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CCG at AACR 2019

, by CCG Staff

The Center for Cancer Genomics will be at the 2019 American Association for Cancer Research (AACR) Annual Meeting to present some of our latest research programs and initiatives. Team members from the Office of Cancer Genomics (OCG) and Genomic Data Commons (GDC) will be available throughout the week to discuss our programs and take feedback.

Sunday, March 31

NCI’s Translational Research Programs: Development and Use of Next-Generation Cancer Models for Precision Oncology
5:30 - 6:30 PM | Room A406 - Georgia World CC | Audio Recording and Slides

An NCI-sponsored session providing an overview of the Human Cancer Models Initiative, which is developing "next-generation" cancer models including organoids and conditionally reprogrammed cells from many types of cancers.

  • Overview of the HCMI - Lauren Hurd, PhD (HCMI Program Manager)
  • Downstream Applications of Cancer Models by CTD2 Network - Subhashini Jagu, PhD, (CTD2 Program Manager)
  • Developing Next-Generation Cancer Models - Eva Tonsing-Carter, PhD (HCMI Program Manager)
  • HCMI Data at the NCI GDC - Sharon Gaheen (GDC Technical Project Manager, Leidos Biomedical Research, Inc.)

Monday, April 1

Clinical and Genomic Data Analysis, Visualization, and Exploration in the GDC
12:30 - 1:00 PM | NCI Booth #2111

A Meet the Experts Session on GDC Data Analysis, Visualization, and Exploration (DAVE) tools for exploring cancer genomic data. Exploring the most frequently mutated genes and common mutations across the GDC, developing custom cohorts, and performing survival analyses will be among topics covered. Also, an upcoming clinical data analysis feature for building synthetic cohorts and analyzing clinical outcomes. With Michael Fitzsimons, PhD (GDC Director of User Services and Outreach, University of Chicago).

Pediatric Genomic Data Inventory: A Valuable Resource of Pediatric Cancer Projects
4:00 - 4:30 PM | NCI Booth #2111

A Meet the Experts Session on finding and contributing pediatric cancer genomic data to the PGDI public resource. With Pamela Birriel, PhD (OCG Communications Manager).

Maintaining Quality Control, Consistency, and Privacy in the Development of HCMI Next-generation Cancer Models
4:30 – 5:00 PM | NCI Booth #2111

A Meet the Experts Session on essential aspects of developing a new resource of more accurate cancer models for the cancer research community. With Lauren Hurd, PhD (HCMI Program Manager).

Tuesday, April 2

NCI Office of Cancer Genomics: Promoting multidisciplinary research to translate findings into the clinic and advance precision oncology
1:00 - 5:00 PM | Poster Section 34

A presentation of the various initatives from OCG to advance the molecular understanding of cancers and precision medicine, including: Cancer Genome Characterization Initiative (CGCI), Therapeutically Applicable Research to Generate Effective Treatments (TARGET), Pediatric Genomic Data Inventory (PGDI), Cancer Target Discovery and Development (CTD2) Network and Human Cancer Models Initiative (HCMI). With Cindy Kyi, PhD (OCG Health Communications Fellow).

HCMI: Next-generation Cancer Models Are an Ongoing Community Resource
3:00 - 3:30 PM  | NCI Booth #2111

A Meet the Experts Session providing an overview of HCMI, a commmunity resource of next-generation, tumor-derived culture models annotated with genomic and clinical data. With Eva Tonsing-Carter, PhD (HCMI Program Manager). 

Raw Genomic Data Processing: A Look at GDC’s Bioinformatics Pipelines
4:00 - 4:30 PM | NCI Booth #2111

A Meet the Experts Session on how the GDC processes raw, genomic data into higher-level data, such as somatic mutation calls and copy number estimates. A walk-through of some of GDC’s bioinformatics pipelines, including sequence alignment and application of various mutation and copy number callers. With Michael Fitzsimons, PhD (GDC Director of User Services and Outreach, University of Chicago).

Information Kiosks at NCI Exhibit Booth #2111

Team members will be available all week to answer questions on CCG programs and take feedback:

Data Sharing Kiosk with the Genomic Data Commons and the Center for Biomedical Informatics & Information Technology

Genomics and Strategic Initiatives Kiosk with the Office of Cancer Genomics and the Center for Strategic Science Initiatives

Other NCI sessions and activities at AACR 2019

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