Screening Clinical Trials for Liver Cancer

Clinical trials are research studies that involve people. The clinical trials on this list are for liver cancer screening. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • Abbreviated MRI versus Standard Ultrasound for Hepatocellular Carcinoma Screening and Surveillance in Patients with Cirrhosis

    This phase IV trial studies how well a new type of magnetic resonance imaging (MRI) exam called gadolinium contrast-enhanced abbreviated MRI (AMRI) works compared to a standard ultrasound exam to detect hepatocellular carcinoma (HCC) in patients with cirrhosis. Ultrasound is routinely used to monitor the livers of patients with cirrhosis who are at risk for HCC and to make decisions about their treatment. However, ultrasound has some limitations and is not the best choice for every patient. For these patients, computed tomography (CT) or MRI may be used. Gadolinium contrast is a liquid that is injected into the veins to make the organs more visible on MRI scans. This study will look at patients with cirrhosis to compare how well AMRI works compared to ultrasound to detect HCC.
    Location: 2 locations

  • Surveys, Blood Testing, and Fibroscan in Screening for Liver Fibrosis and Liver Cirrhosis

    This clinical trial studies the use of surveys, blood testing, and fibroscan in screening for liver fibrosis and liver cirrhosis in new or existing patients of the HOPE clinic seeking usual clinical care. Fibroscan is an imaging procedure of the liver which uses a probe like an ultrasound. Information gathered from this study may help researchers learn more about how to prevent or find liver cancer in patients who are currently receiving care at the HOPE clinic. Early detection of liver cancer may improve survival.
    Location: M D Anderson Cancer Center, Houston, Texas

  • MRI in Predicting Liver Toxicity in Patients with Liver or Intrahepatic Bile Duct Cancer Undergoing Radiation Therapy

    This pilot clinical trial studies magnetic resonance imaging (MRI) in predicting liver toxicity in patients with liver or intrahepatic bile duct cancer undergoing radiation therapy (RT). MRI is a procedure in which radio waves and a powerful magnet linked to a computer are used to create detailed pictures of areas inside the body. Imaging procedures, such as MRI, may help doctors predict which patients will develop liver toxicity and help plan the best treatment.
    Location: University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan