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Esophageal Cancer Clinical Trials

Review the esophageal cancer clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 101-125 of 133

Genetic Testing on Blood Samples for Treatment Suggestions in Patients with Advanced or Metastatic Cancer
Status: Active
Location: 3 locations
Repeated Magnetic Resonance Imaging Scans for the Analysis of Cancer Response during Radiation Therapy, the RELAY Trial
Status: Active
Location: 2 locations
Indocyanine Green for Imaging of Solid Tumors during Surgery Compared to Standard of Care
Status: Active
Location: University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania
An Investigational Scan (18F-FAraG PET/CT) for Tumor Detection and Prediction of Treatment Response in Patients with Locally Advanced Esophageal Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
New PET Scan (68Ga-FAPI-46) for People with Cancers
Status: Active
Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients with Lung or Esophageal Cancer, EUCLID Trial
Status: Active
Location: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
Status: Active
Location: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in Gastrointestinal Cancer, PERICLES Study
Status: Temporarily Closed to Accrual
Location: 2 locations
Evaluation of a Population-Based Care Delivery Model to Match Evolving Patient Needs to Palliative Care Services for Community-Based Patients with Advanced Heart Failure or Cancer, TIER-PC Trial
Status: Active
Location: 5 locations
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients with Cancer
Status: Active
Location: Virginia K Crosson Cancer Center, Fullerton, California
Efficacy and Safety Study of OMTX705, Monotherapy and Anti-PD-1-combined, in Subjects With Advanced Solid Tumors.
Status: Active
Location: See ClinicalTrials.gov
A Pilot Study to Assess the Functional Capacity of Esophageal and Lung Cancer Patients Receiving Neoadjuvant Therapy
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Collecting Blood Samples from Patients with and without Cancer to Evaluate Tests for Early Cancer Detection
Status: Active
Location: 723 locations
Assessment of Esophageal Distensibility and Mucosal Impedance in Dysplastic Barrett's Esophagus Patients Undergoing Radiofrequency Ablation
Status: Active
Location: Mayo Clinic in Rochester, Rochester, Minnesota
Evaluating Outcomes in Patients with Barrett's Esophagus Undergoing Treatment with Resection and Endoscopic Ablation Techniques, Treat-Be Study
Status: Active
Location: 5 locations
Genetic and Epigenetic Analysis of Gastrointestinal Specimens
Status: Active
Location: City of Hope Comprehensive Cancer Center, Duarte, California
UNC Barrett's Esophagus and Esophageal Cancer Biorepository (BEECAB)
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-04)
Status: Active
Location: 3 locations
National Cancer Institute “Cancer Moonshot Biobank”
Status: Active
Location: 147 locations
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Status: Active
Location: 8 locations
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Status: Active
Location: 7 locations
Non-Endoscopic Detection of Barrett's Esophagus Using Methylation Biomarkers on EndoSign® Cell Collection Device Samples
Status: Active
Location: 3 locations
Impact of Radiation Modality on Immune Responses in Patients with Esophageal Cancer and Unresectable or Locally Recurrent Hepatocellular Carcinoma Receiving a Pneumococcal Vaccine
Status: Active
Location: 2 locations
18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Esophageal Cancer Risk Registry
Status: Active
Location: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania