Screening Clinical Trials for Colorectal Cancer

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Clinical trials are research studies that involve people. The clinical trials on this list are for colorectal cancer screening. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-4 of 4
  • Universal Screening for Lynch Syndrome in Patients with Newly Diagnosed Colorectal Cancer or Endometrial Cancer and Their Relatives

    This clinical trial studies universal screening for lynch syndrome in patients with newly diagnosed colorectal cancer or endometrial cancer and their relatives. Lynch syndrome is a hereditary cancer syndrome caused by a non-working gene that significantly increases the risk for an individual to develop colorectal cancer, endometrial cancer, and other cancers during one’s lifetime. A universal screening protocol for lynch syndrome may help reduce morbidity (cancer or its symptoms) and mortality (death) from cancer in the patients themselves and their at-risk relatives through early surveillance and prevention options.
    Location: 14 locations

  • Educational Intervention in Improving Knowledge and Screening Rates of Colorectal Cancer

    This clinical trial studies how well educational intervention works in improving knowledge and screening rates of colorectal cancer. An educational intervention, such as viewing an inflatable colon, PowerPoint presentation, flip books, and flipcharts, may help improve knowledge about colorectal cancer and how often people get checked for colorectal cancers.
    Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio

  • Systems-Level Intervention in Increasing Colorectal Cancer Screening

    This randomized clinical trial studies a systems-level intervention in increasing colorectal cancer screening in community health centers. Researchers want to know whether using a community-based participatory research (CBPR) approach, comprised of community physicians, survivors, family advocates, researchers and representatives of community based organizations, can increase colorectal cancer by collaboratively selecting a menu of evidence-based systems-level screening intervention strategies. Based on the screening priorities identified, researchers want to test the effectiveness of these evidence-based system-level interventions in participants attending health care centers. A systems-level intervention may be effective in increasing colorectal cancer screening, which may help doctors find colorectal cancer sooner, when it may be easier to treat.
    Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri

  • Biomarkers for Early Detection of Colorectal Cancer in Adults Undergoing Colonoscopy

    This clinical trial studies biomarkers for early detection of colorectal cancer in participants undergoing colonoscopy. Studying samples of blood, stool, and urine from participants undergoing colonoscopy in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
    Location: 12 locations