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Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Prevention Clinical Trials for Colorectal Cancer

Review the colorectal cancer prevention clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 1-20 of 20

A Study to Examine How Often (Every 5 Years or 10 Years) a Colonoscopy Should be Done in Participants Who Had One or Two Small Growths of Tissue Removed from Their Colon
Status: Active
Location: 430 locations
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
Status: Active
Location: 5 locations
Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Dietary Supplement (HVMN Ketone-IQ) for the Prevention of the Development and Progression of Intestinal Adenomas in Patients with Familial Adenomatous Polyposis, BHB-FAP Trial
Status: Active
Location: University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
Cryotherapy for the Prevention of Chemotherapy-Induced Peripheral Neuropathy in Patients with Stage III Colon Cancer Receiving Oxaliplatin
Status: Active
Location: Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York
Coffee Intake and Changes in the Gut Microbiome in Patients with Stage I-III Colorectal Cancer, COMMENCER Trial
Status: Active
Location: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
A Standardized Diet before Colorectal Cancer Surgery for the Prevention of Colorectal Cancer Recurrence and Metastasis after Surgery in Patients with Colorectal Cancer, The DIET Trial
Status: Active
Location: University of Chicago Comprehensive Cancer Center, Chicago, Illinois
Bean Smoothie Supplementation Intervention for Improving Bowel Health in Healthy Adults
Status: Active
Location: University of California Davis Comprehensive Cancer Center, Sacramento, California
Atorvastatin with or without Aspirin in Preventing Colorectal Cancer in Patients with Lynch Syndrome
Status: Active
Location: Fox Chase Cancer Center, Philadelphia, Pennsylvania
A Community Health Worker Led (SBIRT) and Culturally Adapted (CAP) Program to Increase Colorectal Cancer Screening Among People at Higher Risk, CHURCH Trial
Status: Active
Location: NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York
Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
Status: Active
Location: University of Illinois, Chicago, Illinois
Mediterranean Diet and Weight Loss: Targeting the Bile Acid/Gut Microbiome Axis to Reduce Colorectal Cancer
Status: Active
Location: University of Illinois, Chicago, Illinois
Effect of Diet Interventions on the Gut Microbiota
Status: Active
Location: Moffitt Cancer Center, Tampa, Florida
A Nutrition and Exercise Prehabilitation Intervention to Reduce Inflammation in American Indian Patients with Obesity-Related Solid Tumor Cancer
Status: Active
Location: Banner University Medical Center - Tucson, Tucson, Arizona
A Sugary Drink Reduction Program to Reduce Colorectal Cancer
Status: Active
Location: University of Virginia Cancer Center, Charlottesville, Virginia
Walnuts and Colon Health
Status: Active
Location: University of Connecticut, Farmington, Connecticut
MyBestGI App for the Reduction of Colorectal Cancer Risk
Status: Active
Location: University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan
Designing a Dyad-Based mHealth Intervention to Improve Adherence to Lifestyle Recommendations in Colorectal Cancer Survivors and Their Family Caregivers
Status: Active
Location: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Testing Obeticholic Acid for Familial Adenomatous Polyposis
Status: Temporarily Closed to Accrual
Location: 6 locations
An Observational Research Study to Uncover Subtypes of Cancer Cachexia, LOTUS-CC Study
Status: Active
Location: 207 locations