Risk Groups for Childhood Acute Lymphoblastic Leukemia
Key Points for This Section
In childhood ALL, risk groups are used to plan treatment.
Other factors that affect the risk group include the following:
- Whether the leukemia cells began from B lymphocytes or T lymphocytes.
- Whether there are certain changes in the chromosomes or genes of the lymphocytes.
- How quickly and how low the leukemia cell count drops after initial treatment.
- Whether leukemia cells are found in the cerebrospinal fluid at diagnosis.
It is important to know the risk group in order to plan treatment. Children with high-risk ALL usually receive more anticancer drugs and higher doses of anticancer drugs than children with standard-risk ALL.