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Prevention Clinical Trials for Breast Cancer

Review the breast cancer prevention clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 1-25 of 34

Finding the Best Tamoxifen Dose for Breast Cancer Risk Reduction in Premenopausal Women, RENAISSANCE Trial
Status: Active
Location: 11 locations
A Study of Blood Pressure Control During Breast Cancer Treatment for Prevention of Cardiotoxicity
Status: Active
Location: 7 locations
A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People with Breast Cancer
Status: Active
Location: 7 locations
Bazedoxifene and Conjugated Estrogens for the Prevention of Breast Cancer in Peri- or Post-Menopausal Women at Increased Risk for Development of Breast Cancer
Status: Active
Location: 6 locations
SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery
Status: Active
Location: 5 locations
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Status: Active
Location: 4 locations
Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer
Status: Active
Location: 3 locations
STEMVAC in Patients with Early Stage Triple Negative Breast Cancer
Status: Active
Location: 3 locations
Metformin and Nightly Fasting in Women with Early Breast Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Acolbifene versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer
Status: Active
Location: 3 locations
Exercise Intervention for the Prevention of Obesity and Improvement of Movement in Stage 0-III Breast Cancer Survivors
Status: Active
Location: 2 locations
Remotely Delivered, Culturally Tailored Weight Loss Interventions Among Latina Breast Cancer Survivors, ¡Vida! Trial
Status: Active
Location: Fred Hutch/University of Washington/Seattle Children's Cancer Consortium, Seattle, Washington
Chinese Herbal Complementary and Alternative Medicine for the Prevention of Side Effects from Radiation Therapy
Status: Active
Location: University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Immediate Lymphatic Reconstruction for the Prevention of Lymphedema in Patients with Breast Cancer, LILY Trial
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Carvedilol and/or Empagliflozin for the Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-Directed Therapy, HER2HEART-US Trial
Status: Active
Location: Siteman Cancer Center at Washington University, Saint Louis, Missouri
Low Dose Tamoxifen with or without Omega-3 Fatty Acids for Breast Cancer Risk Reduction
Status: Active
Location: University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Vaccine Therapy (INO-5401 with or without INO-9012) Followed by Electroporation in Adult Cancer and Non-cancer Patients with BRCA1 or BRCA2 Mutations
Status: Active
Location: University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Surgical Irrigation Solution (Xperience, Trademark) for the Prevention of Surgical Site Infection in Post-Mastectomy Reconstruction
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Together After Cancer
Status: Active
Location: University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida
Fruit and Vegetable Intervention in Lactating Women to Reduce Breast Cancer Risk
Status: Active
Location: University of Massachusetts, Amherst, Amherst, Massachusetts
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women, LIN-BRiCK Trial
Status: Active
Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
A Resistance and Aerobic Training Exercise Intervention for the Prevention of Breast Cancer in Women with Dense Breasts, REP-D Trial
Status: Active
Location: 2 locations
Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer
Status: Active
Location: City of Hope Comprehensive Cancer Center, Duarte, California
Indocyanine Green-Guided Manual Lymphatic Drainage for the Prevention of Late-Stage Breast Cancer Related Lymphedema in Breast Cancer Patients Undergoing Axillary Node Dissection
Status: Active
Location: University of Florida Health Science Center - Gainesville, Gainesville, Florida
A Fiber-Diverse, Anti-Inflammatory Diet and Aerobic Exercise for Reducing Risk of Breast Cancer Recurrence in Survivors
Status: Active
Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California