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Treatment Clinical Trials for Soft Tissue Sarcoma

Review the soft tissue sarcoma treatment clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 101-125 of 128

RNA-Lipid Particle Vaccine for the Treatment of Early Melanoma Recurrence after Anti-PD-1 Antibody Therapy or Uresectable or Metastatic Soft Tissue Sarcoma
Status: Active
Location: UF Health Cancer Institute - Gainesville, Gainesville, Florida
Palbociclib with Pembrolizumab for the Treatment of Patients with Locally Advanced, Metastatic or Unresectable Sarcomas
Status: Active
Location: University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
Tumor Infiltrating Lymphocytes for the Treatment of Children with High Risk Solid Tumors
Status: Active
Location: Johns Hopkins All Children's Hospital, Saint Petersburg, Florida
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Pomalidomide and Nivolumab for the Treatment of Virus-Associated Malignancies with or without HIV
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Talimogene Laherparepvec with Radiation Therapy for the Treatment of Locally Advanced and Unresectable Soft Tissue Sarcomas
Status: Active
Location: University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa
Spatially Fractionated GRID Radiation Therapy for the Treatment of Soft Tissue Sarcoma in Patients Undergoing Standard Radiation Therapy and Surgery
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Consolidative Radiation Therapy for the Treatment of Pediatric and Young Adult Patients with Metastatic or Progressive Soft Tissue or Bone Sarcoma, Target-RT Trial
Status: Active
Location: Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland
A Study of sEphB4-HSA in Kaposi Sarcoma
Status: Active
Location: UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas
KQB198 in Combination With Imatinib in Participants With Advanced/Metastatic GIST in 1st Line Setting
Status: Active
Location: 4 locations
Recombinant Glycosylated Human Interleukin-7 (CYT107) for the Treatment of Kaposi Sarcoma in Participants With HIV and Immune Non-Response (REGIMENKS HIV)
Status: Active
Location: See ClinicalTrials.gov
Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma
Status: Active
Location: See ClinicalTrials.gov
A Study Evaluating MM-310 in Patients With Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
PM14 Administered Intravenously to Patients with Advanced Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
A Study of PSB205 in Subjects With Advanced Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
A Study of BND-35 in Participants With Advanced Solid Tumors
Status: Active
Location: See ClinicalTrials.gov
Paclitaxel or Liposomal Doxorubicin for HIV-positive Persons with Kaposi Sarcoma
Status: Approved
Location: Location information is not yet available.
Metformin in Combination with Standard of Care Systemic Therapy for the Treatment of Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Status: Approved
Location: 2 locations
Proton-Spatially Fractionated Radiotherapy and Standard Radiation Therapy for the Treatment of Newly Diagnosed Retroperitoneal Soft Tissue Sarcoma
Status: Temporarily Closed to Accrual
Location: 2 locations
Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients with Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk
Status: Temporarily Closed to Accrual
Location: M D Anderson Cancer Center, Houston, Texas
Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid Tumors
Status: Temporarily Closed to Accrual
Location: National Institutes of Health Clinical Center, Bethesda, Maryland
Tazemetostat, Nivolumab, and Ipilimumab for the Treatment of SMARCB1- or SMARCA4-Deficient Tumors in Children, TAZNI Study
Status: Temporarily Closed to Accrual
Location: 4 locations
Atezolizumab in Combination with Cyclophosphamide, Sorafenib, and Bevacizumab for the Treatment of Recurrent or Refractory Solid Tumors in Pediatric Patients, ANGIO-A Study
Status: Temporarily Closed to Accrual
Location: 2 locations