Clinical Trials Using Mogamulizumab
Clinical trials are research studies that involve people. The clinical trials on this list are studying Mogamulizumab. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Study of Mogamulizumab + Nivolumab in Subjects w / Locally Advanced or Metastatic Solid Tumors
The purpose of this study is to characterize the safety and tolerability and determine the maximum tolerated dose (MTD) or the recommended fixed dose of the combinations of mogamulizumab and nivolumab in subjects with locally advanced or metastatic solid tumors.
Location: 6 locations
KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors
The purpose of this study is to characterize the safety, tolerability, and determine the maximum tolerated dose (MTD) or the highest protocol-defined dose, in the absence of exceeding the MTD, of KHK2455 administered orally in combination with mogamulizumab to subjects with locally advanced or metastatic solid tumors.
Location: 3 locations
A Study of PF-05082566 In Combination With Mogamulizumab In Patients With Advanced Solid Tumors
This study is a Phase 1b, open label, multi center, multi-dose trial designed to estimate the maximum tolerated dose (MTD) and select the recommended dose for phase 2 (RP2D) investigations of PF- 05082566 in combination with KW-0761 (mogamulizumab) in patients with advanced solid tumors. Once the MTD of PF-05082566 administered in combination with KW-0761 is estimated (dose finding), one or more expansion cohorts of patients with selected advanced solid tumors (dose-expansion ) will be enrolled to further characterize the combination in term of safety profile, anti tumor activity, pharmacokinetics, pharmacodynamics and biomarkers modulation.
Location: 2 locations
Mogamulizumab in Treating Patients with Solid Tumors That Cannot Be Removed by Surgery
This phase I / II trial studies the safety and best dose of mogamulizumab and to see how well it works in treating patients with solid tumors that cannot be removed by surgery. Monoclonal antibodies, such as mogamulizumab, may block tumor growth in different ways by targeting certain cells that express C-C chemokine receptor 4 (CCR4).
Location: Memorial Sloan-Kettering Cancer Center, New York, New York