Localized Ewing Family of Tumors
Metastatic Ewing Family of Tumors
Recurrent Ewing Family of Tumors

A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

Treatment of localized Ewing family of tumors may include the following:

• Combination chemotherapy followed by surgery and/or radiation therapy.
• A clinical trial testing different drugs, doses, and treatment schedules.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with localized Ewing sarcoma/peripheral primitive neuroectodermal tumor.

Treatment of metastatic Ewing family of tumors may include the following:

• Combination chemotherapy followed by radiation therapy to the area where the tumor first formed and the places where the tumor has spread.
• A clinical trial of chemotherapy with either stem cell transplant or radiation therapy, for tumors that have spread to the lungs.
• A clinical trial of combination chemotherapy plus an angiogenesis inhibitor (a drug that blocks the growth of new blood vessels to the tumor).

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with metastatic Ewing sarcoma/peripheral primitive neuroectodermal tumor.

Treatment of recurrent Ewing family of tumors may include the following:

• Surgery followed by combination chemotherapy.
• Combination chemotherapy.
• High-dose chemotherapy and stem cell transplant using the patient's stem cells.
• Radiation therapy or surgery to remove bone tumors, as palliative therapy to reduce symptoms and improve the quality of life.
• Radiation therapy followed by surgery to remove tumors that have spread to the lungs.
• A clinical trial of a new treatment.

Check for U.S. clinical trials from NCI's PDQ Cancer Clinical Trials Registry that are now accepting patients with recurrent Ewing sarcoma/peripheral primitive neuroectodermal tumor.

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