Clinical Trials Using Dacomitinib
Clinical trials are research studies that involve people. The clinical trials on this list are studying Dacomitinib. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Dacomitinib with or without Osimertinib in Treating Patients with Metastatic EGFR Mutant Lung Cancers with Disease Progression on Osimertinib
This early phase I trial studies how well dacomitinib with or without osimertinib works in treating patients EGFR mutant lung cancers that has spread to other places in the body (metastatic) and has progressed after treatment with osimertinib. Dacomitinib and osimertinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Location: 7 locations
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
This phase Ib trial determines if samples from a patient’s cancer can be tested to find combinations of drugs that provide clinical benefit for the kind of cancer the patient has. This study is also being done to understand why cancer drugs can stop working and how different cancers in different people respond to different types of therapy.
Location: OHSU Knight Cancer Institute, Portland, Oregon