Afatinib Dimaleate with or without Cetuximab in Treating Patients with Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer

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Basic Trial Information

PhaseTypeStatusAgeTrial IDs
Phase III, Phase IIBiomarker/Laboratory analysis, TreatmentActiveNot specifiedS1403
NCI-2014-02405, BI 1200.124, NCT02438722

Trial Description

Summary

This randomized phase II/III trial studies how well afatinib dimaleate with cetuximab works and compares it with afatinib dimaleate alone in treating patients with newly diagnosed stage IV or recurrent (has come back), epidermal growth factor receptor (EGFR) mutation positive non-small cell lung cancer. Afatinib dimaleate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as cetuximab, may block tumor growth in different ways by targeting certain cells. It is not yet known whether afatinib dimaleate is more effective when given alone or with cetuximab in treating patients with non-small cell lung cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To evaluate if there is sufficient evidence to continue to the phase III component by comparing progression-free survival (PFS) between patients randomized to afatinib (afatinib dimaleate) in combination with cetuximab versus afatinib alone in the first-line treatment of patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC). (Phase II)

II. To determine the efficacy of the combination of afatinib and cetuximab compared to afatinib alone as measured by overall survival (OS) in the first-line treatment of patients with advanced EGFR-mutant NSCLC. (Phase III)

SECONDARY OBJECTIVES:

I. To evaluate the overall response rate (confirmed and unconfirmed, complete and partial responses) in the subset of patients with measurable disease treated with afatinib plus cetuximab compared to afatinib alone.

II. To assess the safety of each treatment arm when used in the first-line setting.

III. To compare time to treatment failure and time to treatment discontinuation between randomized to afatinib in combination with cetuximab versus afatinib alone.

TERTIARY OBJECTIVES:

I. To investigate the molecular mechanisms that confer benefit from afatinib and afatinib plus cetuximab by evaluating whether the presence of de novo EGFR T790M mutation or other molecular alterations in the pre-treatment tumor influence the clinical outcomes.

II. To quantitatively assess whether the ratio of sensitizing EGFR (EGFRs) mutation to EGFR T790M influences outcome and is altered during treatment.

III. To evaluate the frequency of known mechanisms of resistance to EGFR-directed therapies in the context of afatinib plus cetuximab and afatinib alone treatment.

IV. To identify potential novel predictors of benefit to afatinib plus cetuximab.

V. To identify potential new mechanisms of resistance to EGFR-directed therapies.

VI. To establish patient-derived xenografts (PDXs) from a subset of patients by re-biopsy at the time of progressive disease for drug testing and genomic analysis.

VII. To assess whether circulating tumor markers can be used as indicators of sensitivity and resistance to afatinib plus cetuximab and afatinib alone.

VIII. To determine whether the levels of EGFR protein by immunohistochemistry predict for benefit to afatinib plus cetuximab and afatinib alone.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive afatinib dimaleate orally (PO) once daily (QD) on days 1-28 and cetuximab intravenously (IV) over 2 hours on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive afatinib dimaleate as in Arm I. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up for 3 years.

Eligibility Criteria

Inclusion Criteria:

Patients must have histologically or cytologically confirmed stage IV (American Joint Committee on Cancer [AJCC] 7th Edition) or recurrent non-small cell lung cancer (NSCLC)

Patients must have documented presence of an EGFR exon 19 deletion or exon 21 (L858R) substitution mutation; T790M mutation or other molecular abnormality will be allowed as long as it accompanies one of the mutations listed above; EGFR testing must be performed using a Food and Drug Administration (FDA)-approved test or in a Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory.

Patients must have tissue available and must agree to submission of tissue and blood; one to two paraffin-embedded tissue blocks or 15-20 unstained slides are requested (a minimum of 12 slides is required); cytology (i.e. fine-needle aspirations, pleural effusion specimens) is acceptable if a cell block or sufficient unstained slides are available; tumor material must be reviewed by a local pathologist who must confirm that at least 100 viable tumor cells are present in the sample and sign the S1403 Pathology Review Form; patients must also be willing to submit blood samples for correlative research at baseline, during treatment and at progression

Patients enrolled at sites participating in the Repeat Biopsy Study must agree to submission of tissue obtained by a repeat biopsy performed at the time of disease progression

Patients must not have received any prior systemic anticancer therapy for advanced or metastatic disease including chemotherapy or EGFR tyrosine kinase inhibitor therapy (including gefitinib, erlotinib, afatinib, or any experimental EGFR tyrosine kinase inhibitors [TKI] agents); prior chemotherapy for non-metastatic disease (i.e. adjuvant therapy or concurrent chemo-radiotherapy) is allowed as long as > 12 months has passed since completion of therapy; adjuvant EGFR-directed therapy is not allowed; local therapy (i.e. palliative radiotherapy) is allowed as long as a period of 7 days has passed since the last dose was received and the patient has recovered from any associated toxicity at the time of registration

Patients may have measurable or non-measurable disease documented by computed tomography (CT) or magnetic resonance imaging (MRI) within 42 days prior to registration; the CT from a combined positron emission tomography (PET)/CT may be used only if it is of diagnostic quality; laboratory parameters are not acceptable as the only evidence of disease; in order to qualify as measurable, measurable disease must be outside previous radiation field; all disease must be assessed and documented on the Baseline Tumor Assessment Form (Response Evaluation Criteria in Solid Tumors [RECIST] 1.1)

