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NCI Bottom Line: A Blog about Grants and More

This grantee-focused blog covers the latest on NCI’s fiscal landscape, funding decisions, grants policy news, processes, and more.

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  • A group of multicolored arrows move diagonally towards the top-right of the image; in the top left is the NIH luggage tag with text reading "The Common Fund" below it.
    • By Dr. Norman E. Sharpless and Dr. Eliseo Pérez-Stable

    Even with participation of historically underrepresented groups in biomedical research training increasing, members of these groups are still less likely to be hired and become independently funded faculty researchers. To strengthen inclusive excellence in biomedical research, the NIH FIRST program is working to recruit diverse cohorts and build a research culture in which faculty can thrive. For this edition of the NCI Bottom Line blog, NIH institute Directors’ Dr. Sharpless and Dr. Pérez-Stable discuss the impact of administering the FIRST Faculty Cohort and FIRST Coordination and Evaluation Center awards on behalf of NIH.

  • A close up of two peoples hands on a desk that is covered with financial charts. One of the hands is pointing towards one of the chart pages. An open laptop is in the foreground.
    • By Dr. Norman E. Sharpless

    In this edition of the NCI Bottom Line, NCI Director Dr. Ned Sharpless breaks down some commonly asked questions from investigators about using the modular budget option with R01 grant applications. Dr. Sharpless addresses these questions using an analysis conducted by the NCI's Center for Research Strategy about modular versus non-modular budgets.

  • funding, grants, projects
    • By NCI Director Dr. Norman E. Sharpless

    On the heels of Congress extending the Continuing Resolution for FY 2022, the NCI Director addresses what short-term funding means for NCI’s grantee community. As in years past, Dr. Sharpless highlights the Institute’s interim payline policies for both competing and noncompeting grants.

  • Bottom Line Blog - Annual Plan FY 2023
    • By Dr. L. Michelle Bennett

    With special authorities granted in the National Cancer Act of 1971, NCI has been submitting an annual budget proposal directly to the President and Congress for 50 years. In early September, NCI released the Annual Plan & Budget Proposal for Fiscal Year 2023. In this edition of the NCI Bottom Line blog, Dr. Michelle Bennett discusses priorities from the annual plan that are especially relevant to current and future NCI-funded researchers, including NCI’s commitment to investigator-initiated research and raising the R01 payline to fund more highly meritorious research.

  • Fellows in a lab using a pipette
    • By Dr. Oliver Bogler

    In this edition of the NCI Bottom Line, the Center for Cancer Training Director Dr. Oliver Bogler details numerous changes to the institute’s training programs and how NCI intends to stay abreast of the needs of future generations of cancer researchers. Specifically, Dr. Bogler discusses changes to the K08 career development program, inclusivity within the T32 grant program, and details of a new developmental program for early-stage surgeon-scientists.

  • Mixed age range team of scientists in research laboratory conducting science experiments.
    • By L. Michelle Bennett, Ph.D.

    NCI’s Center for Research Strategy analyzed 26 years of data to better understand the funding trends of the NCI R01-funded workforce, focusing on the age and career stage of investigators. This data, recently published by Dr. L. Michelle Bennett et al. in the Journal of Clinical Investigation, shows how NCI is actively developing policies based on this understanding and looking into methods that sustainably fund more principal investigators.

  • Congress approves an NCI budget increase of nearly $120 million.
    • By Dr. Norman E. Sharpless

    With a final fiscal year 2021 budget passed by Congress, NCI Director, Dr. Norman E. Sharpless, turns to the NCI Bottom Line blog to provide the grantee community with an update on how the NCI plans to use the budget increase to expand paylines. With this continued increase in funding from Congress, NCI remains on its current trajectory to achieve the goal of reaching the 15th percentile by FY 2025.

  • Black woman researcher in front of an image of the globe
    • By Dr. Dinah S. Singer

    As we near the April deadline to submit Expressions of Interest, Dr. Singer takes the opportunity to provide an update to the cancer research community on the Cancer Grand Challenges program and nine scientific challenges. Cancer Grand Challenges will fund novel ideas by multidisciplinary research teams from around the world that offer the potential to advance bold cancer research and improve outcomes for people affected by cancer. Additionally, Dr. Singer expands on the joint January 12th preapplication webinar which served to answer the research community’s questions about the program and application processes.

  • grants
    • By Dr. Norman E. Sharpless

    For this edition of the NCI Bottom Line blog, the NCI Director addresses what short-term funding from a continuing resolution means for NCI’s FY 2021 interim paylines. Specifically, Dr. Sharpless highlights the Institute’s interim policies for both competing and noncompeting grants.

  • NCI Grants and Paylines Graph
    • By L. Michelle Bennett, Ph.D.

    In this blog, Dr. Michelle Bennett, director of NCI’s Center for Research Strategy, provides an overview of the FY 2022 Annual Plan and Budget Proposal. This blog post highlights NCI’s proposal to increase paylines and showcases patient stories that inform our scientific strategy and planning.

  • NCI and Cancer Research UK collaboration
    • By Dr. Dinah S. Singer

    For this edition of the NCI Bottom Line, Dr. Singer highlights what NCI and CRUK’s new partnership, Cancer Grand Challenges, means for cancer research. Cancer Grand Challenges will fund novel ideas by multidisciplinary research teams from around the world that offer the potential to advance bold cancer research and improve outcomes for people affected by cancer.

  • SeroNet Researcher
    • By Dr. Douglas R. Lowy and Dr. Dinah S. Singer

    Following up to her most recent NCI Bottom Line post, Dr. Dinah Singer, along with Dr. Doug Lowy, provides readers an update on SeroNet, and expands on three additional components of the network. In addition to the Centers of Excellence and serological sciences projects, Drs. Lowy and Singer provide in-depth details about the SeroNet Serology Lab, Serological Sciences Capacity Building Centers, and a SeroNet Coordinating Center.

  • Female scientists with blood collection tube
    • By Dr. Dinah S. Singer

    In light of the COVID-19 pandemic, this edition of the NCI Bottom Line by Dr. Dinah Singer highlights and expands upon NCI’s recently launched Serological Sciences Network (SeroNet). Specifically, Dr. Singer describes the five components included in this initiative, as well as elaborates on the subsequent funding opportunities.

  • Word cloud based on key words in the RFA title
    • By Paulette Gray, Ph.D.

    In this edition of the NCI Bottom Line, the Director of the Division of Extramural Activities, Dr. Paulette Gray, discusses the concepts presented at the recent virtual Board of Scientific Advisors meeting. While this blog links to and recaps all 13 concepts presented, Dr. Gray highlights the Glioblastoma Therapeutics Network, CISNET Incubator Program for New Cancer Sites, and the Pediatric Preclinical Testing Public Private Partnership (PPTP3).

  • A close-up of glove-covered fingers holding a sample vial with the label “Coronavirus (2019-nCoV)” along with a bar code. The vial has a very dark liquid. In the background, out of focus, is a clear bottle with blue top.
    • By Dr. Dinah S. Singer

    In response to Dr. Singer’s presentation at the virtual 2020 annual meeting of the American Association for Cancer Research (AACR), this edition of the NCI Bottom Line highlights examples of how NCI continues to make progress in cancer research during the era of COVID-19. Dr. Singer also provides details on how NCI, working with NIH, has implemented new flexibilities for the cancer research community during this crisis.

  • Trainee taking part in online learning
    • By Dr. Oliver Bogler

    Following Dr. Sharpless’s most recent NCI Bottom Line post about NCI’s grant operations during the COVID-19 pandemic, the Center for Cancer Training’s (CCT) director, Dr. Oliver Bogler, addresses grantees about cancer research training during this unprecedented time. He also advises the cancer research community to continue to follow NIH/NCI grants guidance and suggests some ideas for how grantees and trainees can use their time.

  • Close-up of a microscope being operated by a person wearing blue gloves. The microscope's lens is focused on a glass slide with light illuminating the sample.
    • By NCI Director, Dr. Norman E. Sharpless

    In this edition of the NCI Bottom Line, NCI Director Dr. Norman E. Sharpless addresses the grantee community about NCI funding and operations during the COVID-19 public health emergency. Dr. Sharpless highlights NCI’s peer review schedule, our program staff, as well as general NCI grants administration processes during this time.

  • Photo of a magnifying glass over an orange percentage sign
    • By NCI Deputy Director, Dinah S. Singer, Ph.D.

    For this edition of the NCI Bottom Line, NCI Deputy Director, Dr. Dinah Singer elaborates on her February 11th presentation to the National Cancer Advisory Board. In this blog, Dr. Singer highlights a potential new policy from the NCI regarding a plan to implement minimum level of effort requirements for the following type of grants: U01, R01, R21, and P01.

  • Fiscal Year 2020 Budget Increase for NCI
    • By NCI Director, Dr. Norman E. Sharpless

    For this edition of the NCI Bottom Line, NCI Director, Dr. Norman E. Sharpless provides an update to the fiscal year (FY) 2020 budget and what exactly that means for NCI, research awards and paylines. Dr. Sharpless further discusses the grant policies that surround both competing and noncompeting grants from NCI.

  • NCI Competing Grants FY 2020 CR Interim Paylines. R01 Grants for Established & New Investigators - 8th Percentile; R01 Grants for Early Stage Investigators (ESIs) - 14th Percentile; R21 Grants - 7th Percentile
    • By Patrick McGarey

    For this edition of the NCI Bottom Line, Patrick McGarey, NCI’s Associate Director of Finance and Legislation provides an overview of NCI’s interim funding policy for Fiscal Year 2020. Furthermore, this blog post highlights the historical nature of functioning under a continuing resolution, and what a continuing resolution means for the NCI, as well as NCI’s grantee community.

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