5923 Email: ctsucontact@westat.com
Kewanee
Illinois CancerCare-Kewanee Clinic
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Macomb
Illinois CancerCare-Macomb
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Mattoon
Carle Physician Group-Mattoon / Charleston
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Maywood
Loyola University Medical Center
Status: Active
Contact: William Small
Phone: 708-202-8387
Mount Vernon
Good Samaritan Regional Health Center
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Naperville
Edward Hospital / Cancer Center
Status: Active
Contact: Alexander Hantel
Phone: 708-226-4357
Normal
Community Cancer Center Foundation
Status: Temporarily closed to accrual
Contact: Nguyet Anh Le-Lindqwister
Phone: 309-243-3605
Ottawa
Illinois CancerCare-Ottawa Clinic
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Radiation Oncology of Northern Illinois
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Pekin
Illinois CancerCare-Pekin
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Peoria
Illinois CancerCare-Peoria
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Methodist Medical Center of Illinois
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
OSF Saint Francis Medical Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Peru
Illinois CancerCare-Peru
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Valley Radiation Oncology
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Plainfield
Edward Hospital / Cancer Center?Plainfield
Status: Active
Contact: Alexander Hantel
Phone: 708-226-4357
Princeton
Illinois CancerCare-Princeton
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Rockford
OSF Saint Anthony Medical Center
Status: Temporarily closed to accrual
Contact: Richard Ernest Nora
Phone: 815-227-2633
Springfield
Memorial Medical Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Saint John's Hospital
Status: Active
Contact: Samuel P. Au
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Urbana
Carle Cancer Center
Status: Active
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
The Carle Foundation Hospital
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Warrenville
Northwestern Medicine Cancer Center Warrenville
Status: Active
Contact: Christopher M. George
Phone: 630-315-1918 Email: Claudine.Gamster@CadenceHealth.org
Yorkville
Rush-Copley Healthcare Center
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com

Indiana

Beech Grove
Franciscan Saint Francis Health-Beech Grove
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Elkhart
Elkhart Clinic
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Elkhart General Hospital
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Michiana Hematology Oncology PC-Elkhart
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Fort Wayne
Parkview Hospital Randallia
Status: Active
Contact: Brian K. Chang
Phone: 260-373-8888 Email: parkviewresearch@parkview.com
Radiation Oncology Associates PC
Status: Active
Contact: Brian K. Chang
Phone: 260-373-8888 Email: parkviewresearch@parkview.com
Goshen
Goshen Center for Cancer Care
Status: Active
Contact: James A. Wheeler
Phone: 574-364-2973 Email: cccois@goshenhealth.com
Indianapolis
Indiana University / Melvin and Bren Simon Cancer Center
Status: Active
Contact: Susannah (Yovino) Ellsworth
Phone: 317-962-5731
IU Health Methodist Hospital
Status: Active
Contact: Susannah (Yovino) Ellsworth
Phone: 317-962-5731
Kokomo
Community Howard Regional Health
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
La Porte
IU Health La Porte Hospital
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Michigan City
Woodland Cancer Care Center
Status: Temporarily closed to accrual
Contact: Kalika Prasad Sarma
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Mishawaka
Memorial Regional Cancer Center Day Road
Status: Active
Contact: David Alan Hornback
Phone: 800-284-7370
Michiana Hematology Oncology PC-Mishawaka
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Saint Joseph Regional Medical Center-Mishawaka
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Plymouth
Michiana Hematology Oncology PC-Plymouth
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370
Richmond
Reid Health
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
South Bend
Memorial Hospital of South Bend
Status: Active
Contact: David Alan Hornback
Phone: 800-284-7370
Michiana Hematology Oncology PC-South Bend
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 574-237-1328
Northern Indiana Cancer Research Consortium
Status: Active
Contact: Robin T. Zon
Phone: 574-234-5123
Westville
Michiana Hematology Oncology PC-Westville
Status: Temporarily closed to accrual
Contact: Robin T. Zon
Phone: 800-284-7370

Iowa

Ames
Mary Greeley Medical Center
Status: Temporarily closed to accrual
Contact: Joseph James Merchant
Phone: 515-239-2621
McFarland Clinic PC-William R Bliss Cancer Center
Status: Temporarily closed to accrual
Contact: Joseph James Merchant
Phone: 515-239-2621
Boone
McFarland Clinic PC-Boone
Status: Temporarily closed to accrual
Contact: Joseph James Merchant
Phone: 515-239-2621
Clive
Medical Oncology and Hematology Associates-West Des Moines
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Mercy Cancer Center-West Lakes
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Des Moines
Iowa Lutheran Hospital
Status: Temporarily closed to accrual
Contact: Robert J. Behrens
Phone: 515-239-2621
Iowa Methodist Medical Center
Status: Active
Contact: Robert J. Behrens
Phone: 515-239-2621
Medical Oncology and Hematology Associates-Des Moines
Status: Temporarily closed to accrual
Contact: Robert J. Behrens
Phone: 515-239-2621
Medical Oncology and Hematology Associates-Laurel
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Mercy Medical Center - Des Moines
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Jefferson
McFarland Clinic PC-Jefferson
Status: Temporarily closed to accrual
Contact: Joseph James Merchant
Phone: 515-239-2621
Marshalltown
McFarland Clinic PC-Marshalltown
Status: Temporarily closed to accrual
Contact: Joseph James Merchant
Phone: 515-239-2621
Sioux City
Mercy Medical Center-Sioux City
Status: Temporarily closed to accrual
Contact: Donald B. Wender
Phone: 712-252-0088
Saint Luke's Regional Medical Center
Status: Temporarily closed to accrual
Contact: Donald B. Wender
Phone: 712-252-0088
Siouxland Regional Cancer Center
Status: Active
Contact: Donald B. Wender
Phone: 712-252-0088
West Des Moines
Mercy Medical Center-West Lakes
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Methodist West Hospital
Status: Temporarily closed to accrual
Contact: Robert J. Behrens
Phone: 515-239-2621

Kansas

Chanute
Cancer Center of Kansas - Chanute
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Dodge City
Cancer Center of Kansas - Dodge City
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
El Dorado
Cancer Center of Kansas - El Dorado
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Fort Scott
Cancer Center of Kansas - Fort Scott
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Independence
Cancer Center of Kansas-Independence
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Kingman
Cancer Center of Kansas-Kingman
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Lawrence
Lawrence Memorial Hospital
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Liberal
Cancer Center of Kansas-Liberal
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Manhattan
Cancer Center of Kansas-Manhattan
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
McPherson
Cancer Center of Kansas - McPherson
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Newton
Cancer Center of Kansas - Newton
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Overland Park
Menorah Medical Center
Status: Temporarily closed to accrual
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Luke's South Hospital
Status: Temporarily closed to accrual
Contact: Ashiq Masood
Phone: 888-823-5923 Email: ctsucontact@westat.com
Parsons
Cancer Center of Kansas - Parsons
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Pratt
Cancer Center of Kansas - Pratt
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Salina
Cancer Center of Kansas - Salina
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Topeka
Cotton O'Neil Cancer Center / Stormont Vail Health
Status: Temporarily closed to accrual
Contact: David E. Einspahr
Phone: 888-823-5923 Email: ctsucontact@westat.com
Wellington
Cancer Center of Kansas - Wellington
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Wichita
Associates In Womens Health
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas - Wichita
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Cancer Center of Kansas-Wichita Medical Arts Tower
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Via Christi Regional Medical Center
Status: Active
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Wesley Medical Center
Status: Active
Contact: Shaker R. Dakhil
Phone: 316-268-5374
Winfield
Cancer Center of Kansas - Winfield
Status: Temporarily closed to accrual
Contact: Shaker R. Dakhil
Phone: 316-268-5374

Kentucky

Lexington
Baptist Health Lexington
Status: Active
Contact: Firas B. Badin
Phone: 859-260-6425
University of Kentucky / Markey Cancer Center
Status: Active
Contact: Mahesh Ravindra Kudrimoti
Phone: 859-257-3379

Louisiana

New Orleans
Ochsner Medical Center Jefferson
Status: Active
Contact: Roland B. Hawkins
Phone: 504-842-3708
Tulane University Health Sciences Center
Status: Active
Contact: William Russell Robinson
Phone: 504-988-6121
Shreveport
Louisiana State University Health Sciences Center Shreveport
Status: Temporarily closed to accrual
Contact: Gary Von Burton
Phone: 318-813-1412

Maryland

Baltimore
Saint Agnes Hospital
Status: Active
Contact: Richard S. Hudes
Phone: 410-368-2910
Sinai Hospital of Baltimore
Status: Active
Contact: Mayer Gorbaty
Phone: 410-601-6120 Email: pridgely@lifebridgehealth.org
University of Maryland / Greenebaum Cancer Center
Status: Active
Contact: William Frank Regine
Phone: 800-888-8823
Salisbury
Peninsula Regional Medical Center
Status: Temporarily closed to accrual
Contact: John Romeo Mansueti
Phone: 866-922-6237

Massachusetts

Boston
Boston Medical Center
Status: Active
Contact: Minh Tam Truong
Phone: 617-638-8265
Burlington
Lahey Hospital and Medical Center
Status: Active
Contact: Keith Ellis Stuart
Phone: 781-744-8027
Fall River
Saint Anne's Hospital
Status: Active
Contact: Raymond L. Dugal
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Pittsfield
Berkshire Hematology Oncology PC
Status: Temporarily closed to accrual
Contact: Harvey Zimbler
Phone: 413-496-8205 Email: ggero@bhs1.org
Springfield
Baystate Medical Center
Status: Active
Contact: Seth A. Kaufman
Phone: 413-794-3565 Email: tamara.wrenn@baystatehealth.org

Michigan

Adrian
Bixby Medical Center
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Hickman Cancer Center
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Ann Arbor
Saint Joseph Mercy Hospital
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
University of Michigan Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Mary U. Feng
Phone: 877-827-3222
Brownstown
Henry Ford Cancer Institute¿Downriver
Status: Active
Contact: Eleanor M. Walker
Phone: 313-916-1784
Clinton Township
Henry Ford Macomb Hospital-Clinton Township
Status: Active
Contact: Eleanor M. Walker
Phone: 313-916-1784
Commerce
Huron Valley-Sinai Hospital
Status: Temporarily closed to accrual
Contact: Michael Matthew Dominello
Phone: 313-576-9363
Detroit
Henry Ford Hospital
Status: Active
Contact: Eleanor M. Walker
Phone: 313-916-1784
Saint John Hospital and Medical Center
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
Wayne State University / Karmanos Cancer Institute
Status: Active
Contact: Michael Matthew Dominello
Phone: 313-576-9363
Escanaba
Green Bay Oncology - Escanaba
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Farmington Hills
Weisberg Cancer Treatment Center
Status: Active
Contact: Michael Matthew Dominello
Phone: 313-576-9363
Grand Rapids
Mercy Health Saint Mary's
Status: Active
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Spectrum Health at Butterworth Campus
Status: Active
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Iron Mountain
Green Bay Oncology - Iron Mountain
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889
Kalamazoo
Borgess Medical Center
Status: Temporarily closed to accrual
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Bronson Methodist Hospital
Status: Temporarily closed to accrual
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
West Michigan Cancer Center
Status: Active
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Livonia
Saint Mary Mercy Hospital
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
Monroe
Mercy Memorial Hospital
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo Clinic Cancer Centers-Monroe
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Muskegon
Mercy Health Mercy Campus
Status: Active
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Pontiac
Saint Joseph Mercy Oakland
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
Royal Oak
William Beaumont Hospital-Royal Oak
Status: Active
Contact: Laura M. Nadeau
Phone: 248-551-7695
Saint Joseph
Lakeland Hospital
Status: Temporarily closed to accrual
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Marie Yeager Cancer Center
Status: Temporarily closed to accrual
Contact: Kathleen J. Yost
Phone: 616-391-1230 Email: crcwm-regulatory@crcwm.org
Troy
William Beaumont Hospital - Troy
Status: Active
Contact: Laura M. Nadeau
Phone: 248-551-7695
Warren
Saint John Macomb-Oakland Hospital
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
West Bloomfield
Henry Ford West Bloomfield Hospital
Status: Active
Contact: Eleanor M. Walker
Phone: 313-916-1784