Patients must have a CT or MRI scan of the brain to evaluate for central nervous system (CNS) disease within 42 days prior to registration; patient must not have symptomatic brain metastases or evidence of leptomeningeal carcinomatosis; patients with asymptomatic brain metastases are eligible if off of steroids for at least 7 days prior to registration without development of symptoms

Patients must not have any known clinically active interstitial lung disease

Absolute neutrophil count (ANC) >= 1,500/mcL

Platelets >= 75,000/mcL

Hemoglobin >= 9 g/dL

Total bilirubin =< 1.5 x institutional upper limit of normal (IULN)

Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x IULN (or =< 5 x IULN for patients with known liver metastases)

Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 60 mL/min

Patients must not have significant gastrointestinal disorders with diarrhea as a major symptom (e.g. Crohn’s disease, malabsorption, etc)

Patients must be able to swallow medication by oral route

Patients must not have a history of clinically relevant cardiovascular abnormalities such as uncontrolled hypertension, congestive heart failure New York Heart Association (NYHA) classification of 3, unstable angina or poorly controlled arrhythmia or myocardial infarction within 6 months prior to registration; if clinically indicated, echocardiogram or multigated acquisition (MUGA) must be performed and cardiac ejection fraction must be >= 50%

Patients must not have had major surgery within 28 days prior to registration or be scheduled for surgery during the projected course of protocol treatment; tumor biopsy is allowed

Patients must not have a known history of active hepatitis B infection (defined as presence of hepatitis B surface antigen [Hep B sAg] and/ or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) seropositive

Patients must not have any other concomitant serious illness or organ system dysfunction which in the opinion of the investigator would either compromise patient safety or interfere with the evaluation of the safety of the study drug

Patients must not be planning to receive any other investigational agents during the course of protocol treatment

Patients must not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to afatinib and/or cetuximab

Prestudy history and physical must be obtained with 28 days prior to registration

Patients must have Zubrod performance status of 0 - 2

No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for three years

Patients must not be pregnant or nursing; women/men of reproductive potential must have agreed to use an effective contraceptive method; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures

Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines

As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

SWOG

  • National Cancer Institute
Sarah B. Goldberg, Principal Investigator

Trial Sites

U.S.A.

Arkansas
Hot Springs

Mercy Cancer Center-Hot Springs

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Jonesboro

Fowler Family Center for Cancer Care

Carroll Dean Scroggin
Ph: 870-936-7000

Carroll Dean Scroggin
Principal Investigator

California
Anaheim

Kaiser Permanente-Anaheim

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Auburn

Sutter Auburn Faith Hospital

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Auburn

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Bakersfield

AIS Cancer Center at San Joaquin Community Hospital

David R. Gandara
Ph: 916-734-3089

David R. Gandara
Principal Investigator

Baldwin Park

Kaiser Permanente-Baldwin Park

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Bellflower

Kaiser Permanente-Bellflower

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Berkeley

Alta Bates Summit Medical Center-Herrick Campus

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Burlingame

Mills-Peninsula Medical Center

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Cameron Park

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Castro Valley

Eden Hospital Medical Center

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Davis

Sutter Davis Hospital

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Fontana

Kaiser Permanente Hospital

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Fremont

Palo Alto Medical Foundation-Fremont

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Harbor City

Kaiser Permanente - Harbor City

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Irvine

Kaiser Permanente-Irvine

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

La Jolla

UC San Diego Moores Cancer Center

Lyudmila Alexandrovna Bazhenova
Ph: 858-822-5354
Email: cancercto@ucsd.edu

Lyudmila Alexandrovna Bazhenova
Principal Investigator

Los Angeles

Kaiser Permanente Los Angeles Medical Center

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Kaiser Permanente-Cadillac

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Marysville

Fremont - Rideout Cancer Center

David R. Gandara
Ph: 916-734-3089

David R. Gandara
Principal Investigator

Merced

Mercy UC Davis Cancer Center

Parminder S. Sidhu
Ph: 916-734-3089

Parminder S. Sidhu
Principal Investigator

Modesto

Memorial Medical Center

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Mountain View

Palo Alto Medical Foundation-Camino Division

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Palo Alto Medical Foundation-Gynecologic Oncology

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Novato

Sutter Cancer Research Consortium

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Palo Alto

Palo Alto Medical Foundation Health Care

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Panorama City

Kaiser Permanente - Panorama City

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Rancho Mirage

Eisenhower Medical Center

Davood Vafai
Ph: 760-834-3798

Davood Vafai
Principal Investigator

Riverside

Kaiser Permanente-Riverside

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Roseville

Sutter Cancer Centers Radiation Oncology Services-Roseville

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Sutter Roseville Medical Center

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Sacramento

Sutter Medical Center Sacramento

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

University of California Davis Comprehensive Cancer Center

David R. Gandara
Ph: 916-734-3089

David R. Gandara
Principal Investigator

San Diego

Kaiser Permanente-San Diego Mission

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Kaiser Permanente-San Diego Zion

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

San Francisco

California Pacific Medical Center-Pacific Campus

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

San Marcos

Kaiser Permanente-San Marcos

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Santa Rosa

Sutter Pacific Medical Foundation

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Sunnyvale

Palo Alto Medical Foundation-Sunnyvale

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Truckee

Gene Upshaw Memorial Tahoe Forest Cancer Center

David R. Gandara
Ph: 916-734-3089

David R. Gandara
Principal Investigator

Vacaville

Northbay Cancer Center

Brian G. Vikstrom
Ph: 707-624-8007

Brian G. Vikstrom
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Vacaville

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Vallejo

Sutter Solano Medical Center/Cancer Center

Ari David Baron
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Ari David Baron
Principal Investigator

