Clinical Trials Using Fluorine F 18 Tetrafluoroborate
Clinical trials are research studies that involve people. The clinical trials on this list are studying Fluorine F 18 Tetrafluoroborate. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
VSV-hIFNbeta-NIS with or without Ruxolitinib Phosphate in Treating Patients with Stage IV or Recurrent Endometrial Cancer
This phase I trial studies the side effects and best dose of vesicular stomatitis virus-human interferon beta-sodium iodide symporter (VSV-hIFNbeta-NIS) with or without ruxolitinib phosphate in treating patients with stage IV endometrial cancer or endometrial cancer that has come back. The study virus, VSV-hIFNbeta-NIS, has been changed so that it has restricted ability to spread to tumor cells and not to healthy cells. It also contains a gene for a protein, NIS, which helps the body concentrate iodine making it possible to track where the virus goes. VSV-hIFNbeta-NIS may be able to kill tumor cells without damaging normal cells. Ruxolitinib phosphate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving VSV-hIFNbeta-NIS with ruxolitinib phosphate may work better in treating patients with endometrial cancer compared to VSV-hIFNbeta-NIS alone.
Location: Mayo Clinic, Rochester, Minnesota
18F-TFB PET / CT in Imaging Patients with Refractory or Metastatic Thyroid Cancer
This pilot clinical trial studies how well fluorine F 18 tetrafluoroborate (18F-TFB) positron emission tomography (PET) / computed tomography (CT) works in imaging patients with thyroid cancer that does not respond to treatment or has spread to other parts of the body. 18F-TFB PET / CT may provide better imaging for staging thyroid cancer and evaluating how well therapy works.
Location: Memorial Sloan Kettering Cancer Center, New York, New York