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Government Funding Lapse
Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Esophageal Cancer Clinical Trials

Review the esophageal cancer clinical trials on this list and use the filters to refine the results by age and location. Some clinical trials are held at NCI-Designated Cancer Centers and may be supported by other organizations.

You can find more information about the types and phases of clinical trials and what to expect or use our Steps to Find a Clinical Trial.

Trials 101-125 of 130

An Investigational Scan (18F-FAraG PET/CT) for Tumor Detection and Prediction of Treatment Response in Patients with Locally Advanced Esophageal Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
New PET Scan (68Ga-FAPI-46) for People with Cancers
Status: Active
Location: UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California
PET/CT Imaging to Evaluate Cardiac Radiation Damage in Patients with Lung or Esophageal Cancer, EUCLID Trial
Status: Active
Location: Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
Ultrasound for the Diagnosis of Oxaliplatin-Induced Peripheral Neuropathy in Patients with Gastrointestinal Cancer
Status: Active
Location: Wake Forest University Health Sciences, Winston-Salem, North Carolina
Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers
Status: Active
Location: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Peritoneal Carcinomatosis Leveraging ctDNA Guided Treatment in Gastrointestinal Cancer, PERICLES Study
Status: Temporarily Closed to Accrual
Location: 2 locations
Evaluation of a Population-Based Care Delivery Model to Match Evolving Patient Needs to Palliative Care Services for Community-Based Patients with Advanced Heart Failure or Cancer, TIER-PC Trial
Status: Active
Location: 5 locations
Patient Navigation Program in Supporting Underrepresented Minorities with Advanced Gastrointestinal, Hematologic, or Thoracic Cancer in Genomic-Based Cancer Trial Enrollment, The SURGE Trial
Status: Active
Location: 3 locations
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients with Cancer
Status: Active
Location: Virginia K Crosson Cancer Center, Fullerton, California
Efficacy and Safety Study of OMTX705, Monotherapy and Pembrolizumab-combined, in Subjects With Advanced Solid Tumors.
Status: Active
Location: Beth Israel Deaconess Medical Center, Boston, Massachusetts
A Pilot Study to Assess the Functional Capacity of Esophageal and Lung Cancer Patients Receiving Neoadjuvant Therapy
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Collecting Blood Samples from Patients with and without Cancer to Evaluate Tests for Early Cancer Detection
Status: Active
Location: 719 locations
Assessment of Esophageal Distensibility and Mucosal Impedance in Dysplastic Barrett's Esophagus Patients Undergoing Radiofrequency Ablation
Status: Active
Location: Mayo Clinic in Rochester, Rochester, Minnesota
Evaluating Outcomes in Patients with Barrett's Esophagus Undergoing Treatment with Resection and Endoscopic Ablation Techniques, Treat-Be Study
Status: Active
Location: 5 locations
Genetic and Epigenetic Analysis of Gastrointestinal Specimens
Status: Active
Location: City of Hope Comprehensive Cancer Center, Duarte, California
UNC Barrett's Esophagus and Esophageal Cancer Biorepository (BEECAB)
Status: Active
Location: UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina
National Cancer Institute “Cancer Moonshot Biobank”
Status: Active
Location: 147 locations
ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
Status: Active
Location: 8 locations
cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
Status: Active
Location: 5 locations
Non-Endoscopic Detection of Barrett's Esophagus Using Methylation Biomarkers on EndoSign® Cell Collection Device Samples
Status: Active
Location: 2 locations
Impact of Radiation Modality on Immune Responses in Patients with Esophageal Cancer and Unresectable or Locally Recurrent Hepatocellular Carcinoma Receiving a Pneumococcal Vaccine
Status: Active
Location: 2 locations
18F-FSPG PET/CT as a Non-Invasive Imaging Biomarker for Treatment Response to Chemoradiation in Esophageal Cancer
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Esophageal Cancer Risk Registry
Status: Active
Location: University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania
Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated with Proton Therapy
Status: Active
Location: M D Anderson Cancer Center, Houston, Texas
Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining
Status: Active
Location: National Institutes of Health Clinical Center, Bethesda, Maryland