Prevention Clinical Trials for Rectal Cancer
Clinical trials are research studies that involve people. The clinical trials on this list are for rectal cancer prevention. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Eflornithine and / or Sulindac in Preventing Recurrence of High-Risk Adenomas and Second Primary Disease in Patients with Stage 0-III Colon or Rectal Cancer
This phase III trial studies how well eflornithine works compared to sulindac in preventing the return of the disease (recurrence) of high-risk adenomas and second primary disease in patients with stage 0-III colon or rectal cancer. Drugs used in chemotherapy, such as eflornithine and sulindac, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
Location: 775 locations
Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)
This study evaluates the investigational drug PledOx in the prevention of chronic chemotherapy induced peripheral neuropathy (CIPN) induced by the drug oxaliplatin.
Location: Mayo Clinic Health System-Franciscan Healthcare, La Crosse, Wisconsin
Epigallocatechin Gallate in Treating Patients with Colorectal Cancer That Can Be Removed by Surgery
This early phase I trial studies how well epigallocatechin gallate works in treating patients with colorectal cancer that can be removed by surgery. Epigallocatechin gallate is a dietary supplement that may help prevent colorectal cancer.
Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas