NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 8,020 terms related to cancer and medicine.
- B-cell leukemia/lymphoma 2 protein
- listen (... sel loo-KEE-mee-uh/lim-FOH-muh 2 PROH-teen)
- A protein that helps control whether a cell lives or dies by blocking a type of cell death called apoptosis. The gene for the B-cell leukemia/lymphoma 2 protein is found on chromosome 18, and transfer of the B-cell leukemia/lymphoma 2 gene to a different chromosome is seen in many B-cell leukemias and lymphomas. This causes the B-cell leukemia/lymphoma 2 protein to be made in larger amounts, which may keep cancer cells from dying. Also called BCL2.