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2020 - RAS Dialogue Blog

    • The RASopathies Network
      , by Lisa Schoyer and Beth Stronach

      RASopathies are neurodevelopmental genetic syndromes caused by germline mutations in RAS pathway genes that result in increased MAPK signaling. The RASopathies Network provides an umbrella organization to connect affected families with researchers.

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    • Intravenous High-Dose Vitamin C in Cancer Therapy
      , by Lewis Cantley and Jihye Yun

      Pharmacologic levels of vitamin C in plasma can only be achieved by intravenous administration. Vitamin C undermines RAS-mutant cells’ reliance on upregulation of glycolysis and antioxidant activities to support their cancer lifestyle.

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