Clinical Trials Using Polyunsaturated Fatty Acid

Clinical trials are research studies that involve people. The clinical trials on this list are studying Polyunsaturated Fatty Acid. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-3 of 3
  • Omega-3 Supplementation in Prevention of Aromatase Inhibitor-Induced Toxicity in Patients with Stage I-III Breast Cancer

    This phase II trial studies the use of omega-3 fatty acid supplementation in preventing aromatase inhibitor-induced toxicity in patients with stage I-III breast cancer. An omega-3 supplementation may help relieve moderate to severe bone pain and improve joint symptoms caused by aromatase inhibitor-induced arthralgias.
    Location: 3 locations

  • Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

    This randomized phase II trial will evaluate if a low-fat diet with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
    Location: 2 locations

  • Effect of Omega-3 Fatty Acid and / or Letrozole on Hormone Levels in Obese Patients with Newly Diagnosed Estrogen Receptor Positive Breast Cancer before Surgery

    This randomized early phase I trial studies the effect of omega-3 fatty acid and / or letrozole on hormone levels in obese patients with newly diagnosed estrogen receptor positive breast cancer before surgery. Anti-inflammatory fish oils, called omega-3 fatty acids, are a type of fat obtained in the diet and involved in immunity and may block the effect of obesity on estrogen and tumor regrowth by blocking the production of estrogen to prevent the regrowth of breast cancer and reduce swelling and inflammation from substances produced in the body. Estrogen can cause the growth of breast cancer cells. Letrozole may help fight breast cancer by lowering the amount of estrogen made by the body. It is not yet known whether omega-3 fatty acid or letrozole alone, or the combination of both is better in reducing hormone levels in obese patients with estrogen receptor positive breast cancer.
    Location: Cancer Therapy and Research Center at The UT Health Science Center at San Antonio, San Antonio, Texas