Clinical Trials Using Dinaciclib

Clinical trials are research studies that involve people. The clinical trials on this list are studying Dinaciclib. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed / Refractory Acute Myeloid Leukemia

    An open-label, dose-escalation study to assess safety, pharmacokinetics and efficacy as well as determine the recommended Phase 2 doses of co-administered therapy of dinaciclib and venetoclax for patients with relapsed or refractory Acute Myeloid Leukemia (R / R AML).
    Location: 6 locations

  • Veliparib and Dinaciclib in Treating Patients with Advanced Solid Tumors

    This phase I trial studies the side effects and the best dose of veliparib and dinaciclib in treating patients with solid tumors that have spread to other places in the body and usually cannot be cured or controlled with treatment. Veliparib and dinaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
    Location: 2 locations

  • Dinaciclib and Pembrolizumab in Treating Participants with Metastatic or Locally Advanced Breast Cancer That is Unresectable

    This phase Ib trial studies the best dose and side effects of dinaciclib when given together with pembrolizumab in treating participants with breast cancer that has spread to other places in the body or to nearby tissues and lymph nodes and cannot be removed by surgery. Dinaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as pembrolizumab, may interfere with the ability of tumor cells to grow and spread. Giving dinaciclib and pembrolizumab may work better in treating participants with breast cancer.
    Location: UCSF Medical Center-Mount Zion, San Francisco, California