Woodland Hills

Kaiser Permanente

Han A. Koh
Ph: 626-564-3455

Han A. Koh
Principal Investigator

Colorado
Colorado Springs

Penrose-Saint Francis Healthcare

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Rocky Mountain Cancer Centers-Penrose

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Denver

Porter Adventist Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Durango

Mercy Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Southwest Oncology PC

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Golden

Mountain Blue Cancer Care Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Saint Anthony Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Littleton

Littleton Adventist Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Longmont

Longmont United Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Rocky Mountain Cancer Centers-Longmont

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Parker

Parker Adventist Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Rocky Mountain Cancer Centers-Parker

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Saint Mary Corwin Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Thornton

Rocky Mountain Cancer Centers-Thornton

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Connecticut
Derby

Smilow Cancer Hospital-Derby Care Center

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Fairfield

Smilow Cancer Hospital Care Center-Fairfield

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Guilford

Medical Oncology and Hematology Group PC-Guilford

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Hartford

Smilow Cancer Hospital Care Center at Saint Francis

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Middletown

Middlesex Hospital

Susanna Hong
Ph: 860-358-2058
Email: beth_slifer@midhosp.org

Susanna Hong
Principal Investigator

New Haven

Yale University

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

North Haven

Yale-New Haven Hospital North Haven Medical Center

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Orange

Smilow Cancer Hospital-Orange Care Center

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Torrington

Charlotte Hungerford Hospital Center for Cancer Care

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Trumbull

Smilow Cancer Hospital Care Center-Trumbull

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Waterbury

Smilow Cancer Hospital-Waterbury Care Center

Sarah B. Goldberg
Ph: 203-785-5702

Sarah B. Goldberg
Principal Investigator

Florida
Pensacola

Sacred Heart Hospital

Yazan Alsayed
Ph: 850-416-4611
Email: ttamayo@shhpens.org

Yazan Alsayed
Principal Investigator

Georgia
Macon

Medical Center of Central Georgia

Frederick M. Schnell
Ph: 478-633-1226

Frederick M. Schnell
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Howard A. Zaren
Ph: 912-819-5704

Howard A. Zaren
Principal Investigator

Low Country Cancer Care Associates PC

Harvey Charles Lebos
Ph: 912-350-8568

Harvey Charles Lebos
Principal Investigator

Memorial University Medical Center

Harvey Charles Lebos
Ph: 912-350-8568

Harvey Charles Lebos
Principal Investigator

Summit Cancer Care-Memorial

Harvey Charles Lebos
Ph: 912-350-8568

Harvey Charles Lebos
Principal Investigator

Valdosta

South Georgia Medical Center/Pearlman Cancer Center

Samuel N. Ofori
Ph: 229-259-4628
Email: maryann.heddon@sgmc.org

Samuel N. Ofori
Principal Investigator

Hawaii
Aiea

Hawaii Oncology Inc-Pali Momi

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Pali Momi Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Ewa Beach

The Cancer Center of Hawaii-Leeward

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Honolulu

Hawaii Cancer Care Inc-Liliha

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Hawaii Cancer Care Inc-POB II

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Hawaii Oncology Inc-Kuakini

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Hawaii Oncology Inc-POB I

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Island Urology

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Kapiolani Medical Center for Women and Children

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Kuakini Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Queen's Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Straub Clinic and Hospital

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

The Cancer Center of Hawaii-Liliha

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

University of Hawaii Cancer Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Lihue

Wilcox Memorial Hospital and Kauai Medical Clinic

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Caldwell

Saint Alphonsus Cancer Care Center-Caldwell

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Coeur D'Alene

Kootenai Medical Center

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Emmett

Walter Knox Memorial Hospital

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Meridian

Idaho Urologic Institute-Meridian

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Nampa

Saint Alphonsus Medical Center-Nampa

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Post Falls

Kootenai Cancer Center

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Sandpoint

Kootenai Cancer Clinic

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Illinois
Aurora

Rush - Copley Medical Center

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Bloomington

Illinois CancerCare-Bloomington

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Canton

Illinois CancerCare-Canton

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Carbondale

Memorial Hospital of Carbondale

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Carterville

SIH Cancer Institute

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Carthage

Illinois CancerCare-Carthage

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Centralia

Centralia Oncology Clinic

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Danville

Carle on Vermilion

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Effingham

Carle Physician Group-Effingham

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Crossroads Cancer Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Elmhurst

Elmhurst Memorial Hospital

Amaryllis Gil
Ph: 630-758-5460
Email: Jrohde@emhc.org

Amaryllis Gil
Principal Investigator

Eureka

Illinois CancerCare-Eureka

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Galesburg

Illinois CancerCare-Galesburg

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Western Illinois Cancer Treatment Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Kewanee

Illinois CancerCare-Kewanee Clinic

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Macomb

Illinois CancerCare-Macomb

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Mattoon

Carle Physician Group-Mattoon/Charleston

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Maywood

Loyola University Medical Center

Courtney K. Regan
Ph: 708-226-4357

Courtney K. Regan
Principal Investigator

Moline

Trinity Medical Center

David Martens Spector
Ph: 563-359-9876

David Martens Spector
Principal Investigator

Mount Vernon

Good Samaritan Regional Health Center

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Naperville

Edward Hospital/Cancer Center

Amaryllis Gil
Ph: 630-758-5460
Email: Jrohde@emhc.org

Amaryllis Gil
Principal Investigator

Ottawa

Illinois CancerCare-Ottawa Clinic

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Pekin

Illinois CancerCare-Pekin

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Methodist Medical Center of Illinois

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Peru

Illinois CancerCare-Peru

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Valley Radiation Oncology

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Plainfield

Edward Hospital/Cancer Center?Plainfield

Amaryllis Gil
Ph: 630-758-5460
Email: Jrohde@emhc.org

Amaryllis Gil
Principal Investigator

Princeton

Illinois CancerCare-Princeton

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Rockford

SwedishAmerican Regional Cancer Center/ACT

Harvey E. Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Harvey E. Einhorn
Principal Investigator

Springfield

Memorial Medical Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Southern Illinois University School of Medicine

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Springfield Clinic

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Swansea

Cancer Care Specialists of Illinois-Swansea

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Memorial and Saint Elizabeth's Health Care Services LLP

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Urbana

Carle Cancer Center

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

The Carle Foundation Hospital

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Yorkville

Rush-Copley Healthcare Center

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Indiana
Evansville

Deaconess Clinic Downtown

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Michigan City

Franciscan Saint Anthony Health-Michigan City

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Woodland Cancer Care Center

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Newburgh

Chancellor Center for Oncology

Yujie Zhao
Ph: 630-978-6212
Email: Cancer.Research@rushcopley.com

Yujie Zhao
Principal Investigator

Richmond

Reid Health

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Iowa
Ames

Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

McFarland Clinic PC-William R Bliss Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Clive

Medical Oncology and Hematology Associates-West Des Moines

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Mercy Cancer Center-West Lakes

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Council Bluffs

Alegent Health Mercy Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Creston

Greater Regional Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Des Moines

Medical Oncology and Hematology Associates-Laurel

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Mercy Medical Center - Des Moines

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Fort Dodge

McFarland Clinic PC-Trinity Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

West Des Moines

Mercy Medical Center-West Lakes

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Kansas
Chanute

Cancer Center of Kansas - Chanute

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Dodge City

Cancer Center of Kansas - Dodge City

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

El Dorado

Cancer Center of Kansas - El Dorado

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Garden City

Saint Catherine Hospital

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Great Bend

Heartland Cancer Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Hays

Hays Medical Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Kansas City

University of Kansas Cancer Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

University of Kansas Cancer Center-West

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Kingman

Cancer Center of Kansas-Kingman

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Liberal

Cancer Center of Kansas-Liberal

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Manhattan

Cancer Center of Kansas-Manhattan

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

McPherson

Cancer Center of Kansas - McPherson

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Newton

Cancer Center of Kansas - Newton

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Olathe

Olathe Medical Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Overland Park

University of Kansas Cancer Center-Overland Park

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Parsons

Cancer Center of Kansas - Parsons

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Pittsburg

Via Christi Hospital-Pittsburg

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Prairie Village

Kansas City NCI Community Oncology Research Program

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Rakesh Gaur
Principal Investigator

Pratt

Cancer Center of Kansas - Pratt

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Salina

Cancer Center of Kansas - Salina

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Salina Regional Health Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Topeka

Saint Francis Hospital and Medical Center - Topeka

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Wellington

Cancer Center of Kansas - Wellington

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Westwood

University of Kansas Hospital-Westwood Cancer Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Wichita

Associates In Womens Health

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas - Wichita

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas-Wichita Medical Arts Tower

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Winfield

Cancer Center of Kansas - Winfield

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Kentucky
Bardstown

Flaget Memorial Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Corbin

Commonwealth Cancer Center-Corbin

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Lexington

Saint Joseph Hospital East

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Saint Joseph Radiation Oncology Resource Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Louisville

Jewish Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Jewish Hospital Medical Center Northeast

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Saints Mary and Elizabeth Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Shepherdsville

Jewish Hospital Medical Center South

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Maine
Bangor

Eastern Maine Medical Center

Thomas H. Openshaw
Ph: 207-973-4274

Thomas H. Openshaw
Principal Investigator

Brewer

Lafayette Family Cancer Center-EMMC

Thomas H. Openshaw
Ph: 207-973-4274

Thomas H. Openshaw
Principal Investigator

Massachusetts
Burlington

Lahey Hospital and Medical Center

Krishna Soujanya Gunturu
Ph: 781-744-8027

Krishna Soujanya Gunturu
Principal Investigator

Winchester

Winchester Hospital

Krishna Soujanya Gunturu
Ph: 781-744-8027

Krishna Soujanya Gunturu
Principal Investigator

Michigan
Ann Arbor

Saint Joseph Mercy Hospital

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

University of Michigan Comprehensive Cancer Center

Gregory Peter Kalemkerian
Ph: 800-865-1125

Gregory Peter Kalemkerian
Principal Investigator

Battle Creek

Bronson Battle Creek

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Brighton

IHA Hematology Oncology Consultants-Brighton

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Joseph Mercy Brighton

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Canton

IHA Hematology Oncology Consultants-Canton

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Joseph Mercy Canton Health Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Caro

Caro Cancer Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Chelsea

IHA Hematology Oncology Consultants-Chelsea

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Joseph Mercy Chelsea

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Clarkston

Hematology Oncology Consultants-Clarkston

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Newland Medical Associates-Clarkston

