Clinical Trials Using Lidocaine Hydrochloride

Clinical trials are research studies that involve people. The clinical trials on this list are studying Lidocaine Hydrochloride. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • A Non-opioid Pain Control Regimen for Pain Management in Patients Undergoing Head and Neck Cancer Surgery

    This phase III trial studies how well a non-opioid pain control regimen administered before and during surgery works for pain management in patients undergoing head and neck cancer surgery. Opioids are a class of drugs that work in the brain to produce a variety of effects, including pain relief. In addition to controlling pain, opioids can make some people feel "high" and can be addictive. Acetaminophen, celecoxib, gabapentin, ketamine and lidocaine are non-opioid medications that when given before and during surgery, may improve post-surgery pain and / or decrease opioid consumption, which may relieve opioid related side effects and adverse symptoms, improve quality of life, and decrease the risk of chronic pain.
    Location: Case Comprehensive Cancer Center, Cleveland, Ohio

  • Lidocaine Hydrochloride in Preventing Oxaliplatin-Induced Peripheral Neuropathy in Patients with Stage III-IV Colorectal Cancer

    This randomized phase I / II trial studies the best dose and side effects of lidocaine hydrochloride and how well it works in preventing oxaliplatin-induced peripheral neuropathy in patients with stage III-IV colorectal cancer. Lidocaine hydrochloride may work by blocking the nerve damaging effects of oxaliplatin.
    Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri