Clinical Trials Using Vactosertib
Clinical trials are research studies that involve people. The clinical trials on this list are studying Vactosertib. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
Dose Escalation and Proof-of-Concept Studies of Vactosertib (TEW-7197) Monotherapy in Patients With MDS
This is a prospective, open-label, multicenter, phase 1 / 2 study of TEW-7197 in patients with low and intermediate risk of myelodysplastic syndrome (MDS).
Location: 2 locations
Vactosertib and Pomalidomide in Treating Participants with Relapsed or Relapsed and Refractory Multiple Myeloma
This phase I trial studies the side effects and best dose of vactosertib when given together with pomalidomide in treating participants with multiple myeloma that has come back after treatment or has come back and does not respond to treatment. Vactosertib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Pomalidomide may stop the growth of cancer cells by blocking the growth of new blood vessels necessary for tumor growth. Giving vactosertib and pomalidomide may work better in treating participants relapsed or relapsed and refractory multiple myeloma.
Location: Case Comprehensive Cancer Center, Cleveland, Ohio