Prevention Clinical Trials for Rectal Cancer
Clinical trials are research studies that involve people. The clinical trials on this list are for rectal cancer prevention. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Eflornithine and / or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer
This phase III trial studies how well eflornithine works compared to sulindac in preventing the return of the disease (recurrence) of high-risk adenomas and second primary disease in patients with stage 0-III colon or rectal cancer. Drugs used in chemotherapy, such as eflornithine and sulindac, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Location: 779 locations
Mesh Reinforcement of Ileostomy Closure for the Prevention of Hernia Formation in Left Sided Colon or Rectal Cancer Patients, SCAR Study
This trial studies the feasibility of placing a mesh to reinforce the closure of the abdominal wall and prevent hernia formation in left sided colon or rectal cancer patients with an ileostomy. Hernias are a common occurrence and may put unnecessary burden on patients. Reinforcement of an ileostomy closure with mesh may help to prevent the occurrence of hernia formation.
Location: Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire
Epigallocatechin Gallate in Treating Patients with Colorectal Cancer That Can Be Removed by Surgery
This early phase I trial studies how well epigallocatechin gallate works in treating patients with colorectal cancer that can be removed by surgery. Epigallocatechin gallate is a dietary supplement that may help prevent colorectal cancer.
Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas