Clinical Trials Using Water O-15

Clinical trials are research studies that involve people. The clinical trials on this list are studying Water O-15. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • 18F-Fluoromisonidazole-, Fludeoxyglucose F18-, and Water O-15-Labeled PET in Measuring Tumor Hypoxia in Patients with Newly Diagnosed Brain Tumors or Brain Metastases

    This clinical trial studies 18F-fluoromisonidazole (FMISO)-, fludeoxyglucose F18 (FDG)-, and water O-15-labeled positron emission tomography (PET) in measuring tumor hypoxia in patients with newly diagnosed brain tumors or brain metastases. Diagnostic procedures using FMISO, FDG, or water O-15 to find oxygen in tumor cells may help measure tumor hypoxia. It is not yet known whether FMISO PET is more effective than FDG-PET in measuring tumor hypoxia.
    Location: Huntsman Cancer Institute / University of Utah, Salt Lake City, Utah

  • Multi-tracer PET in Imaging Patients with Brain Tumors

    This pilot clinical trial studies multi-tracer positron emission tomography (PET) in imaging patients with brain tumors. PET uses radioactive labels (tracer), such as fludeoxyglucose F 18 (18F-FDG), fluorine F 18 fluorothymidine (18F-FLT), carbon 11 acetate (11C-ACE), or oxygen 15 water (15O-H2O), which can recognize differences between tumor and healthy brain. Multi-tracer PET may help find tumor proliferation (movement), glucose metabolism (sugars), blood flow, and growth rate in order to better predict treatment response.
    Location: Huntsman Cancer Institute / University of Utah, Salt Lake City, Utah