Bone Cancer Research
ETV6 Protein Could Be an Important Target for Ewing Sarcoma TreatmentPosted:
The protein ETV6 appears to promote tumor growth by affecting the behavior of the EWS-FLI1 fusion protein that drives most Ewing sarcomas. The research groups that made the discovery hope it leads to a targeted therapy for the aggressive childhood cancer.
Ifosfamide May Be Treatment of Choice for Some People with Ewing Sarcoma, Trial ShowsPosted:
New findings from the first large, randomized clinical trial to compare chemotherapy regimens for relapsed or treatment-resistant Ewing sarcoma could help doctors and patients select treatments.
NCI study provides genetic insights into osteosarcoma in childrenPosted:
A new study offers insight into genetic alterations associated with osteosarcoma, the most common bone tumor of children and adolescents, and the findings have implications for genetic testing of children with osteosarcoma and their families.
Study Identifies Potential Drug Combination for Ewing SarcomaPosted:
From experiments in cells and mice, researchers have identified a two-drug combination that kills more Ewing sarcoma cells than either drug on its own. The study findings could help inform future clinical trials.
In Mice, New Drug Conjugate Suggests Promise for Hard-to-Treat Pediatric CancersPosted:
Findings from a study in mice suggests that a new type of drug conjugate may have potential as a treatment for two cancers that are often diagnosed in children.