Treatment Clinical Trials for Childhood Medulloblastoma
Clinical trials are research studies that involve people. The clinical trials on this list are for childhood medulloblastoma treatment. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Erdafitinib in Treating Patients with Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders with FGFR Mutations (A Pediatric MATCH Treatment Trial)
This phase II Pediatric MATCH trial studies how well erdafitinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that have spread to other places in the body and have come back or do not respond to treatment with FGFR mutations. Erdafitinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Location: 114 locations
Phase II Pediatric Study With Dabrafenib in Combination With Trametinib in Patients With HGG and LGG
The purpose of this study is to investigate the activity of dabrafenib in combination with trametinib in children and adolescent patients with BRAF V600 mutation positive low grade glioma or relapsed or refractory high grade glioma.
Location: 10 locations
Mebendazole in Treating Patients with Recurrent or Progressive Pediatric Brain Tumors
This phase I clinical trial studies the side effects and best dose of mebendazole in treating patients with pediatric brain tumors that have come back or have not responded to treatment. Mebendazole is used to treat parasitic infections and may slow the growth of tumor cells by interfering with cell structure and preventing new tumor blood vessels from forming.
Location: 2 locations