Minnesota

Burnsville
Fairview Ridges Hospital
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Coon Rapids
Mercy Hospital
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Edina
Fairview-Southdale Hospital
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Fridley
Unity Hospital
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Maplewood
Minnesota Oncology Hematology PA-Maplewood
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Saint John's Hospital - Healtheast
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Minneapolis
Abbott-Northwestern Hospital
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Hennepin County Medical Center
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Robbinsdale
North Memorial Medical Health Center
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Rochester
Mayo Clinic
Status: Active
Contact: Michael G. Haddock
Phone: 855-776-0015
Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Saint Paul
Regions Hospital
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
United Hospital
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Waconia
Ridgeview Medical Center
Status: Temporarily closed to accrual
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Willmar
Rice Memorial Hospital
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com

Mississippi

Jackson
University of Mississippi Medical Center
Status: Temporarily closed to accrual
Contact: James Tate Thigpen
Phone: 601-815-6700
Pascagoula
Singing River Hospital
Status: Temporarily closed to accrual
Contact: James E. Clarkson
Phone: 228-809-5292

Missouri

Bolivar
Central Care Cancer Center-Carrie J Babb Cancer Center
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Bonne Terre
Parkland Health Center-Bonne Terre
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Branson
CoxHealth Cancer Center
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Cape Girardeau
Saint Francis Medical Center
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Southeast Cancer Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Columbia
University of Missouri - Ellis Fischel
Status: Temporarily closed to accrual
Contact: Donald C. Doll
Phone: 573-882-7440
Creve Coeur
Siteman Cancer Center at West County Hospital
Status: Active
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Independence
Centerpoint Medical Center LLC
Status: Temporarily closed to accrual
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Jefferson City
Capital Region Medical Center-Goldschmidt Cancer Center
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Joplin
Freeman Health System
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Mercy Hospital-Joplin
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Kansas City
Heartland Hematology and Oncology Associates Incorporated
Status: Temporarily closed to accrual
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Research Medical Center
Status: Active
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Luke's Hospital of Kansas City
Status: Active
Contact: Ashiq Masood
Phone: 888-823-5923 Email: ctsucontact@westat.com
Lee's Summit
Saint Luke's East - Lee's Summit
Status: Temporarily closed to accrual
Contact: Ashiq Masood
Phone: 888-823-5923 Email: ctsucontact@westat.com
Liberty
Liberty Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Rolla
Delbert Day Cancer Institute at PCRMC
Status: Active
Contact: Jay W. Carlson
Phone: 888-221-4849
Saint John's Clinic-Rolla-Cancer and Hematology
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Saint Joseph
Heartland Regional Medical Center
Status: Temporarily closed to accrual
Contact: Rakesh Gaur
Phone: 913-948-5588 Email: aroland@kccop.org
Saint Louis
Center for Cancer Care and Research
Status: Temporarily closed to accrual
Contact: Alan P. Lyss
Phone: 309-243-3605
Mercy Hospital Saint Louis
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Missouri Baptist Medical Center
Status: Active
Contact: James Lloyd Wade
Phone: 309-243-3605
Saint Louis Cancer and Breast Institute-South City
Status: Temporarily closed to accrual
Contact: Jay W. Carlson
Phone: 888-221-4849
Saint Louis University Hospital
Status: Temporarily closed to accrual
Contact: Bruce James Walz
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Saint Louis-Cape Girardeau CCOP
Status: Temporarily closed to accrual
Contact: Bethany Graham Sleckman
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Siteman Cancer Center-South County
Status: Temporarily closed to accrual
Contact: Jeffrey Robert Olsen
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Washington University School of Medicine
Status: Active
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Saint Peters
Siteman Cancer Center at Saint Peters Hospital
Status: Active
Contact: Parag J. Parikh
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Springfield
CoxHealth South Hospital
Status: Active
Contact: Jay W. Carlson
Phone: 888-221-4849
Mercy Hospital Springfield
Status: Active
Contact: Jay W. Carlson
Phone: 888-221-4849
Sullivan
Missouri Baptist Sullivan Hospital
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605
Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Status: Temporarily closed to accrual
Contact: James Lloyd Wade
Phone: 309-243-3605

Montana

Billings
Billings Clinic Cancer Center
Status: Active
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Northern Rockies Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Saint Vincent Healthcare
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Bozeman
Bozeman Deaconess Hospital
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Butte
Saint James Community Hospital and Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Great Falls
Benefis Healthcare- Sletten Cancer Institute
Status: Active
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Berdeaux, Donald MD (UIA Investigator)
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Great Falls Clinic
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Helena
Saint Peter's Community Hospital
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Kalispell
Kalispell Regional Medical Center
Status: Active
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Missoula
Montana Cancer Specialists
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Saint Patrick Hospital - Community Hospital
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org

Nebraska

Grand Island
CHI Health Saint Francis
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Kearney
CHI Health Good Samaritan
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Lincoln
Nebraska Cancer Research Center
Status: Temporarily closed to accrual
Contact: Gamini S. Soori
Phone: 402-991-8070 Email: mwilwerding@mvcc.cc
Omaha
Alegent Health Bergan Mercy Medical Center
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Alegent Health Immanuel Medical Center
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Alegent Health Lakeside Hospital
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Creighton University Medical Center
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Nebraska Methodist Hospital
Status: Active
Contact: Tien-Shew William Huang
Phone: 402-354-5144
University of Nebraska Medical Center
Status: Active
Contact: Chi Lin
Phone: 402-559-6941 Email: unmcrsa@unmc.edu

Nevada

Henderson
21st Century Oncology - Henderson
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Cancer and Blood Specialists-Henderson
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada - Henderson
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Las Vegas Cancer Center-Henderson
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Las Vegas
21st Century Oncology
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
21st Century Oncology - Fort Apache
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
21st Century Oncology - Vegas Tenaya
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Cancer and Blood Specialists-Shadow
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Cancer and Blood Specialists-Tenaya
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Cancer Therapy and Integrative Medicine
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada - Central Valley
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada - Northwest
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
Comprehensive Cancer Centers of Nevada-Summerlin
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Las Vegas Cancer Center-Medical Center
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Nevada Cancer Research Foundation CCOP
Status: Active
Contact: John Allan Ellerton
Phone: 702-384-0013
Nevada Cancer Specialists-Fort Apache
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Radiation Oncology Centers of Nevada Central
Status: Active
Contact: John Allan Ellerton
Phone: 805-474-9143
Radiation Oncology Centers of Nevada Southeast
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Summerlin Hospital Medical Center
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
University Medical Center of Southern Nevada
Status: Temporarily closed to accrual
Contact: John Allan Ellerton
Phone: 805-474-9143
Reno
Renown Regional Medical Center
Status: Active
Contact: Michael Chandler Hardacre
Phone: 775-982-4400

New Hampshire

Manchester
Elliot Hospital
Status: Active
Contact: Brian Robert Knab
Phone: 603-663-1800

New Jersey

Basking Ridge
Memorial Sloan Kettering Basking Ridge
Status: Active
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Camden
Cooper Hospital University Medical Center
Status: Temporarily closed to accrual
Contact: Ashish Bharat Patel
Phone: 856-325-6757
Livingston
Saint Barnabas Medical Center
Status: Active
Contact: Delia Radovich
Phone: 973-322-2470
Middletown
Memorial Sloan Kettering Monmouth Monmouth
Status: Temporarily closed to accrual
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Mount Holly
Virtua Memorial
Status: Temporarily closed to accrual
Contact: Lemuel S. Ariaratnam
Phone: 609-914-6762
Newark
Newark Beth Israel Medical Center
Status: Active
Contact: Charles S. Cathcart
Phone: 973-926-7230
Rutgers New Jersey Medical School
Status: Temporarily closed to accrual
Contact: Sabin Bhagwan Motwani
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Paramus
The Valley Hospital-Luckow Pavilion
Status: Active
Contact: Thomas J. Rakowski
Phone: 201-634-5792 Email: cparish@valleyhealth.com
Ridgewood
Valley Hospital
Status: Active
Contact: Thomas J. Rakowski
Phone: 201-634-5792 Email: cparish@valleyhealth.com
Sparta
Sparta Cancer Treatment Center
Status: Active
Contact: Adam Craig Berger
Phone: 215-955-6084
Voorhees
MD Anderson Cancer Center at Cooper-Voorhees
Status: Temporarily closed to accrual
Contact: Ashish Bharat Patel
Phone: 856-325-6757
Virtua Voorhees
Status: Temporarily closed to accrual
Contact: Lemuel S. Ariaratnam
Phone: 609-914-6762
Westwood
Valley Health System-Hematology / Oncology
Status: Active
Contact: Thomas J. Rakowski
Phone: 201-634-5792 Email: cparish@valleyhealth.com

New York

Albany
New York Oncology Hematology PC - Albany
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Brooklyn
Maimonides Medical Center
Status: Active
Contact: Bernadine Donahue
Phone: 212-263-4434 Email: prmc.coordinator@nyumc.org
Canandiaqua
Sands Cancer Center
Status: Temporarily closed to accrual
Contact: Yuhchyau Chen
Phone: 585-341-8113
Commack
Memorial Sloan Kettering Commack
Status: Active
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Glens Falls
Glens Falls Hospital
Status: Active
Contact: John Patrick Stoutenburg
Phone: 518-926-6700
Middletown
Orange Regional Medical Center
Status: Temporarily closed to accrual
Contact: Jeffrey M. Stewart
Phone: 845-342-7609
Mineola
NYU Winthrop Hospital
Status: Temporarily closed to accrual
Contact: Alexander A. Hindenburg
Phone: 516-663-3115
New Hyde Park
Long Island Jewish Medical Center
Status: Temporarily closed to accrual
Contact: Beatrice F. Bloom
Phone: 516-734-8954 Email: vvincigu@northwell.edu
New York
Laura and Isaac Perlmutter Cancer Center at NYU Langone
Status: Active
Contact: Kevin Lee Du
Phone: 212-263-4434 Email: prmc.coordinator@nyumc.org
Memorial Sloan-Kettering Cancer Center
Status: Active
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Rochester
Highland Hospital
Status: Active
Contact: Yuhchyau Chen
Phone: 585-341-8113
University of Rochester
Status: Active
Contact: Yuhchyau Chen
Phone: 585-341-8113
University Radiation Oncology
Status: Temporarily closed to accrual
Contact: Yuhchyau Chen
Phone: 585-341-8113
Rockville Centre
Memorial Sloan Kettering Rockville Centre
Status: Active
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
Sleepy Hollow
Memorial Sloan Kettering Sleepy Hollow
Status: Temporarily closed to accrual
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202
West Harrison
Memorial Sloan Kettering Westchester
Status: Active
Contact: Abraham Jing-Ching Wu
Phone: 212-639-7202

North Carolina

Charlotte
Carolinas Medical Center / Levine Cancer Institute
Status: Temporarily closed to accrual
Contact: John Stuart Salmon
Phone: 704-355-2884
Novant Health Presbyterian Medical Center
Status: Temporarily closed to accrual
Contact: Nasfat Shehadeh
Phone: 704-384-5369
Concord
Carolinas HealthCare System NorthEast
Status: Temporarily closed to accrual
Contact: John Stuart Salmon
Phone: 704-355-2884
Greenville
East Carolina University
Status: Active
Contact: Pamela Ann Lepera
Phone: 252-744-2391
Hendersonville
Park Ridge Hospital Breast Health Center
Status: Temporarily closed to accrual
Contact: Raymond Thertulien
Phone: 828-213-4150
Kinston
Kinston Medical Specialists PA
Status: Active
Contact: Peter Robins Watson
Phone: 252-559-2200
Matthews
Matthews Radiation Oncology Center
Status: Active
Contact: Nasfat Shehadeh
Phone: 704-384-5369
Raleigh
Rex Cancer Center
Status: Active
Contact: Justin Ja-Li Wu
Phone: 919-784-7209
Rutherfordton
Rutherford Hospital
Status: Temporarily closed to accrual
Contact: Patricia C. Griffin
Phone: 800-486-5941