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Dearborn

Beaumont Hospital-Dearborn

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Detroit

Saint John Hospital and Medical Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Wayne State University/Karmanos Cancer Institute

Antoinette J. Wozniak
Ph: 313-576-9363

Antoinette J. Wozniak
Principal Investigator

East China

Great Lakes Cancer Management Specialists-Doctors Park

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Farmington Hills

Weisberg Cancer Treatment Center

Antoinette J. Wozniak
Ph: 313-576-9363

Antoinette J. Wozniak
Principal Investigator

Flint

Genesee Cancer and Blood Disease Treatment Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Genesee Hematology Oncology PC

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Genesys Hurley Cancer Institute

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Hurley Medical Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Gorsse Pointe Woods

Lymphoma Clinic of Michigan

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Grand Rapids

Mercy Health Saint Mary's

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Spectrum Health at Butterworth Campus

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Grosse Pointe Woods

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Michigan Breast Specialists-Grosse Pointe Woods

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Jackson

Allegiance Health

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Kalamazoo

Borgess Medical Center

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Bronson Methodist Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

West Michigan Cancer Center

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Lansing

Sparrow Hospital

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Livonia

Hope Cancer Clinic

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Mary Mercy Hospital

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Macomb Township

Hematology Oncology Associates East PC

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Michigan Breast Specialists-Macomb Township

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Marquette

UP Health System Hematology Oncology Marquette

Sheetal Suman Acharya
Ph: 906-225-4600
Email: Dianna.Larson@mghs.org

Sheetal Suman Acharya
Principal Investigator

UP Health System Marquette

Sheetal Suman Acharya
Ph: 906-225-4600
Email: Dianna.Larson@mghs.org

Sheetal Suman Acharya
Principal Investigator

Monroe

Monroe Cancer Center

Jeffrey Henry Muler
Ph: 419-824-1842

Jeffrey Henry Muler
Principal Investigator

Muskegon

Mercy Health Mercy Campus

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Niles

Lakeland Community Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Pontiac

21st Century Oncology-Pontiac

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Hope Cancer Center

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Newland Medical Associates-Pontiac

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Joseph Mercy Oakland

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Reed City

Spectrum Health Reed City Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Rochester Hills

Great Lakes Cancer Management Specialists-Rochester Hills

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saginaw

Oncology Hematology Associates of Saginaw Valley PC

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Mary's of Michigan

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint Joseph

Lakeland Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Marie Yeager Cancer Center

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Sterling Heights

Bhadresh Nayak MD PC-Sterling Heights

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Traverse City

Munson Medical Center

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Warren

Great Lakes Cancer Management Specialists-Macomb Professional Building

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Macomb Hematology Oncology PC

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Michigan Breast Specialists-Warren

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Saint John Macomb-Oakland Hospital

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

West Branch

Saint Mary's Oncology/Hematology Associates of West Branch

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Wyoming

Metro Health Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Ypsilanti

Huron Gastroenterology PC

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

IHA Hematology Oncology Consultants-Ann Arbor

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Minnesota
Bemidji

Sanford Clinic North-Bemidgi

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Burnsville

Fairview Ridges Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Coon Rapids

Mercy Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Edina

Fairview-Southdale Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Fridley

Unity Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Maple Grove

Fairview Maple Grove Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Maplewood

Minnesota Oncology Hematology PA-Maplewood

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Saint John's Hospital - Healtheast

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Health Partners Inc

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Hennepin County Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

New Ulm

New Ulm Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Robbinsdale

North Memorial Medical Health Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Saint Paul

Regions Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

United Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Shakopee

Saint Francis Regional Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Stillwater

Lakeview Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Waconia

Ridgeview Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Willmar

Rice Memorial Hospital

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Woodbury

Minnesota Oncology Hematology PA-Woodbury

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Wyoming

Fairview Lakes Medical Center

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Mississippi
Oxford

Family Cancer Center-Oxford

Raymond Uyiosa Osarogiagbon
Ph: 870-936-7000

Raymond Uyiosa Osarogiagbon
Principal Investigator

Pascagoula

Singing River Hospital

James E. Clarkson
Ph: 228-809-5292

James E. Clarkson
Principal Investigator

Southhaven

Baptist Memorial Hospital-Desoto

Raymond Uyiosa Osarogiagbon
Ph: 870-936-7000

Raymond Uyiosa Osarogiagbon
Principal Investigator

Missouri
Bolivar

Central Care Cancer Center-Carrie J Babb Cancer Center

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Bonne Terre

Parkland Health Center-Bonne Terre

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Branson

CoxHealth Cancer Center

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Southeast Cancer Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Jefferson City

Capital Region Medical Center-Goldschmidt Cancer Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Joplin

Freeman Health System

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Mercy Hospital-Joplin

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Kansas City

Kansas City Veterans Affairs Medical Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

The University of Kansas Cancer Center-North

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

The University of Kansas Cancer Center-South

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Truman Medical Center

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Lee's Summit

The University of Kansas Cancer Center-Lee's Summit

Chao Hui Huang
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Chao Hui Huang
Principal Investigator

Rolla

Delbert Day Cancer Institute at PCRMC

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Saint John's Clinic-Rolla-Cancer and Hematology

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Saint Joseph

Heartland Regional Medical Center

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Saint Louis

Mercy Hospital Saint Louis

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Missouri Baptist Medical Center

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Saint Louis Cancer and Breast Institute-South City

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Springfield

CoxHealth South Hospital

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Mercy Hospital Springfield

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

Sullivan

Missouri Baptist Sullivan Hospital

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

James Lloyd Wade
Ph: 309-243-3605

James Lloyd Wade
Principal Investigator

Montana
Billings

Billings Clinic Cancer Center

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Saint Vincent Healthcare

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Bozeman

Bozeman Deaconess Hospital

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Helena

Saint Peter's Community Hospital

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Missoula

Community Medical Hospital

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Saint Patrick Hospital - Community Hospital

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Nebraska
Grand Island

CHI Health Saint Francis

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Kearney

CHI Health Good Samaritan

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Heartland Hematology and Oncology

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Lincoln

Nebraska Cancer Research Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Nebraska Hematology and Oncology

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Saint Elizabeth Regional Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Southeast Nebraska Cancer Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Norfolk

Faith Regional Medical Offices West

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

North Platte

Great Plains Regional Medical Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Omaha

Alegent Health Bergan Mercy Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Alegent Health Immanuel Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Alegent Health Lakeside Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Creighton University Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Hemotology and Oncology Consultants PC

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Oncology Hematology West

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Oncology Hematology West PC

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

Papillion

Midlands Community Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Scottsbluff

Regional West Medical Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Gamini S. Soori
Principal Investigator

New Hampshire
Lebanon

Dartmouth Hitchcock Medical Center

Alexander David Fuld
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alexander David Fuld
Principal Investigator

Manchester

Norris Cotton Cancer Center-Manchester

Alexander David Fuld
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alexander David Fuld
Principal Investigator

Nashua

Norris Cotton Cancer Center-Nashua

Alexander David Fuld
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alexander David Fuld
Principal Investigator

New Jersey
Newark

Newark Beth Israel Medical Center

Lori Schleicher
Ph: 973-926-7230

Lori Schleicher
Principal Investigator

Vineland

Inspira Medical Center Vineland

Omar Al Ustwani
Ph: 856-641-7933

Omar Al Ustwani
Principal Investigator

Woodbury

Inspira Medical Center Woodbury

Carl J. Minniti
Ph: 856-641-7933

Carl J. Minniti
Principal Investigator

New Mexico
Albuquerque

New Mexico Oncology Hematology Consultants

Ian Rabinowitz
Ph: 505-925-0366
Email: LByatt@nmcca.org

Ian Rabinowitz
Principal Investigator

University of New Mexico Cancer Center

Ian Rabinowitz
Ph: 505-925-0366
Email: LByatt@nmcca.org

Ian Rabinowitz
Principal Investigator

Las Cruces

Memorial Medical Center - Las Cruces

Ian Rabinowitz
Ph: 505-925-0366
Email: LByatt@nmcca.org

Ian Rabinowitz
Principal Investigator

Santa Fe

Christus Saint Vincent Regional Cancer Center

Ian Rabinowitz
Ph: 505-925-0366
Email: LByatt@nmcca.org

Ian Rabinowitz
Principal Investigator

New York
Rochester

University of Rochester

Paul Michael Barr
Ph: 585-275-5830

Paul Michael Barr
Principal Investigator

Utica

Faxton-Saint Luke's Healthcare

Atul V. Butala
Ph: 888-823-5923
Email: ctsucontact@westat.com

Atul V. Butala
Principal Investigator

North Carolina
Asheville

Asheville Hematology-Oncology Associates

Raymond Thertulien
Ph: 828-213-4150

Raymond Thertulien
Principal Investigator

Cancer Care of Western North Carolina

Christopher H. Chay
Ph: 828-213-4150

Christopher H. Chay
Principal Investigator

Mission Hospital-Memorial Campus

Christopher H. Chay
Ph: 828-213-4150

Christopher H. Chay
Principal Investigator

Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

Goldsboro

Southeastern Medical Oncology Center-Goldsboro

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

Wayne Memorial Hospital

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

Hendersonville

Hendersonville Hematology and Oncology at Pardee

James Earl Radford
Ph: 828-696-4716

James Earl Radford
Principal Investigator

Margaret R Pardee Memorial Hospital

James Earl Radford
Ph: 828-696-1341

James Earl Radford
Principal Investigator

Park Ridge Hospital Breast Health Center

Raymond Thertulien
Ph: 828-213-4150

Raymond Thertulien
Principal Investigator

Jacksonville

Onslow Memorial Hospital

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

Kinston

Kinston Medical Specialists PA

Peter Robins Watson
Ph: 252-559-2200

Peter Robins Watson
Principal Investigator

Wilson

Southeastern Medical Oncology Center-Wilson

James N. Atkins
Ph: 252-399-7491

James N. Atkins
Principal Investigator

North Dakota
Bismarck

Sanford Bismarck Medical Center

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Fargo

Roger Maris Cancer Center

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Sanford Broadway Medical Center

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Grand Forks

Altru Cancer Center

Grant Richard Seeger
Ph: 855-776-0015

Grant Richard Seeger
Principal Investigator

Minot

Trinity Cancer Care Center

Stephen N.C. Makoni
Ph: 800-862-0005

Stephen N.C. Makoni
Principal Investigator

Ohio
Akron

Akron General Medical Center

Esther Hoogland Rehmus
Ph: 330-344-6348

Esther Hoogland Rehmus
Principal Investigator

Belpre

Strecker Cancer Center-Belpre

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Canton

Mercy Medical Center

Mitchell Haut
Ph: 888-293-4673

Mitchell Haut
Principal Investigator

Centerville

Dayton Physicians LLC-Miami Valley South

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Miami Valley Hospital South

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Chillicothe

Adena Regional Medical Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Cincinnati

Bethesda North Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Good Samaritan Hospital - Cincinnati

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Oncology Hematology Care Inc-Kenwood

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

TriHealth Cancer Institute-Anderson

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

TriHealth Cancer Institute-Westside

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Columbus

Columbus Oncology and Hematology Associates Inc

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Doctors Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Grant Medical Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Mount Carmel Health Center West

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Riverside Methodist Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

The Mark H Zangmeister Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Dayton

Dayton Physicians LLC-Samaritan North

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Good Samaritan Hospital - Dayton

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Miami Valley Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Samaritan North Health Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Delaware

Delaware Health Center-Grady Cancer Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Delaware Radiation Oncology

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Grady Memorial Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Findlay

Armes Family Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Blanchard Valley Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Orion Cancer Care

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Franklin

Atrium Medical Center-Middletown Regional Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Dayton Physicians LLC-Atrium

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Greenville

Dayton Physicians LLC-Wayne

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Wayne Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Kettering

First Dayton Cancer Care

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Greater Dayton Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Kettering Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Lancaster

Fairfield Medical Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Marietta

Marietta Memorial Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Middletown

Dayton Physicians LLC-Signal Point

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Mount Vernon

Knox Community Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Newark

Licking Memorial Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Newark Radiation Oncology

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Portsmouth

Southern Ohio Medical Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Sidney

Dayton Physicians LLC-Wilson

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Springfield

Springfield Regional Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Springfield Regional Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Sylvania

Flower Hospital

Jeffrey Henry Muler
Ph: 419-824-1842

Jeffrey Henry Muler
Principal Investigator

Toledo

The Toledo Hospital/Toledo Children's Hospital

Jeffrey Henry Muler
Ph: 419-824-1842

Jeffrey Henry Muler
Principal Investigator

Troy

Dayton Physicians LLC-Upper Valley

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Upper Valley Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Westerville

Saint Ann's Hospital

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Zanesville

Genesis Healthcare System Cancer Care Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Oklahoma
Oklahoma City

Mercy Hospital Oklahoma City

Jay W. Carlson
Ph: 888-221-4849

Jay W. Carlson
Principal Investigator

University of Oklahoma Health Sciences Center

Raid Aljumaily
Ph: 405-271-8777
Email: ou-clinical-trials@ouhsc.edu

Raid Aljumaily
Principal Investigator

Oregon
Baker City

Saint Alphonsus Medical Center-Baker City

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Grants Pass

Three Rivers Community Hospital

Charles Robert Dibb
Ph: 541-789-6176

Charles Robert Dibb
Principal Investigator

Medford

Providence Medford Medical Center

Charles Robert Dibb
Ph: 541-789-6176

Charles Robert Dibb
Principal Investigator

Rogue Valley Medical Center

Charles Robert Dibb
Ph: 541-789-6176

Charles Robert Dibb
Principal Investigator

Ontario

Saint Alphonsus Medical Center-Ontario

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Portland

Kaiser Permanente Northwest

Abdul Hai Mansoor
Ph: 503-335-2400

Abdul Hai Mansoor
Principal Investigator

Pennsylvania
Allentown

Lehigh Valley Hospital-Cedar Crest

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Bethlehem

Lehigh Valley Hospital - Muhlenberg

Philip J. Stella
Ph: 208-367-7954

Philip J. Stella
Principal Investigator

Ephrata

Ephrata Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Ephrata Community Hospital

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Gettysburg

Adams Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Hanover

Cherry Tree Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Lebanon

Sechler Family Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Reading

Penn State Health Saint Joseph Medical Center

Marc A. Rovito
Ph: 610-378-2336
Email: danielward2@catholichealth.net

Marc A. Rovito
Principal Investigator

West Chester

Chester County Hospital

William Emil Luginbuhl
Ph: 610-431-5297

William Emil Luginbuhl
Principal Investigator

Williamsport

Susquehanna Cancer Center

Warren Lewis Robinson
Ph: 800-598-4282

Warren Lewis Robinson
Principal Investigator

York

WellSpan Health-York Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

WellSpan Health-York Hospital

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

South Carolina
Easley

Greenville Health System Cancer Institute-Easley

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Florence

McLeod Regional Medical Center

Rajesh Bajaj
Ph: 843-679-7256

Rajesh Bajaj
Principal Investigator

Greenville

Greenville Health System Cancer Institute-Butternut

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Greenville Health System Cancer Institute-Eastside

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Greenville Health System Cancer Institute-Faris

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Greenville Memorial Hospital

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Saint Francis Cancer Center

Robert D. Siegel
Ph: 864-255-1713

Robert D. Siegel
Principal Investigator

Saint Francis Hospital

Robert D. Siegel
Ph: 864-255-1713

Robert D. Siegel
Principal Investigator

Greer

Greenville Health System Cancer Institute-Greer

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Seneca

Greenville Health System Cancer Institute-Seneca

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

Spartanburg

Greenville Health System Cancer Institute-Spartanburg

Jeffrey Kent Giguere
Ph: 864-679-3966

Jeffrey Kent Giguere
Principal Investigator

South Dakota
Sioux Falls

Sanford Cancer Center-Oncology Clinic

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Sanford USD Medical Center - Sioux Falls

