Clinical Trials Using Copper Gluconate

Clinical trials are research studies that involve people. The clinical trials on this list are studying Copper Gluconate. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • Disulfiram and Copper Gluconate for the Treatment of Recurrent or Refractory Multiple Myeloma

    This phase I trial finds the best does of disulfiram and copper gluconate in treating patients with multiple myeloma that has come back (recurrent) or does not respond to treatment (refractory). Disulfiram is a drug used for alcohol aversion therapy. Copper gluconate is a dietary food supplement. This trial aims to see whether giving disulfiram and copper gluconate is safe in treating multiple myeloma.
    Location: Huntsman Cancer Institute / University of Utah, Salt Lake City, Utah

  • Copper Chloride, Disulfiram, and Copper Gluconate in Treating Patients with Metastatic Castration-Resistant Prostate Cancer

    This phase Ib trial studies the side effects and best dose of copper chloride when given together with disulfiram and copper gluconate in treating patients with castration-resistant prostate cancer that has spread to other places in the body. Copper chloride, disulfiram, and copper gluconate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
    Location: Duke University Medical Center, Durham, North Carolina

  • Disulfiram and Copper Gluconate with Radiation Therapy and Temozolomide in Treating Patients with Newly Diagnosed Glioblastoma That Can Be Removed by Surgery

    This phase I / II trial studies the side effects and best dose of disulfiram when given together with copper gluconate, radiation therapy, and temozolomide and to see how well they work in treating patients with newly diagnosed glioblastoma that can be removed by surgery. Disulfiram may reduce tumor growth by blocking the activity necessary for tumor growth. Copper gluconate is a dietary supplement that may help disulfiram work better by making the tumor cells more sensitive to the drug. Giving disulfiram and copper gluconate together with radiation therapy and temozolomide may work better in treating patients with glioblastoma.
    Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri