Clinical Trials Using Anti-CD33/CD3 BiTE Antibody AMG 330

Clinical trials are research studies that involve people. The clinical trials on this list are studying Anti-CD33/CD3 BiTE Antibody AMG 330. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • A Phase 1 Study of AMG 330 in Subjects With Relapsed / Refractory Acute Myeloid Leukemia

    The purpose of this First-in-Human Phase 1 study is to determine if AMG 330 given as a continuous IV infusion is safe and tolerable in adult subjects that have relapsed / refractory Acute Myeloid Leukemia, and to determine the maximum tolerated dose and / or a biologically active dose. The study will be conducted in multiple sites and test increasing doses of AMG 330. The safety of subjects will be monitored by intensive assessment of vital signs, electrocardiograms, physical examinations, and laboratory tests.
    Location: 3 locations