Preston D. Steen
Ph: 712-252-0088

Preston D. Steen
Principal Investigator

Tennessee
Chattanooga

Memorial Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Franklin

Vanderbilt-Ingram Cancer Center Cool Springs

Leora Horn
Ph: 800-811-8480

Leora Horn
Principal Investigator

Hixson

Pulmonary Medicine Center of Chattanooga-Hixson

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Memphis

Baptist Memorial Hospital and Cancer Center-Memphis

Raymond Uyiosa Osarogiagbon
Ph: 870-936-7000

Raymond Uyiosa Osarogiagbon
Principal Investigator

Baptist Memorial Hospital for Women

Raymond Uyiosa Osarogiagbon
Ph: 870-936-7000

Raymond Uyiosa Osarogiagbon
Principal Investigator

Nashville

Vanderbilt Breast Center at One Hundred Oaks

Leora Horn
Ph: 800-811-8480

Leora Horn
Principal Investigator

Vanderbilt University/Ingram Cancer Center

Leora Horn
Ph: 800-811-8480

Leora Horn
Principal Investigator

Ooltewah

Memorial GYN Plus

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Texas
Bryan

Saint Joseph Regional Cancer Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

San Antonio

University of Texas Health Science Center at San Antonio

Anand Bhasker Karnad
Ph: 518-489-3612
Email: gerryann.currier@usoncology.com

Anand Bhasker Karnad
Principal Investigator

Vermont
Saint Johnsbury

Norris Cotton Cancer Center-North

Alexander David Fuld
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alexander David Fuld
Principal Investigator

Washington
Bremerton

Harrison HealthPartners Hematology and Oncology-Bremerton

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Harrison Medical Center

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Burien

Highline Medical Center-Main Campus

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Enumclaw

Saint Elizabeth Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Federal Way

Saint Francis Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Lakewood

Saint Clare Hospital

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Poulsbo

Harrison HealthPartners Hematology and Oncology-Poulsbo

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Tacoma

Franciscan Research Center-Northwest Medical Plaza

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

Northwest Medical Specialties PLLC

Mehmet Sitki Copur
Ph: 501-622-2100

Mehmet Sitki Copur
Principal Investigator

West Virginia
Huntington

Saint Mary's Medical Center

Arvinder Singh Bir
Ph: 888-823-5923
Email: ctsucontact@westat.com

Arvinder Singh Bir
Principal Investigator

Wisconsin
Antigo

Langlade Hospital and Cancer Center

Harish G. Ahuja
Ph: 877-405-6866

Harish G. Ahuja
Principal Investigator

Burlington

Aurora Cancer Care-Southern Lakes VLCC

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Chippewa Falls

Marshfield Clinic-Chippewa Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Eau Claire

Marshfield Clinic Cancer Center at Sacred Heart

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Sacred Heart Hospital

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Fond Du Lac

Aurora Health Center-Fond du Lac

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Germantown

Aurora Health Care Germantown Health Center

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Grafton

Aurora Cancer Care-Grafton

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Kenosha

Aurora Cancer Care-Kenosha South

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Kurt Oettel
Ph: 920-433-8889
Email: Christy.Gilchrist@hshs.org

Kurt Oettel
Principal Investigator

Ladysmith

Marshfield Clinic - Ladysmith Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Marinette

Aurora Bay Area Medical Group-Marinette

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Vince Lombardi Cancer Clinic-Marinette

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Marshfield

Marshfield Clinic

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Saint Joseph's Hospital

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Mequon

Columbia Saint Mary's Hospital - Ozaukee

Ranveer Nand
Ph: 888-823-5923
Email: ctsucontact@westat.com

Ranveer Nand
Principal Investigator

Milwaukee

Aurora Cancer Care-Milwaukee

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Aurora Saint Luke's Medical Center

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Aurora Sinai Medical Center

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Columbia Saint Mary's Water Tower Medical Commons

Ranveer Nand
Ph: 888-823-5923
Email: ctsucontact@westat.com

Ranveer Nand
Principal Investigator

Minocqua

Marshfield Clinic-Minocqua Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

New Richmond

Cancer Center of Western Wisconsin

David Mark King
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

David Mark King
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Racine

Aurora Cancer Care-Racine

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Rice Lake

Lakeview Medical Center-Marshfield Clinic

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Marshfield Clinic-Rice Lake Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Sheboygan

Vince Lombardi Cancer Clinic-Sheboygan

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Stevens Point

Marshfield Clinic Stevens Point Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Summit

Aurora Medical Center in Summit

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Two Rivers

Vince Lombardi Cancer Clinic-Two Rivers

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Wausau

Aspirus Regional Cancer Center

Harish G. Ahuja
Ph: 877-405-6866

Harish G. Ahuja
Principal Investigator

Marshfield Clinic-Wausau Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Wauwatosa

Aurora Cancer Care-Milwaukee West

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

West Allis

Aurora West Allis Medical Center

Dhimant R. Patel
Ph: 715-735-6523

Dhimant R. Patel
Principal Investigator

Weston

Diagnostic and Treatment Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Marshfield Clinic - Weston Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Wisconsin Rapids

Aspirus UW Cancer Center

Harish G. Ahuja
Ph: 877-405-6866

Harish G. Ahuja
Principal Investigator

Marshfield Clinic - Wisconsin Rapids Center

Bilal H. Naqvi
Ph: 715-717-3956

Bilal H. Naqvi
Principal Investigator

Wyoming
Cody

Billings Clinic-Cody

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Sheridan

Welch Cancer Center

Benjamin T. Marchello
Ph: 406-969-6060
Email: mccinfo@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT02438722

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.