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Treatment Clinical Trials for Soft Tissue Sarcoma

Review the soft tissue sarcoma treatment clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 101-122 of 122

Pomalidomide and Nivolumab for the Treatment of Virus-Associated Malignancies with or without HIV
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Talimogene Laherparepvec with Radiation Therapy for the Treatment of Locally Advanced and Unresectable Soft Tissue Sarcomas
Status: Active
Location: University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
Spatially Fractionated GRID Radiation Therapy for the Treatment of Soft Tissue Sarcoma in Patients Undergoing Standard Radiation Therapy and Surgery
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Consolidative Radiation Therapy for the Treatment of Pediatric and Young Adult Patients with Metastatic or Progressive Soft Tissue or Bone Sarcoma, Target-RT Trial
Status: Active
Location: Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Status: Active
Location: Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia
A Study of sEphB4-HSA in Kaposi Sarcoma
Status: Active
Location: UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma
Status: Active
Location: See ClinicalTrials.gov
A Study Evaluating MM-310 in Patients With Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
PM14 Administered Intravenously to Patients with Advanced Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
A Study of PSB205 in Subjects With Advanced Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
A Study of BND-35 in Participants With Advanced Solid Tumors
Status: Active
Location: University of Colorado, Denver, Colorado
Paclitaxel or Liposomal Doxorubicin for HIV-positive Persons with Kaposi Sarcoma
Status: Approved
Location: Location information is not yet available.
Metformin in Combination with Standard of Care Systemic Therapy for the Treatment of Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Status: Approved
Location: 2 locations
Zanzalintinib and Pembrolizumab for the Treatment of Advanced or Metastatic Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma, and High Grade Pleomorphic or Undifferentiated Sarcoma
Status: Approved
Location: M D Anderson Cancer Center, Houston, Texas
Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors
Status: Temporarily Closed to Accrual
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients with Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk
Status: Temporarily Closed to Accrual
Location: M D Anderson Cancer Center, Houston, Texas
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Status: Temporarily Closed to Accrual
Location: Northwestern University, Chicago, Illinois
Atezolizumab in Combination with Cyclophosphamide, Sorafenib, and Bevacizumab for the Treatment of Recurrent or Refractory Solid Tumors in Pediatric Patients, ANGIO-A Study
Status: Temporarily Closed to Accrual
Location: Saint Jude Children's Research Hospital, Memphis, Tennessee
Gemcitabine and Docetaxel with Radiation Therapy before Surgery for the Treatment of High Grade and Greater than 5 cm Soft Tissue Sarcoma of the Extremities
Status: Temporarily Closed to Accrual
Location: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Bevacizumab and Temsirolimus Alone or in Combination with Valproic Acid or Cetuximab in Treating Patients with Advanced or Metastatic Malignancy or Other Benign Disease
Status: Temporarily Closed to Accrual
Location: M D Anderson Cancer Center, Houston, Texas
A Study of EGFR806 CAR T-Cell Immunotherapy for Treating Children and Young Adults with Recurrent/Refractory Solid Tumors
Status: Temporarily Closed to Accrual
Location: Fred Hutch/University of Washington/Seattle Children's Cancer Consortium, Seattle, Washington
DNX-2440 for Resectable Colorectal Liver Metastasis
Status: Temporarily Closed to Accrual
Location: See ClinicalTrials.gov