Screening Clinical Trials for Colorectal Cancer

Clinical trials are research studies that involve people. The clinical trials on this list are for colorectal cancer screening. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • Universal Screening for Lynch Syndrome in Patients with Newly Diagnosed Colorectal Cancer or Endometrial Cancer and Their Relatives

    This clinical trial studies universal screening for lynch syndrome in patients with newly diagnosed colorectal cancer or endometrial cancer and their relatives. Lynch syndrome is a hereditary cancer syndrome caused by a non-working gene that significantly increases the risk for an individual to develop colorectal cancer, endometrial cancer, and other cancers during one’s lifetime. A universal screening protocol for lynch syndrome may help reduce morbidity (cancer or its symptoms) and mortality (death) from cancer in the patients themselves and their at-risk relatives through early surveillance and prevention options.
    Location: 14 locations

  • Internet-Based Motivational Interviewing Intervention for Colonoscopy in African Americans

    The trial aims to develop and test an app, called e-Motivate, designed to improve African Americans’ screening colonoscopy rates. The app is a 20-minute app provided to individuals in the clinic after they receive a referral for a screening colonoscopy. Participants enrolled in the trial are randomly assigned to one of two conditions: app condition or control condition. Participants in the control condition receive usual care (e.g., patient navigation). Participants in the app condition complete the app and also receive usual care. Medical chart reviews (6 months post referral) will determine whether or not the participants completed the recommended screening colonoscopy. If proven efficacious, the app can be a useful tool to help increase African Americans’ screening colonoscopy rates and, in doing so, reduce the burden of colorectal cancer in the African American community.
    Location: Icahn School of Medicine at Mount Sinai, New York, New York