Clinical Trials Using Carbon C 11 Alpha-methyltryptophan

Clinical trials are research studies that involve people. The clinical trials on this list are studying Carbon C 11 Alpha-methyltryptophan. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • C11-AMT PET Imaging in Predicting Tumor Response to Pembrolizumab in Patients with Metastatic Melanoma

    This phase II trial studies how well carbon C 11 alpha-methyltryptophan (C11-AMT) positron emission tomography (PET) imaging works in predicting tumor response to pembrolizumab in patients with melanoma that has spread to other parts of the body. C11-AMT PET imaging may be a less invasive way to predict tumor response to pembrolizumab.
    Location: 2 locations

  • AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants with Metastatic Well Differentiated Neuroendocrine Neoplasm

    This phase II trial studies how well telotristat etiprate works in treating participants with well differentiated neuroendocrine neoplasm that has spread to other places in the body and monitored by carbon C 11 alpha-methyltryptophan (AMT)-emission tomography (PET). Telotristat etiprate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Studying the changes within the tumor cells via AMT-PET may help doctors better understand how tumors respond to treatment with telotristat etiprate.
    Location: Wayne State University / Karmanos Cancer Institute, Detroit, Michigan

  • MRI and PET in Diagnosing Cognitive and Brain Changes in Older Patients with Invasive Breast Cancer Undergoing Chemotherapy

    This pilot clinical trial studies how well magnetic resonance imaging (MRI) and positron emission tomography (PET) work in diagnosing cognitive and brain changes in older patients with breast cancer that has spread into surrounding healthy tissue and who are undergoing chemotherapy. Analyzing thinking abilities and brain images before and after chemotherapy may help doctors identify people at risk for cognitive side effects of the treatment and better understand effects of treatment on brain structure and function.
    Location: 2 locations