Ohio

Akron
Akron General Medical Center
Status: Active
Contact: Mitchel L. Fromm
Phone: 330-344-6348
Alliance
Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Desiree E. Doncals
Phone: 330-615-4132
Belpre
Strecker Cancer Center-Belpre
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Bowling Green
Toledo Clinic Cancer Centers-Bowling Green
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Chillicothe
Adena Regional Medical Center
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Cincinnati
Bethesda North Hospital
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Good Samaritan Hospital - Cincinnati
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
University of Cincinnati / Barrett Cancer Center
Status: Temporarily closed to accrual
Contact: Kevin Patrick Redmond
Phone: 513-558-4553 Email: uchealthnews@uc.edu
Cleveland
Cleveland Clinic Cancer Center / Fairview Hospital
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Cleveland Clinic Foundation
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
MetroHealth Medical Center
Status: Active
Contact: Bruce J. Averbook
Phone: 216-778-8526 Email: kbauchens@metrohealth.org
Columbus
Columbus Oncology and Hematology Associates Inc
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Doctors Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Grant Medical Center
Status: Active
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Mount Carmel Health Center West
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Ohio State University Comprehensive Cancer Center
Status: Active
Contact: Dayssy Alexandra Diaz Pardo
Phone: 800-293-5066 Email: Jamesline@osumc.edu
Riverside Methodist Hospital
Status: Active
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
The Mark H Zangmeister Center
Status: Active
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Dayton
Good Samaritan Hospital - Dayton
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Grandview Hospital
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Miami Valley Hospital
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Samaritan North Health Center
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Delaware
Delaware Health Center-Grady Cancer Center
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Delaware Radiation Oncology
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Grady Memorial Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Elyria
Mercy Cancer Center-Elyria
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Findlay
Blanchard Valley Hospital
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Franklin
Atrium Medical Center-Middletown Regional Hospital
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Independence
Cleveland Clinic Cancer Center Independence
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Kettering
Kettering Medical Center
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Lancaster
Fairfield Medical Center
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Lancaster Radiation Oncology
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Lima
Lima Memorial Hospital
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Marietta
Marietta Memorial Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Maumee
Toledo Clinic Cancer Centers-Maumee
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Mayfield Heights
Hillcrest Hospital Cancer Center
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Mount Vernon
Knox Community Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Newark
Licking Memorial Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Newark Radiation Oncology
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Oregon
Saint Charles Hospital
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo Clinic Cancer Centers-Oregon
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Portsmouth
Southern Ohio Medical Center
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Ravenna
Robinson Radiation Oncology
Status: Temporarily closed to accrual
Contact: Mitchel L. Fromm
Phone: 330-344-6348
Salem
Cancer Care Center, Incorporated
Status: Temporarily closed to accrual
Contact: Desiree E. Doncals
Phone: 330-615-4132
Sandusky
North Coast Cancer Care
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Springfield
Springfield Regional Medical Center
Status: Temporarily closed to accrual
Contact: John Philip Kuebler
Phone: 614-488-2745 Email: sheree@columbusccop.org
Strongsville
Cleveland Clinic Cancer Center Strongsville
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Sylvania
Flower Hospital
Status: Active
Contact: Abhijit B. Saste
Phone: 419-824-1842
Tiffin
Mercy Hospital of Tiffin
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo
Mercy Saint Anne Hospital
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Saint Vincent Mercy Medical Center
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo Clinic Cancer Centers-Toledo
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Toledo Community Hospital Oncology Program CCOP
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
University of Toledo
Status: Active
Contact: Krishna Reddy
Phone: 419-383-6583
Troy
Upper Valley Medical Center
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Wauseon
Fulton County Health Center
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
West Chester
University Pointe
Status: Temporarily closed to accrual
Contact: Kevin Patrick Redmond
Phone: 513-558-4553 Email: uchealthnews@uc.edu
Westerville
Saint Ann's Hospital
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org
Wooster
Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Desiree E. Doncals
Phone: 330-615-4132
Cleveland Clinic Wooster Family Health and Surgery Center
Status: Active
Contact: Andrew D. Vassil
Phone: 866-223-8100
Xenia
Greene Memorial Hospital
Status: Temporarily closed to accrual
Contact: Howard M. Gross
Phone: 937-775-1350 Email: som_dcop@wright.edu
Zanesville
Genesis Healthcare System Cancer Care Center
Status: Temporarily closed to accrual
Contact: Timothy David Moore
Phone: 614-488-2745 Email: sheree@columbusccop.org

Oklahoma

Oklahoma City
University of Oklahoma Health Sciences Center
Status: Active
Contact: Terence S. Herman
Phone: 405-271-8777 Email: ou-clinical-trials@ouhsc.edu
Tulsa
Natalie Warren Bryant Cancer Center at Saint Francis
Status: Temporarily closed to accrual
Contact: Charles E. Stewart
Phone: 888-823-5923 Email: ctsucontact@westat.com

Oregon

Clackamas
Clackamas Radiation Oncology Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Gresham
Legacy Mount Hood Medical Center
Status: Active
Contact: Andrew Y. Kee
Phone: 855-776-0015
Milwaukie
Providence Milwaukie Hospital
Status: Temporarily closed to accrual
Contact: Matthew C. Solhjem
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Newberg
Providence Newberg Medical Center
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Oregon City
Providence Willamette Falls Medical Center
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Portland
Legacy Good Samaritan Hospital and Medical Center
Status: Active
Contact: Andrew Y. Kee
Phone: 855-776-0015
Providence Portland Medical Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Providence Saint Vincent Medical Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
The Dalles
Mid-Columbia Medical Center / Celilo Cancer Center
Status: Temporarily closed to accrual
Contact: Keith J. Stelzer
Phone: 541-296-7585

Pennsylvania

Abington
Abington Memorial Hospital
Status: Active
Contact: Wayne H. Pinover
Phone: 215-481-2402
Allentown
Lehigh Valley Hospital-Cedar Crest
Status: Active
Contact: Samir Narayan
Phone: 208-367-7954
Bryn Mawr
Bryn Mawr Hospital
Status: Active
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Danville
Geisinger Medical Center
Status: Active
Contact: Thomas James Gergel
Phone: 570-271-5251
Darby
Mercy Fitzgerald Hospital
Status: Temporarily closed to accrual
Contact: Adam Craig Berger
Phone: 215-955-6084
Drexel Hill
Delaware County Memorial Hospital
Status: Temporarily closed to accrual
Contact: Rachelle M. Lanciano
Phone: 610-284-8237 Email: jolene.garney@crozer.org
Dunmore
Northeast Radiation Oncology Center
Status: Active
Contact: Adam Craig Berger
Phone: 215-955-6084
Easton
Easton Hospital
Status: Active
Contact: Rajen P. Oza
Phone: 973-729-7001
Gettysburg
Adams Cancer Center
Status: Temporarily closed to accrual
Contact: Amit B. Shah
Phone: 877-441-7957
Hanover
Cherry Tree Cancer Center
Status: Temporarily closed to accrual
Contact: Amit B. Shah
Phone: 877-441-7957
Media
Riddle Memorial Hospital
Status: Active
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Natrona Heights
Allegheny Valley Hospital
Status: Temporarily closed to accrual
Contact: Jane Molnar Raymond
Phone: 877-284-2000
Paoli
Paoli Memorial Hospital
Status: Active
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
Philadelphia
Aria Health-Torresdale Campus
Status: Active
Contact: Adam Craig Berger
Phone: 215-955-6084
Einstein Medical Center Philadelphia
Status: Temporarily closed to accrual
Contact: Kenneth Lee Zeitzer
Phone: 215-456-3880
Thomas Jefferson University Hospital
Status: Active
Contact: Adam Craig Berger
Phone: 215-955-6084
Sayre
Guthrie Medical Group PC-Robert Packer Hospital
Status: Active
Contact: Philip Andrew Lowry
Phone: 508-856-3216 Email: cancer.research@umassmed.edu
Upland
Crozer-Chester Medical Center
Status: Temporarily closed to accrual
Contact: Rachelle M. Lanciano
Phone: 610-284-8237 Email: jolene.garney@crozer.org
West Reading
Reading Hospital
Status: Active
Contact: Michael L. Haas
Phone: 610-988-9323
Wilkes-Barre
Geisinger Wyoming Valley / Henry Cancer Center
Status: Active
Contact: Thomas James Gergel
Phone: 570-271-5251
Wynnewood
Lankenau Medical Center
Status: Active
Contact: Albert S. DeNittis
Phone: 484-476-2649 Email: ewend@mlhs.org
York
WellSpan Health-York Hospital
Status: Temporarily closed to accrual
Contact: Amit B. Shah
Phone: 877-441-7957

Rhode Island

Providence
Miriam Hospital
Status: Temporarily closed to accrual
Contact: Howard Safran
Phone: 401-444-1488
Radiation Oncology Associates Incorporated
Status: Temporarily closed to accrual
Contact: Howard Safran
Phone: 401-444-1488
Rhode Island Hospital
Status: Active
Contact: Howard Safran
Phone: 401-444-1488

South Carolina

Anderson
AnMed Health Cancer Center
Status: Active
Contact: John Eric Doster
Phone: 864-512-1000
Charleston
Medical University of South Carolina
Status: Active
Contact: David T. Marshall
Phone: 843-792-9321
Easley
Greenville Health System Cancer Institute-Easley
Status: Temporarily closed to accrual
Contact: David Lawrence Grisell
Phone: 864-679-3966
Greenville
Greenville Health System Cancer Institute-Andrews
Status: Temporarily closed to accrual
Contact: David Lawrence Grisell
Phone: 864-679-3966
Greenville Health System Cancer Institute-Butternut
Status: Temporarily closed to accrual
Contact: David Lawrence Grisell
Phone: 864-679-3966
Greenville Health System Cancer Institute-Eastside
Status: Active
Contact: David Lawrence Grisell
Phone: 864-679-3966
Greenville Health System Cancer Institute-Faris
Status: Active
Contact: David Lawrence Grisell
Phone: 864-679-3966
Greenville Memorial Hospital
Status: Temporarily closed to accrual
Contact: David Lawrence Grisell
Phone: 864-679-3966
Saint Francis Hospital
Status: Temporarily closed to accrual
Contact: Patricia C. Griffin
Phone: 800-486-5941
Greer
Gibbs Cancer Center-Pelham
Status: Active
Contact: Patricia C. Griffin
Phone: 800-486-5941
Greenville Health System Cancer Institute-Greer
Status: Active
Contact: David Lawrence Grisell
Phone: 864-679-3966
Lancaster
Carolina Blood and Cancer Care Associates PA-Lancaster
Status: Temporarily closed to accrual
Contact: Patricia C. Griffin
Phone: 800-486-5941
Rock Hill
Carolina Blood and Cancer Care Associates PA
Status: Temporarily closed to accrual
Contact: Patricia C. Griffin
Phone: 800-486-5941
Seneca
Greenville Health System Cancer Institute-Seneca
Status: Active
Contact: David Lawrence Grisell
Phone: 864-679-3966
Spartanburg
Greenville Health System Cancer Institute-Spartanburg
Status: Active
Contact: David Lawrence Grisell
Phone: 864-679-3966
Spartanburg Medical Center
Status: Active
Contact: Patricia C. Griffin
Phone: 800-486-5941

South Dakota

Rapid City
Rapid City Regional Hospital
Status: Temporarily closed to accrual
Contact: Michael J. Swartz
Phone: 605-716-3982 Email: research@rcrh.org
Sioux Falls
Avera Cancer Institute
Status: Temporarily closed to accrual
Contact: Amy K. Krie
Phone: 888-634-7268 Email: oncregulatory@avera.org

Tennessee

Nashville
Vanderbilt University / Ingram Cancer Center
Status: Active
Contact: Anuradha Bapsi Chakravarthy
Phone: 800-811-8480

Texas

Amarillo
The Don and Sybil Harrington Cancer Center
Status: Temporarily closed to accrual
Contact: Stewart Allen Sharp
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Arlington
Texas Oncology-Arlington South
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Austin
Texas Oncology - Central Austin Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Texas Oncology - South Austin Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Texas Oncology-Austin Midtown
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Bedford
Texas Oncology Bedford
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Flower Mound
Texas Oncology-Flower Mound
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Fort Worth
The Klabzuba Cancer Center
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Galveston
University of Texas Medical Branch
Status: Temporarily closed to accrual
Contact: Todd Allen Swanson
Phone: 409-772-1950 Email: clinical.research@utmb.edu
Houston
M D Anderson Cancer Center
Status: Temporarily closed to accrual
Contact: Christopher Haydon Crane
Phone: 212-639-7202
Memorial Hermann Memorial City Medical Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
League City
UTMB Cancer Center at Victory Lakes
Status: Temporarily closed to accrual
Contact: Todd Allen Swanson
Phone: 409-772-1950 Email: clinical.research@utmb.edu
Lewisville
Texas Oncology - Lewisville
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Longview
Texas Oncology-Longview Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
McKinney
Texas Oncology-McKinney
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Round Rock
Texas Oncology - Round Rock Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Texas Oncology-Seton Williamson
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
San Antonio
Cancer Care Centers of South Texas- Northeast
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Sherman
Texas Cancer Center-Sherman
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Sugar Land
Texas Oncology Cancer Center Sugar Land
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Temple
Scott and White Memorial Hospital
Status: Temporarily closed to accrual
Contact: Lucas Wong
Phone: 254-724-5407
Tyler
Tyler Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Webster
Deke Slayton Cancer Center
Status: Active
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu

Utah

American Fork
American Fork Hospital / Huntsman Intermountain Cancer Center
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Cedar City
Sandra L Maxwell Cancer Center
Status: Temporarily closed to accrual
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Logan
Logan Regional Hospital
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Murray
Intermountain Medical Center
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Ogden
McKay-Dee Hospital Center
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Provo
Utah Valley Regional Medical Center
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Saint George
Dixie Medical Center Regional Cancer Center
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Salt Lake City
Huntsman Cancer Institute / University of Utah
Status: Temporarily closed to accrual
Contact: Shane Lloyd
Phone: 801-581-4477 Email: clinical.trials@hci.utah.edu
LDS Hospital
Status: Temporarily closed to accrual
Contact: R. Jeffrey Lee
Phone: 801-408-1347
Utah Cancer Specialists-Salt Lake City
Status: Active
Contact: R. Jeffrey Lee
Phone: 801-408-1347

Virginia

Fredericksburg
Fredericksburg Oncology Inc
Status: Temporarily closed to accrual
Contact: Rex B. Mowat
Phone: 517-265-0116
Hampton
Sentara Cancer Institute at Sentara CarePlex Hospital
Status: Active
Contact: Scott S. Williams
Phone: 757-388-2406
Norfolk
Sentara Norfolk General Hospital
Status: Active
Contact: Scott S. Williams
Phone: 757-388-2406
Virginia Beach
Sentara Virginia Beach General Hospital
Status: Active
Contact: Scott S. Williams
Phone: 757-388-2406

Washington

Auburn
MultiCare Auburn Medical Center
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Bellevue
Overlake Hospital Medical Center
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Centralia
Providence Regional Cancer System-Centralia
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Everett
Providence Regional Cancer Partnership
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Federal Way
Saint Francis Hospital
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Gig Harbor
Tacoma / Valley Radiation Oncology Centers-Gig Harbor
Status: Active
Contact: John A. Keech
Phone: 907-458-5380
Lacey
Providence Regional Cancer System-Lacey
Status: Temporarily closed to accrual
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Lakewood
Saint Clare Hospital
Status: Temporarily closed to accrual
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Longview
PeaceHealth Saint John Medical Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Olympia
Capital Medical Center
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Providence - Saint Peter Hospital
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Puyallup
MultiCare Good Samaritan Hospital
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Tacoma / Valley Radiation Oncology Centers-Puyallup
Status: Active
Contact: John A. Keech
Phone: 907-458-5380
Spokane
Cancer Care Northwest - Spokane South
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Cancer Care Northwest-North Spokane
Status: Temporarily closed to accrual
Contact: Vivek S. Kavadi
Phone: 913-945-7552 Email: ctnursenav@kumc.edu
Tacoma
MultiCare Allenmore Hospital
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
MultiCare Tacoma General Hospital
Status: Active
Contact: John A. Keech
Phone: 907-458-5380
Northwest Medical Specialties PLLC
Status: Active
Contact: Mehmet Sitki Copur
Phone: 501-622-2100
Northwest NCI Community Oncology Research Program
Status: Active
Contact: John A. Keech
Phone: 253-403-2394
Saint Joseph Medical Center
Status: Temporarily closed to accrual
Contact: John A. Keech
Phone: 907-458-5380
Tacoma / Valley Radiation Oncology Centers-Saint Joe's
Status: Active
Contact: John A. Keech
Phone: 907-458-5380
Vancouver
Compass Oncology Vancouver
Status: Temporarily closed to accrual
Contact: Matthew C. Solhjem
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Legacy Salmon Creek Hospital
Status: Active
Contact: Andrew Y. Kee
Phone: 855-776-0015
PeaceHealth Southwest Medical Center
Status: Active
Contact: Benjamin Buckner Bridges
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org

West Virginia

Charleston
West Virginia University Charleston
Status: Active
Contact: Steven James Jubelirer
Phone: 304-388-9944
Morgantown
West Virginia University Healthcare
Status: Active
Contact: Malcolm David Mattes
Phone: 304-293-7374 Email: cancertrialsinfo@hsc.wvu.edu
Wheeling
Wheeling Hospital / Schiffler Cancer Center
Status: Active
Contact: Jondavid Pollock
Phone: 304-243-6442

Wisconsin

Antigo
Langlade Hospital and Cancer Center
Status: Temporarily closed to accrual
Contact: Darryl Roderick Barton
Phone: 877-405-6866
Chippewa Falls
Marshfield Clinic-Chippewa Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Eau Claire
Marshfield Clinic Cancer Center at Sacred Heart
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Sacred Heart Hospital
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Green Bay
Bellin Memorial Hospital
Status: Active
Contact: Charlie C. Pan
Phone: 920-435-8326
Green Bay Oncology at Saint Vincent Hospital
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889
Green Bay Oncology Limited at Saint Mary's Hospital
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889
Saint Vincent Hospital Cancer Center at Saint Mary's
Status: Active
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Saint Vincent Hospital Cancer Center Green Bay
Status: Active
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
La Crosse
Gundersen Lutheran Medical Center
Status: Active
Contact: Kurt Oettel
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Marinette
Bay Area Medical Center
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Marshfield
Marshfield Clinic
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Marshfield Medical Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Milwaukee
Froedtert and the Medical College of Wisconsin
Status: Temporarily closed to accrual
Contact: Beth A. Erickson
Phone: 414-805-4380
Minocqua
Marshfield Clinic-Minocqua Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
New Richmond
Cancer Center of Western Wisconsin
Status: Active
Contact: Paul W. Sperduto
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Oconto Falls
Green Bay Oncology - Oconto Falls
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Rhinelander
Marshfield Clinic at James Beck Cancer Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Saint Mary's Hospital
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Rice Lake
Marshfield Clinic-Rice Lake Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Stevens Point
Marshfield Clinic Cancer Care at Saint Michael's Hospital
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Saint Michael's Hospital
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Sturgeon Bay
Green Bay Oncology - Sturgeon Bay
Status: Temporarily closed to accrual
Contact: Eva N. Christensen
Phone: 920-433-8889
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Status: Active
Contact: Eva N. Christensen
Phone: 920-433-8889 Email: Christy.Gilchrist@hshs.org
Wausau
Aspirus Regional Cancer Center
Status: Temporarily closed to accrual
Contact: Darryl Roderick Barton
Phone: 877-405-6866
Marshfield Clinic-Wausau Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Weston
Diagnostic and Treatment Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Marshfield Clinic - Weston Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673
Wisconsin Rapids
Marshfield Clinic - Wisconsin Rapids Center
Status: Temporarily closed to accrual
Contact: Arlene A. Gayle
Phone: 800-347-0673

Wyoming

Casper
Rocky Mountain Oncology
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Sheridan
Welch Cancer Center
Status: Temporarily closed to accrual
Contact: Benjamin T. Marchello
Phone: 406-969-6060 Email: mccinfo@mtcancer.org

Ontario

London
London Regional Cancer Program
Status: Temporarily closed to accrual
Contact: Barbara J. Fisher
Phone: 519-685-8600
Ottawa
Ottawa Hospital and Cancer Center-General Campus
Status: Active
Contact: Jason Rene Pantarotto
Phone: 613-761-4395
Ottawa Hospital-Civic Campus
Status: Temporarily closed to accrual
Contact: Jason Rene Pantarotto
Phone: 613-761-4395

Quebec

Montreal
CHUM - Hopital Notre-Dame
Status: Active
Contact: Marie-Pierre Campeau
Phone: 514-890-8000ext23611 Email: sylvie.beaudoin.chum@ssss.gouv.qc.ca

Belgium

Turnhout
AZ Turnhout-Campus Saint Elizabeth
Status: Temporarily closed to accrual
Contact: Jozef Frans Emma M. Janssens Email: info@azturnhout.be

Israel

Petach Tikva
Rabin Medical Center
Status: Temporarily closed to accrual
Contact: Salomon M. Stemmer
Phone: 412-339-5294 Email: Roster@nrgoncology.org
Tel Aviv
Tel Aviv Sourasky Medical Center
Status: Temporarily closed to accrual
Contact: Ravit Geva
Phone: 011-972-3-6974761 Email: mop@tasmc.health.gov.il
Tel Hashomer
Chaim Sheba Medical Center
Status: Temporarily closed to accrual
Contact: Einat Shacham-Shmueli
Phone: 972 3 530-5943

Trial Objectives and Outline

PRIMARY OBJECTIVES:

I. To determine whether the addition of erlotinib (erlotinib hydrochloride) to gemcitabine (gemcitabine hydrochloride) adjuvant chemotherapy shows a signal for improved survival as compared to gemcitabine alone following R0 or R1 resection of head of pancreas adenocarcinoma (including adenocarcinoma of the head, neck, and uncinate process). (Phase II-R)

II. To determine whether the use of concurrent fluoropyrimidine and radiotherapy following adjuvant gemcitabine based chemotherapy or non-gemcitabine based chemotherapy such as modified fluorouracil-leucovorin-irinotecan-oxaliplatin regimen (FOLFIRINOX) further enhances survival for such patients who are without evidence of progressive disease after 5 months of adjuvant chemotherapy. (Phase III)

SECONDARY OBJECTIVES:

I. To evaluate disease-free survival of adjuvant chemotherapy followed by radiotherapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after 5 months of adjuvant chemotherapy.

II. To evaluate disease-free survival of standard adjuvant gemcitabine chemotherapy with and without erlotinib for patients with resected head of pancreas adenocarcinoma.

III. To evaluate adverse events with and without erlotinib for patients with resected head of pancreas adenocarcinoma.

IV. To evaluate adverse events of adjuvant chemotherapy with or without radiation therapy and concurrent fluoropyrimidine for patients with resected head of pancreas adenocarcinoma who are disease free after adjuvant chemotherapy.

V. To evaluate preoperative cross-sectional imaging of the primary head of pancreas adenocarcinoma in order to determine the frequency with which objective criteria of resectability are present.

VI. To determine if patients reporting low baseline fatigue, as measured by the Functional Assessment of Chronic Illness Therapy (FACIT)-Fatigue, predicts survival and to explore correlations between baseline fatigue, as measured by Patient-Reported Outcomes Measurement Information System (PROMIS), and survival.

OUTLINE: Patients without disease progression after treatment in arm I or II are randomized to 1 of 2 additional treatment arms (arm III or IV).

ARM I: Patients receive either gemcitabine hydrochloride or allowable combination chemotherapy per standard of care for 5 months.

ARM II (closed to accrual 4/2/14): Patients receive gemcitabine hydrochloride intravenously (IV) over 30 minutes on days 1, 8, and 15 and erlotinib hydrochloride orally (PO) once daily on days 1-28. Treatment repeats every 28 days for up to 5 courses in the absence of disease progression or unacceptable toxicity.

ARM III: Patients receive the same treatment as in arm I for 1 month.

ARM IV: Patients receive the same treatment as in arm I for 1 month. Beginning within 7-21 days after completion of chemotherapy, patients undergo radiotherapy (3-dimensional conformal radiotherapy or intensity-modulated radiotherapy) 5 days per week for 5.5 weeks (28 fractions). During radiotherapy, patients receive either capecitabine PO twice daily (BID) 5 days per week or fluorouracil IV continuously for 5.5 weeks or until radiotherapy is completed.

After completion of study treatment, patients are followed up periodically.

Trial Phase & Type

Trial Phase

Phase III

Trial Type

Treatment

Lead Organization

Lead Organization
NRG Oncology

Principal Investigator
Ross Allen Abrams

Trial IDs

Primary ID RTOG-0848
Secondary IDs NCI-2011-01987, CDR0000659092, RTOG 0848
Clinicaltrials.gov ID NCT01013649